Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS1 | P23219 | 3/20 | 0.41 |
| ▸ | PTGS2 | P35354 | 4/20 | 0.40 |
| ▸ | MMP2 | P08253 | 2/20 | 0.39 |
| ▸ | MMP9 | P14780 | 2/20 | 0.39 |
| ▸ | MMP8 | P22894 | 2/20 | 0.39 |
| ▸ | MMP12 | P39900 | 2/20 | 0.39 |
| ▸ | MMP13 | P45452 | 2/20 | 0.39 |
| ▸ | MMP14 | P50281 | 2/20 | 0.39 |
| ▸ | MMP16 | P51512 | 2/20 | 0.39 |
| ▸ | MMP3 | P08254 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 3/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | CXCL8 | P10145 | 1/20 | 0.38 |
| ▸ | MMP1 | P03956 | 1/20 | 0.38 |
| ▸ | ATM | Q13315 | 2/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18113061 | 0.85 | ATM (0.37) | PTGS1GAAALDH1A1MEN1LMNA | |
| SCHEMBL19895797 | 0.85 | TDP1 (0.41) | MMP8GAAALDH1A1MEN1LMNA | |
| SCHEMBL6713912 | 0.79 | CA12 (0.53) | PTGS1PTGS2MMP2MMP9MMP8 | |
| SCHEMBL6723569 | 0.79 | CA12 (0.53) | PTGS1PTGS2MMP2MMP9MMP8 | |
| SCHEMBL2209026 | 0.75 | PTGS2 (0.44) | PTGS1PTGS2MMP2MMP9MMP8 | |
| SCHEMBL9235115 | 0.72 | SIRT1 (0.47) | PTGS1PTGS2MMP2MMP9MMP8 | |
| SCHEMBL2204495 | 0.72 | PTGS2 (0.56) | PTGS1PTGS2MMP2MMP9MMP8 | |
| SCHEMBL16556233 | 0.71 | MMP2 (0.41) | PTGS1PTGS2MMP2MMP9MMP8 | |
| SCHEMBL9419835 | 0.71 | MEN1 (0.49) | PTGS1PTGS2MMP2MMP9MMP8 | |
| SCHEMBL18797642 | 0.70 | PTGS2 (0.50) | PTGS1PTGS2MMP2MMP9MMP8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3277736-A1 | CATALYST COMPONENTS FOR THE POLYMERIZATION OF OLEFINS | Basell Poliolefine Italia S.r.l. (IT) | 2018-02-07 | — | — | EP | disclosed |
| WO-2016156473-A1 | CATALYST COMPONENTS FOR THE POLYMERIZATION OF OLEFINS | BASELL POLIOLEFINE ITALIA S.R.L. (IT) | 2016-10-06 | — | — | WO | disclosed |