SCHEMBL18130068

SCHEMBL18130068

[N-]=[N+]=Nc1ccc(/C=C/c2cc(O)c(O)c(O)c2)cc1

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ PTGS2 P35354 1/20 0.47
▸ LCK P06239 3/20 0.45
▸ CA1 P00915 2/20 0.44
▸ CA2 P00918 2/20 0.44
▸ CA5A P35218 2/20 0.44
▸ CA9 Q16790 2/20 0.44
▸ CA5B Q9Y2D0 2/20 0.44
▸ NQO2 P16083 3/20 0.44
▸ POLB P06746 3/20 0.43
▸ BLM P54132 3/20 0.43
▸ L3MBTL1 Q9Y468 3/20 0.43
▸ TP53 P04637 3/20 0.43
▸ ALOX12 P18054 2/20 0.43
▸ CYP3A4 P08684 2/20 0.43
▸ GFER P55789 2/20 0.43
▸ ALOX15 P16050 2/20 0.43
▸ HSD17B10 Q99714 2/20 0.43
▸ KDM4E B2RXH2 2/20 0.43
▸ MEN1 O00255 2/20 0.43
▸ ALDH1A1 P00352 2/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18130069 1.00 PTGS2 (0.47) PTGS2LCKCA1CA2CA5A
SCHEMBL18130090 0.89 LCK (0.61) LCKCA1CA2CA5ACA9
SCHEMBL18130091 0.89 LCK (0.61) LCKCA1CA2CA5ACA9
SCHEMBL18130124 0.86 PTGS1 (0.57) PTGS2LCKCA1CA2CA5A
SCHEMBL17826850 0.86 PTGS1 (0.57) PTGS2LCKCA1CA2CA5A
SCHEMBL23854165 0.84 CA1 (0.47) PTGS2CA1CA2CA5ACA9
SCHEMBL13882617 0.84 CA1 (0.47) PTGS2CA1CA2CA5ACA9
SCHEMBL18130122 0.83 NQO2 (0.48) PTGS2LCKCA1CA2CA5A
SCHEMBL18130123 0.83 NQO2 (0.48) PTGS2LCKCA1CA2CA5A
SCHEMBL24211777 0.76 CYP19A1 (0.48) CA1CA2CA5ACA9CA5B

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3280402-B1 TOLAN COMPOUNDS FOR PROMOTING WOUND HEALING BIOMENDICS LLC (US) 2024-06-05 — — EP disclosed
US-11786481-B2 Formulation and process for modulating wound healing BioMendics, LLC (US) 2023-10-17 — — US disclosed
US-20210228501-A1 Formulation and Process for Modulating Wound Healing BioMendics, LLC (US) 2021-07-29 — — US disclosed
US-10426742-B2 Formulation and process for modulating wound healing BioMendics, LLC (US) 2019-10-01 — — US disclosed
US-20190022029-A1 Formulation and Process for Modulating Wound Healing BioMendics, LLC (US) 2019-01-24 — — US disclosed
US-20160296477-A1 Formulation and Process for Modulating Wound Healing BioMendics, LLC (US) 2016-10-13 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11786481-B2 Formulation and process for modulating wound healing SQSTM1, ATG7, TFEB PTGS2 2804/4885LCK 4119/4885CA1 4801/4885
US-20160296477-A1 Formulation and Process for Modulating Wound Healing SQSTM1, ATG7, TFEB PTGS2 2761/4885LCK 4216/4885CA1 4793/4885
US-20210228501-A1 Formulation and Process for Modulating Wound Healing ATG7, SQSTM1, ATF4 PTGS2 2688/4885LCK 4007/4885CA1 4803/4885
US-10426742-B2 Formulation and process for modulating wound healing SQSTM1, ATG7, TFEB PTGS2 2804/4885LCK 4119/4885CA1 4801/4885
US-20190022029-A1 Formulation and Process for Modulating Wound Healing SQSTM1, ATG7, TFEB PTGS2 2804/4885LCK 4119/4885CA1 4801/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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