SCHEMBL1802807

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL1801163	0.86	DPP4 (0.34)	DPP4ALDH1A1LMNARAB9ATSHR
	SCHEMBL1801224	0.83	RAB9A (0.50)	RIPK1PKMMAPTKDM4EALDH1A1
	SCHEMBL1802160	0.83	ALDH1A1 (0.47)	RIPK1PKMMAPTKDM4EALDH1A1
	SCHEMBL1802840	0.82	ALDH1A1 (0.47)	RIPK1MAPTKDM4EALDH1A1POLB
	SCHEMBL5156459	0.79	ALDH1A1 (0.48)	RIPK1PKMKDM4EALDH1A1CYP2C9
	SCHEMBL1800419	0.78	CCR5 (0.37)	RIPK1PKMALDH1A1
	SCHEMBL1798596	0.78	SMN1; SMN2 (0.49)	MAPTKDM4EALDH1A1KMT2ALMNA
	SCHEMBL1802733	0.78	RIPK1 (0.54)	RIPK1KDM4EALDH1A1CYP1A2POLB
	SCHEMBL1804135	0.77	RIPK1 (0.46)	RIPK1MAPTKDM4EALDH1A1CYP2D6
	SCHEMBL1800533	0.77	ALDH1A1 (0.47)	RIPK1MAPTKDM4EALDH1A1POLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.