Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3CA | P42336 | 1/20 | 0.40 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.40 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.39 |
| ▸ | NPC1 | O15118 | 3/20 | 0.39 |
| ▸ | RAB9A | P51151 | 3/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | IDO1 | P14902 | 2/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.37 |
| ▸ | TSHR | P16473 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | MAPK9 | P45984 | 1/20 | 0.36 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.36 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.33 |
| ▸ | KDR | P35968 | 5/20 | 0.32 |
| ▸ | FLT1 | P17948 | 1/20 | 0.32 |
| ▸ | FLT4 | P35916 | 1/20 | 0.32 |
| ▸ | ALOX15B | O15296 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21131348 | 0.88 | KDR (0.40) | KDM4ENPC1RAB9AALOX15TSHR | |
| SCHEMBL2040213 | 0.87 | ALDH1A1 (0.49) | ALOX15TSHRALDH1A1MAPK9MAPK10 | |
| SCHEMBL12076772 | 0.86 | ALDH1A1 (0.36) | KDM4ENPC1RAB9AMAPK1ALOX15 | |
| SCHEMBL22059891 | 0.86 | ALOX15 (0.37) | ALOX15TSHRALDH1A1MAPK9MAPK10 | |
| SCHEMBL21125555 | 0.85 | ALDH1A1 (0.36) | PIK3CAPIK3CBPIK3CGNPC1RAB9A | |
| SCHEMBL16566959 | 0.85 | KDR (0.38) | PIK3CAPIK3CBPIK3CGKDM4ENPC1 | |
| SCHEMBL21647270 | 0.85 | ALDH1A1 (0.48) | ALOX15TSHRALDH1A1MAPK9MAPK10 | |
| SCHEMBL30024343 | 0.85 | ALDH1A1 (0.48) | ALOX15TSHRALDH1A1MAPK9MAPK10 | |
| SCHEMBL29373868 | 0.85 | ALDH1A1 (0.48) | ALOX15TSHRALDH1A1MAPK9MAPK10 | |
| SCHEMBL30125198 | 0.85 | ALDH1A1 (0.48) | ALOX15TSHRALDH1A1MAPK9MAPK10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11136343-B2 | Binuclear metal complexes for use as emitters in organic electroluminescent devices | MERCK PATENT GMBH (DE) | 2021-10-05 | — | — | US | disclosed |
| US-11024815-B2 | Metal complexes | MERCK PATENT GMBH (DE) | 2021-06-01 | — | — | US | disclosed |
| EP-3507294-B1 | BINUCLEAR AND TRINUCLEAR METAL COMPLEXES COMPOSED OF TWO INTER-LINKED TRIPODAL HEXADENTATE LIGANDS FOR USE IN ELECTROLUMINESCENT DEVICES | MERCK PATENT GMBH (DE) | 2021-02-24 | — | — | EP | disclosed |
| US-10889604-B2 | Binuclear and trinuclear metal complexes composed of two inter-linked tripodal hexadentate ligands for use in electroluminescent devices | MERCK PATENT GMBH | 2021-01-12 | — | — | US | disclosed |
| EP-3515925-B1 | BINUCLEAR METAL COMPLEXES FOR USE AS EMITTERS IN ORGANIC ELECTROLUMINESCENT DEVICES | MERCK PATENT GMBH (DE) | 2020-10-21 | — | — | EP | disclosed |
| EP-3526227-B1 | BINUCLEAR METAL COMPLEXES AND ELECTRONIC DEVICES, IN PARTICULAR ORGANIC ELECTROLUMINESCENT DEVICES CONTAINING SAID METAL COMPLEXES | MERCK PATENT GMBH (DE) | 2020-06-03 | — | — | EP | disclosed |
| US-20200052213-A1 | BINUCLEAR METAL COMPLEXES AND ELECTRONIC DEVICES, IN PARTICULAR ORGANIC ELECTROLUMINESCENT DEVICES CONTAINING SAID METAL COMPLEXES | MERCK PATENT GMBH (DE) | 2020-02-13 | — | — | US | disclosed |
| US-20190292210-A1 | BINUCLEAR METAL COMPLEXES FOR USE AS EMITTERS IN ORGANIC ELECTROLUMINESCENT DEVICES | MERCK PATENT GMBH (DE) | 2019-09-26 | — | — | US | disclosed |
