SCHEMBL180578

SCHEMBL180578

CCCCCCCCCCCCCCCCCCC(=Cc1cc(C(C)(C)C)c(O)c(C(C)(C)C)c1)C(=O)O

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GABBR2 O75899 2/20 0.47
GABBR1 Q9UBS5 2/20 0.47
HMGCR P04035 2/20 0.45
NR1I2 O75469 1/20 0.45
PTGES O14684 1/20 0.44
ALOX5 P09917 1/20 0.44
PPARG P37231 1/20 0.44
EGFR P00533 1/20 0.43
APEX1 P27695 3/20 0.42
KMT2A Q03164 4/20 0.42
LMNA P02545 3/20 0.42
RECQL P46063 3/20 0.42
MEN1 O00255 3/20 0.42
CYP3A4 P08684 3/20 0.42
MAPT P10636 3/20 0.42
TSHR P16473 3/20 0.42
BLM P54132 3/20 0.42
SMN1; SMN2 Q16637 3/20 0.42
HSD17B10 Q99714 3/20 0.42
GAA P10253 2/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5847331 0.99 GABBR2 (0.48) GABBR2GABBR1HMGCRNR1I2PTGES
SCHEMBL699097 0.94 GABBR2 (0.51) GABBR2GABBR1HMGCRNR1I2ALOX5
SCHEMBL10682355 0.89 GABBR2 (0.51) GABBR2GABBR1HMGCRNR1I2EGFR
SCHEMBL9315119 0.87 GABBR2 (0.45) GABBR2GABBR1HMGCRNR1I2EGFR
SCHEMBL2335027 0.86 GABBR2 (0.44) GABBR2GABBR1HMGCRNR1I2ALOX5
SCHEMBL5710763 0.85 GABBR2 (0.48) GABBR2GABBR1HMGCRNR1I2ALOX5
SCHEMBL6917057 0.83 HMGCR (0.47) GABBR2GABBR1HMGCRNR1I2ALOX5
SCHEMBL11096689 0.83 GABBR2 (0.51) GABBR2GABBR1HMGCRNR1I2EGFR
SCHEMBL11096685 0.83 GABBR2 (0.51) GABBR2GABBR1HMGCRNR1I2EGFR
SCHEMBL10967937 0.83 GABBR2 (0.54) GABBR2GABBR1HMGCRNR1I2EGFR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 503 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3378506-B1 DRUG RELEASING COATINGS FOR MEDICAL DEVICES LUTONIX INC (US) 2023-06-07 EP claimed
EP-1844761-B1 Cosmetic or pharmaceutical composition comprising a condensation polymer, cosmetic treatment method employing said composition, said condensation polymer and preparation method OREAL (FR) 2010-05-19 EP claimed
EP-1673413-B1 HIGH TEMPERATURE STABILIZATION OF UV SYSTEMS SARTOMER TECHNOLOGY CO INC (US) 2007-02-14 EP claimed
US-12637557-B2 High crystalline olefin polymer for high speed spinning W.R. GRACE & CO.-CONN. (US) 2026-05-26 US disclosed
US-12617984-B2 Hydrophilic hotmelt adhesive THE PROCTER & GAMBLE COMPANY (US) 2026-05-05 US disclosed
US-12570785-B2 Thermoplastic polyurethane resin elastomers MITSUBISHI CHEMICAL CORPORATION (JP) 2026-03-10 US disclosed
US-20260008875-A1 ETHYLENE-BASED POLYMER WITH REVERSIBLE CROSSLINKER DOW GLOBAL TECHNOLOGIES LLC (US) 2026-01-08 US disclosed
US-20260008879-A1 POLAR ETHYLENE-BASED POLYMER WITH REVERSIBLE CROSSLINKNER DOW GLOBAL TECHNOLOGIES LLC (US) 2026-01-08 US disclosed
US-20260008896-A1 REVERSIBLE CROSSLINKED FOAM ARTICLE AND PROCESS DOW GLOBAL TECHNOLOGIES LLC (US) 2026-01-08 US disclosed
EP-4259699-B1 HIGH CRYSTALLINE OLEFIN POLYMER FOR HIGH SPEED SPINNING GRACE W R & CO (US) 2025-10-22 EP disclosed
EP-3781105-B1 ABSORBENT ARTICLE COMPRISING AN ADHESIVE COMPOSITION PROCTER & GAMBLE (US) 2025-08-13 EP disclosed
US-20060199905-A1 Interpolymers of ethylene/a-olefins blends and profiles and gaskets made therefrom DOW GLOBAL TECHNOLOGIES INC. (US) 2006-09-07 US disclosed
US-20060199884-A1 Anti-blocking compositions comprising interpolymers of ethylene/alpha-olefins DOW GLOBAL TECHNOLOGIES INC. (US) 2006-09-07 US disclosed
US-20060199887-A1 Filled polymer compositions made from interpolymers of ethylene/a-olefins and uses thereof DOW GLOBAL TECHNOLOGIES INC. (US) 2006-09-07 US disclosed
US-20050250907-A1 Dispersant or coatability improver SANYO CHEMICAL INDUSTRIES LTD., (JP) 2005-11-10 US disclosed
EP-1579907-A2 Dispersant or coatability improver SANYO CHEMICAL INDUSTRIES, LTD. (JP) 2005-09-28 EP disclosed
US-20050009967-A1 Phosphite stabilizers and methods to preparation and polymer composition thereof CROMPTON CORPORATION 2005-01-13 US disclosed
WO-2004111158-A1 PHOSPHITE STABILIZERS AND METHODS TO PREPARATION AND POLYMER COMPOSITION THEREOF CHEMTURA CORPORATION (US) 2004-12-23 WO disclosed
WO-2004108735-A2 POLYMER COMPOSITIONS CONTAINING STABILIZER COMPOUNDS COMPRISING TRICYCLODECILMETHYL GROUPS CHEMTURA CORPORATION (US) 2004-12-16 WO disclosed
US-20040249030-A1 Polymer compositions containing stabilizer compounds comprising tricyclodecylmethyl groups ADDIVANT USA, LLC 2004-12-09 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260008875-A1 ETHYLENE-BASED POLYMER WITH REVERSIBLE CROSSLINKER CLPTM1L, LCP1, CLPTM1 GABBR2 3516/4885GABBR1 3590/4885HMGCR 3437/4885
US-12570785-B2 Thermoplastic polyurethane resin elastomers PUF60, INTS9, ADH1C GABBR2 1598/4885GABBR1 2043/4885HMGCR 1650/4885
US-12637557-B2 High crystalline olefin polymer for high speed spinning DYRK1B, DYRK3, TARDBP GABBR2 4806/4885GABBR1 4654/4885HMGCR 2761/4885
US-20050009967-A1 Phosphite stabilizers and methods to preparation and polymer composition thereof PHOSPHO1, OR51E2, CDIPT GABBR2 2559/4885GABBR1 3007/4885HMGCR 2554/4885
US-12617984-B2 Hydrophilic hotmelt adhesive EPCAM, PMS2, L1CAM GABBR2 4475/4885GABBR1 4046/4885HMGCR 3315/4885
US-20260008896-A1 REVERSIBLE CROSSLINKED FOAM ARTICLE AND PROCESS PIEZO1, AIFM2, PTDSS1 GABBR2 3973/4885GABBR1 3353/4885HMGCR 3546/4885
US-20260008879-A1 POLAR ETHYLENE-BASED POLYMER WITH REVERSIBLE CROSSLINKNER EEA1, EED, ELP1 GABBR2 3276/4885GABBR1 3490/4885HMGCR 3430/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.