Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALKBH5 | Q6P6C2 | 1/20 | 0.39 |
| ▸ | FTO | Q9C0B1 | 1/20 | 0.39 |
| ▸ | IMPDH2 | P12268 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | MAOA | P21397 | 3/20 | 0.37 |
| ▸ | CDC7 | O00311 | 1/20 | 0.35 |
| ▸ | CDK2 | P24941 | 1/20 | 0.35 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.35 |
| ▸ | ENPP3 | O14638 | 1/20 | 0.35 |
| ▸ | CA1 | P00915 | 2/20 | 0.34 |
| ▸ | CA2 | P00918 | 2/20 | 0.34 |
| ▸ | G6PD | P11413 | 1/20 | 0.34 |
| ▸ | BRD4 | O60885 | 1/20 | 0.33 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.33 |
| ▸ | EGFR | P00533 | 1/20 | 0.33 |
| ▸ | SRC | P12931 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | PTPN7 | P35236 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18030969 | 0.88 | EGFR (0.40) | ALKBH5FTOIMPDH2L3MBTL1MEN1 | |
| SCHEMBL16441272 | 0.85 | CASP3 (0.38) | ALKBH5FTOL3MBTL1MEN1KMT2A | |
| SCHEMBL18055746 | 0.85 | ALKBH5 (0.42) | ALKBH5FTOIMPDH2L3MBTL1KMT2A | |
| SCHEMBL17032702 | 0.82 | ALKBH5 (0.58) | ALKBH5FTOIMPDH2L3MBTL1MEN1 | |
| SCHEMBL17034482 | 0.80 | ALKBH5 (0.42) | ALKBH5FTOIMPDH2L3MBTL1MAOA | |
| SCHEMBL18030923 | 0.80 | L3MBTL1 (0.41) | L3MBTL1MEN1KMT2ACDC7CDK2 | |
| SCHEMBL18030921 | 0.80 | IMPDH2 (0.46) | ALKBH5FTOIMPDH2MAOACA1 | |
| SCHEMBL17032695 | 0.79 | GPR3 (0.57) | IMPDH2L3MBTL1MEN1KMT2ATLR9 | |
| SCHEMBL18030918 | 0.79 | L3MBTL1 (0.40) | IMPDH2L3MBTL1MEN1KMT2AMAOA | |
| SCHEMBL18030960 | 0.78 | L3MBTL1 (0.37) | ALKBH5FTOIMPDH2L3MBTL1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3061759-B1 | NITRILE SUBSTITUTED DIBENZOFURANS | IDEMITSU KOSAN CO (JP) | 2019-12-25 | — | — | EP | disclosed |
| EP-3119770-B1 | NEW DIBENZOFURANS AND DIBENZOTHIOPHENES | IDEMITSU KOSAN CO (JP) | 2018-05-02 | — | — | EP | disclosed |
| US-20170098781-A1 | NEW DIBENZOFURANS AND DIBENZOTHIOPHENES | IDEMITSU KOSAN CO., LTD. (JP) | 2017-04-06 | — | — | US | disclosed |
| US-20160248026-A1 | NITRILE SUBSTITUTED DIBENZOFURANS | IDEMITSU KOSAN CO., LTD. (JP) | 2016-08-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170098781-A1 | NEW DIBENZOFURANS AND DIBENZOTHIOPHENES | DBF4, DDT, SLC43A3 | ALKBH5 1111/4885FTO 509/4885IMPDH2 1250/4885 |
| US-20160248026-A1 | NITRILE SUBSTITUTED DIBENZOFURANS | DBF4, NXF1, NCF1 | ALKBH5 601/4885FTO 426/4885IMPDH2 2051/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.