| EP-3254317-B1 | METAL COMPLEXES | MERCK PATENT GMBH (DE) | 2019-07-31 | — | — | EP | disclosed |
| US-20190202851-A1 | BINUCLEAR AND TRINUCLEAR METAL COMPLEXES COMPOSED OF TWO INTER-LINKED TRIPODAL HEXADENTATE LIGANDS FOR USE IN ELECTROLUMINESCENT DEVICES | MERCK PATENT GMBH (DE) | 2019-07-04 | — | — | US | disclosed |
| US-20180026209-A1 | Metal Complexes | MERCK PATENT GMBH (DE) | 2018-01-25 | — | — | US | disclosed |
| US-20180026209-A1 | Metal Complexes | MERCK PATENT GMBH (DE) | 2018-01-25 | — | — | US | disclosed |
| CN-106995466-A | Organometallic complex, light-emitting component, light-emitting device, electronic equipment and lighting device | 株式会社半导体能源研究所 | 2017-08-01 | — | — | CN | disclosed |
| US-20170213989-A1 | ORGANOMETALLIC COMPLEX, LIGHT-EMITTING ELEMENT, LIGHT-EMITTING DEVICE, ELECTRONIC DEVICE, AND LIGHTING DEVICE | SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) | 2017-07-27 | — | — | US | disclosed |
| US-20170213989-A1 | ORGANOMETALLIC COMPLEX, LIGHT-EMITTING ELEMENT, LIGHT-EMITTING DEVICE, ELECTRONIC DEVICE, AND LIGHTING DEVICE | SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) | 2017-07-27 | — | — | US | disclosed |
| US-20170213989-A1 | ORGANOMETALLIC COMPLEX, LIGHT-EMITTING ELEMENT, LIGHT-EMITTING DEVICE, ELECTRONIC DEVICE, AND LIGHTING DEVICE | SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) | 2017-07-27 | — | — | US | disclosed |
| WO-2016124304-A1 | METAL COMPLEXES | MERCK PATENT GMBH (DE) | 2016-08-11 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (8 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20190202851-A1 | BINUCLEAR AND TRINUCLEAR METAL COMPLEXES COMPOSED OF TWO INTER-LINKED TRIPODAL HEXADENTATE LIGANDS FOR USE IN ELECTROLUMINESCENT DEVICES | PARN, PUF60, PARG | PIK3CA 3118/4885PIK3CB 2359/4885PIK3CG 2294/4885 |
| US-20190292210-A1 | BINUCLEAR METAL COMPLEXES FOR USE AS EMITTERS IN ORGANIC ELECTROLUMINESCENT DEVICES | AP2M1, MCU, AP3M1 | PIK3CA 4539/4885PIK3CB 3341/4885PIK3CG 3164/4885 |
| US-11024815-B2 | Metal complexes | EXOC4, EXOC3, TIMCC | PIK3CA 3766/4885PIK3CB 2546/4885PIK3CG 2254/4885 |
| US-10889604-B2 | Binuclear and trinuclear metal complexes composed of two inter-linked tripodal hexadentate ligands for use in electroluminescent devices | PARN, PUF60, PARG | PIK3CA 3118/4885PIK3CB 2359/4885PIK3CG 2294/4885 |
| US-20170213989-A1 | ORGANOMETALLIC COMPLEX, LIGHT-EMITTING ELEMENT, LIGHT-EMITTING DEVICE, ELECTRONIC DEVICE, AND LIGHTING DEVICE | INTS9, CRY1, IK | PIK3CA 1803/4885PIK3CB 2131/4885PIK3CG 1600/4885 |
| US-20180026209-A1 | Metal Complexes | AP3M1, AP2M1, SOD1 | PIK3CA 4065/4885PIK3CB 3320/4885PIK3CG 2627/4885 |
| US-11136343-B2 | Binuclear metal complexes for use as emitters in organic electroluminescent devices | AP2M1, MCU, AP3M1 | PIK3CA 4539/4885PIK3CB 3341/4885PIK3CG 3164/4885 |
| US-20200052213-A1 | BINUCLEAR METAL COMPLEXES AND ELECTRONIC DEVICES, IN PARTICULAR ORGANIC ELECTROLUMINESCENT DEVICES CONTAINING SAID METAL COMPLEXES | BICRA, NCLN, IMMT | PIK3CA 3755/4885PIK3CB 2704/4885PIK3CG 2393/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.