Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 5/20 | 0.43 |
| ▸ | MEN1 | O00255 | 7/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.40 |
| ▸ | POLB | P06746 | 3/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.40 |
| ▸ | NPC1 | O15118 | 2/20 | 0.40 |
| ▸ | RAB9A | P51151 | 2/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.40 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27498738 | 0.90 | LMNA (0.49) | LMNAMEN1KMT2APOLBKDM4E | |
| SCHEMBL18650 | 0.86 | LMNA (0.45) | LMNAMEN1KMT2APOLBKDM4E | |
| SCHEMBL9875164 | 0.85 | KDM4E (0.50) | LMNAMEN1KMT2APOLBKDM4E | |
| SCHEMBL12140572 | 0.84 | LMNA (0.45) | LMNAMEN1KMT2APOLBKDM4E | |
| SCHEMBL19839917 | 0.84 | KDM4E (0.49) | LMNAMEN1KMT2APOLBKDM4E | |
| SCHEMBL6522997 | 0.81 | OPRM1 (0.56) | LMNAMEN1KMT2APOLBNPC1 | |
| SCHEMBL2150274 | 0.81 | LMNA (0.43) | LMNAMEN1KMT2APOLBKDM4E | |
| SCHEMBL34475790 | 0.80 | SMN1; SMN2 (0.46) | LMNAMEN1KMT2APOLBKDM4E | |
| SCHEMBL18063140 | 0.79 | KDM4E (0.45) | LMNAMEN1KMT2APOLBKDM4E | |
| SCHEMBL18063245 | 0.78 | CYP2C19 (0.47) | LMNAMEN1KMT2AKDM4EDDB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170283530-A1 | CATALYST COMPONENT FOR OLEFIN POLYMERIZATION AND APPLICATION THEREOF | BEIJING LIHE TECH LTD (CN) | 2017-10-05 | — | — | US | claimed |
| US-20160272733-A1 | CATALYST COMPONENT FOR OLEFIN POLYMERIZATION AND APPLICATION THEREOF | BEIJING LIHE TECHNOLOGY LTD. (CN) | 2016-09-22 | — | — | US | claimed |
| US-20190169328-A1 | OLEFIN POLYMERIZATION CATALYST CARRIER, SOLID CATALYST COMPONENT AND USE THEREOF | RENQIU LIHE TECH LTD (CN) | 2019-06-06 | — | — | US | disclosed |
| US-10208146-B2 | Catalyst component for olefin polymerization and application thereof | BEIJING LIHE TECHNOLOGY LTD. (CN) | 2019-02-19 | — | — | US | disclosed |
| US-20170355792-A1 | OLEFIN POLYMERIZATION CATALYST CARRIER, SOLID CATALYST COMPONENT AND USE THEREOF | RENQIU LIHE TECH LTD (CN) | 2017-12-14 | — | — | US | disclosed |
| US-20170283530-A1 | CATALYST COMPONENT FOR OLEFIN POLYMERIZATION AND APPLICATION THEREOF | BEIJING LIHE TECH LTD (CN) | 2017-10-05 | — | — | US | disclosed |
| US-20160272733-A1 | CATALYST COMPONENT FOR OLEFIN POLYMERIZATION AND APPLICATION THEREOF | BEIJING LIHE TECHNOLOGY LTD. (CN) | 2016-09-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10208146-B2 | Catalyst component for olefin polymerization and application thereof | TEC, ETFA, TECR | LMNA 4452/4885MEN1 4097/4885KMT2A 2451/4885 |
| US-20190169328-A1 | OLEFIN POLYMERIZATION CATALYST CARRIER, SOLID CATALYST COMPONENT AND USE THEREOF | COG2, GTF2I, POF1B | LMNA 2302/4885MEN1 452/4885KMT2A 2142/4885 |
| US-20170283530-A1 | CATALYST COMPONENT FOR OLEFIN POLYMERIZATION AND APPLICATION THEREOF | TEC, ETFA, TECR | LMNA 4452/4885MEN1 4097/4885KMT2A 2451/4885 |
| US-20170355792-A1 | OLEFIN POLYMERIZATION CATALYST CARRIER, SOLID CATALYST COMPONENT AND USE THEREOF | COG2, COG7, COG4 | LMNA 3701/4885MEN1 2096/4885KMT2A 2597/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.