Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.46 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.46 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | S100A4 | P26447 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | AHR | P35869 | 3/20 | 0.33 |
| ▸ | CYP2A6 | P11509 | 3/20 | 0.33 |
| ▸ | HPGD | P15428 | 2/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | ATM | Q13315 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11508298 | 0.82 | HSP90AA1 (0.37) | HSP90AA1TLR9ALOX15MAPK1ALDH1A1 | |
| SCHEMBL1798477 | 0.80 | HSP90AA1 (0.46) | HSP90AA1TLR9ALOX15MAPK1ALDH1A1 | |
| SCHEMBL7740400 | 0.78 | — | — | |
| SCHEMBL16401544 | 0.76 | CYP2A6 (0.36) | HSP90AA1TLR9ALOX15S100A4AHR | |
| SCHEMBL2366749 | 0.76 | DGAT1 (0.44) | HSP90AA1TLR9ALDH1A1S100A4LMNA | |
| SCHEMBL9725139 | 0.76 | PKM (0.38) | ALDH1A1AHRCYP2A6MAPTKMT2A | |
| SCHEMBL9328431 | 0.76 | KDM4E (0.41) | HSP90AA1TLR9ALOX15MAPK1ALDH1A1 | |
| SCHEMBL5158400 | 0.76 | SIGMAR1 (0.36) | HSP90AA1TLR9ALOX15MAPK1ALDH1A1 | |
| SCHEMBL11110756 | 0.76 | RAB9A (0.38) | HSP90AA1MAPK1ALDH1A1TDP1L3MBTL1 | |
| SCHEMBL2701308 | 0.76 | VCAM1 (0.36) | ALOX15ALDH1A1TDP1S100A4TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 48 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6380197-B1 | FOR TREATING AND PREVENTING A PLETHORA OF DISEASES INCLUDING DIABETES | AVENTIS PHARMA S. A. (FR) | 2002-04-30 | — | — | US | claimed |
| EP-1001943-A1 | POLYHYDROXYALKYLPYRAZINE DERIVATIVES, PREPARATION AND MEDICINES CONTAINING THEM | Aventis Pharma S.A. (FR) | 2000-05-24 | — | — | EP | claimed |
| WO-1999003843-A1 | POLYHYDROXYALKYLPYRAZINE DERIVATIVES, PREPARATION AND MEDICINES CONTAINING THEM | RHONE-POULENC RORER S.A. (FR) | 1999-01-28 | — | — | WO | claimed |
| US-5272215-A | Modified plastic elastomer block copolymers | THE WEST COMPANY, INCORPORATED (US) | 1993-12-21 | — | — | US | claimed |
| EP-4119605-A1 | BIO-BASED EVA COMPOSITIONS AND ARTICLES AND METHODS THEREOF | Braskem S.A. (BR) | 2023-01-18 | — | — | EP | disclosed |
| EP-2796455-A1 | METHOD FOR PRODUCING SULFONATE | Sumitomo Chemical Co., Ltd (JP) | 2014-10-29 | — | — | EP | disclosed |
| EP-1889826-B1 | METHOD FOR PRODUCING A HEXAHYDROFUROFURANOL DERIVATIVE | SUMITOMO CHEMICAL CO (JP) | 2011-10-26 | — | — | EP | disclosed |
| US-7951977-B2 | Process for producing hexahydrofurofuranol derivative | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2011-05-31 | — | — | US | disclosed |
| US-20090176999-A1 | Process for producing hexahydrofurofuranol derivative | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2009-07-09 | — | — | US | disclosed |
| EP-1889826-A1 | METHOD FOR PRODUCING HEXAHYDROFUROFURANOL DERIVATIVE | Sumitomo Chemical Company, Limited (JP) | 2008-02-20 | — | — | EP | disclosed |
| CN-100357388-C | Organic electroluminescent compositions | 3M INNOVATIVE PROPERTIES CO (US) | 2007-12-26 | — | — | CN | disclosed |
| CN-1681903-A | organic electroluminescent composition | 3M INNOVATIVE PROPERTIES CO (US) | 2005-10-12 | — | — | CN | disclosed |
| US-4886809-A | CARDIOTONIC AGENTS | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1989-12-12 | — | — | US | disclosed |
| US-4798890-A | SULFONATION OF A DITHIOAZETIDINONE | OTSUKA KAGAKU KABUSHIKI KAISHA (JP) | 1989-01-17 | — | — | US | disclosed |
| EP-0281242-A1 | Beta-alkylmelatonins | ELI LILLY AND COMPANY (US) | 1988-09-07 | — | — | EP | disclosed |
| US-4740596-A | Process for preparation of 4-sulfonylthio azetidinone derivatives | OTSUKA KAGAKU KABUSHIKI KAISHA (JP) | 1988-04-26 | — | — | US | disclosed |
| EP-0255134-A2 | Carbostyril derivatives and salts thereof, process for preparing them, and cardiotonic composition containing same | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1988-02-03 | — | — | EP | disclosed |
| US-4713452-A | Process for preparation of azetidinone derivatives | OTSUKA KAGAKU KABUSHIKI KAISHA (JP) | 1987-12-15 | — | — | US | disclosed |
| US-4087444-A | Amides as ovulation inhibitors | ELI LILLY AND COMPANY (US) | 1978-05-02 | — | — | US | disclosed |
| US-4022891-A | Novel 1α,24-dihydroxycholecalciferol compositions, novel precursors thereof, and processes for preparing them | TEIJIN LIMITED (JA) | 1977-05-10 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090176999-A1 | Process for producing hexahydrofurofuranol derivative | DHFR, DHPS, CYP4B1 | HSP90AA1 4204/4885TLR9 3486/4885ALOX15 1361/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.