SCHEMBL1808281

SCHEMBL1808281

C1CC2(NC34CCC(CC3)C4)CCC1C2

nearest known ligand 0.33

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
GRIN2D O15399 1/20 0.33
GRIN3B O60391 1/20 0.33
GRIN1 Q05586 1/20 0.33
GRIN2A Q12879 1/20 0.33
GRIN2B Q13224 1/20 0.33
GRIN2C Q14957 1/20 0.33
GRIN3A Q8TCU5 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2909470 0.77
SCHEMBL15022961 0.77
Hydrochloric Acid SCHEMBL7309579 0.75
SCHEMBL3082239 0.71 EPHX2 (0.60)
SCHEMBL3072038 0.71 EPHX2 (0.33)
SCHEMBL24940204 0.71 GRIN2D (0.32) GRIN2DGRIN3BGRIN1GRIN2AGRIN2B
SCHEMBL3079023 0.71 EPHX2 (0.43)
SCHEMBL3071718 0.71 EPHX2 (0.43)
SCHEMBL10012499 0.71
SCHEMBL3068816 0.71 EPHX2 (0.60)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11687003-B2 Negative resist pattern-forming method, and composition for upper layer film formation JSR CORPORATION (JP) 2023-06-27 US disclosed
US-20190004426-A1 NEGATIVE RESIST PATTERN-FORMING METHOD, AND COMPOSITION FOR UPPER LAYER FILM FORMATION JSR CORPORATION (JP) 2019-01-03 US disclosed
US-10130634-B2 Therapeutic agent for ophthalmic disease MITSUBISHI TANABE PHARMA CORPORATION (JP) 2018-11-20 US disclosed
US-10073344-B2 Negative resist pattern-forming method, and composition for upper layer film formation JSR CORPORATION (JP) 2018-09-11 US disclosed
US-20160299432-A1 NEGATIVE RESIST PATTERN-FORMING METHOD, AND COMPOSITION FOR UPPER LAYER FILM FORMATION JSR CORPORATION (JP) 2016-10-13 US disclosed
US-20160193217-A1 THERAPEUTIC AGENT FOR OPHTHALMIC DISEASE MITSUBISHI TANABE PHARMA CORPORATION (JP) 2016-07-07 US disclosed
US-8957212-B2 Photobase generator WAKO PURE CHEMICAL INDUSTRIES, LTD. (JP) 2015-02-17 US disclosed
EP-2368875-B1 PHOTOBASE GENERATOR WAKO PURE CHEM IND LTD (JP) 2014-09-03 EP disclosed
EP-1801108-B9 MORPHOLINE COMPOUNDS FOR THE TREATMENT OF INFLAMMATIONS MITSUBISHI TANABE PHARMA CORP (JP) 2013-11-20 EP disclosed
EP-1801108-B1 MORPHOLINE COMPOUNDS FOR THE TREATMENT OF INFLAMMATIONS MITSUBISHI TANABE PHARMA CORP (JP) 2012-11-14 EP disclosed
US-8198487-B2 Method for lithium exchange reactions LONZA AG (CH) 2012-06-12 US disclosed
US-20110233048-A1 PHOTOBASE GENERATOR WAKO PURE CHEMICAL INDUSTRIES, LTD. (JP) 2011-09-29 US disclosed
EP-2368875-A1 PHOTOBASE GENERATOR Wako Pure Chemical Industries, Ltd. (JP) 2011-09-28 EP disclosed
US-7935700-B2 Morpholine compound MITSUBISHI TANABE PHARMA CORPORATION (JP) 2011-05-03 US disclosed
EP-2109616-B1 METHOD FOR LITHIUM EXCHANGE REACTIONS LONZA AG (CH) 2010-08-25 EP disclosed
US-20100113839-A1 METHOD FOR LITHIUM EXCHANGE REACTIONS LONZA AG (CH) 2010-05-06 US disclosed
EP-2109616-A1 METHOD FOR LITHIUM EXCHANGE REACTIONS LONZA AG (CH) 2009-10-21 EP disclosed
WO-2008095646-A1 METHOD FOR LITHIUM EXCHANGE REACTIONS LONZA AG (CH) 2008-08-14 WO disclosed
US-20070265257-A1 Morpholine Compound MITSUBISHI PHARMA CORPORATION (JP) 2007-11-15 US disclosed
EP-1801108-A1 MORPHOLINE COMPOUND Mitsubishi Pharma Corporation (JP) 2007-06-27 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110233048-A1 PHOTOBASE GENERATOR CYBA, CRY1, GNB1 GRIN2D 2293/4885GRIN3B 1831/4885GRIN1 1294/4885
US-10130634-B2 Therapeutic agent for ophthalmic disease MITF, UACA, VEGFA GRIN2D 4092/4885GRIN3B 3525/4885GRIN1 2003/4885
US-20160193217-A1 THERAPEUTIC AGENT FOR OPHTHALMIC DISEASE MITF, UACA, VEGFA GRIN2D 4092/4885GRIN3B 3525/4885GRIN1 2003/4885
US-20070265257-A1 Morpholine Compound CCR3, CCR1, CCR4 GRIN2D 1925/4885GRIN3B 391/4885GRIN1 910/4885
US-20100113839-A1 METHOD FOR LITHIUM EXCHANGE REACTIONS SLC6A5, SLC6A9, SLC6A6 GRIN2D 725/4885GRIN3B 311/4885GRIN1 743/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.