Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.45 |
| ▸ | MEN1 | O00255 | 3/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 14/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 14/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 5/20 | 0.40 |
| ▸ | CLK4 | Q9HAZ1 | 2/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | USP2 | O75604 | 9/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 5/20 | 0.38 |
| ▸ | CASP1 | P29466 | 2/20 | 0.38 |
| ▸ | CASP7 | P55210 | 2/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.38 |
| ▸ | TSHR | P16473 | 6/20 | 0.37 |
| ▸ | HPGD | P15428 | 2/20 | 0.37 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.37 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1803012 | 0.76 | ALDH1A1 (0.53) | ALDH1A1MEN1KMT2ACYP1A2CYP3A4 | |
| SCHEMBL12620394 | 0.73 | FERMT2 (0.45) | ALDH1A1MEN1KMT2ACYP1A2CYP3A4 | |
| SCHEMBL12620389 | 0.71 | MAPK8 (0.39) | ALDH1A1MEN1KMT2ACYP1A2CYP3A4 | |
| SCHEMBL12620442 | 0.69 | ALDH1A1 (0.41) | ALDH1A1MEN1KMT2ACYP1A2CYP3A4 | |
| SCHEMBL1806470 | 0.68 | MERTK (0.60) | ALDH1A1MEN1KMT2ACYP1A2CYP3A4 | |
| SCHEMBL3977514 | 0.67 | ALDH1A1 (0.57) | ALDH1A1MEN1KMT2ACYP1A2CYP3A4 | |
| SCHEMBL11658602 | 0.66 | ADRA1A (0.56) | ALDH1A1MEN1KMT2ACYP1A2CYP3A4 | |
| SCHEMBL4197005 | 0.66 | CYP1A2 (0.66) | ALDH1A1CYP1A2CYP2C19L3MBTL1MAPK1 | |
| SCHEMBL13530264 | 0.66 | DCK (0.52) | ALDH1A1MEN1KMT2ACYP1A2CYP3A4 | |
| SCHEMBL8864442 | 0.65 | ALDH1A1 (1.00) | ALDH1A1MEN1KMT2AL3MBTL1MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110105455-A1 | PHENOXY-SUBSTITUTED PYRIMIDINES AS OPIOID RECEPTOR MODULATORS | JANSSEN PHARMACEUTICA, NV (BE) | 2011-05-05 | — | — | US | disclosed |
| WO-2011053701-A1 | PHENOXY-SUBSTITUTED PYRIMIDINES AS OPIOID RECEPTOR MODULATORS | JANSSEN PHARMACEUTICA NV (BE) | 2011-05-05 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110105455-A1 | PHENOXY-SUBSTITUTED PYRIMIDINES AS OPIOID RECEPTOR MODULATORS | OPRK1, OPRL1, OPRM1 | ALDH1A1 590/4885MEN1 4868/4885KMT2A 1602/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.