Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC6 | Q9UBN7 | 8/20 | 0.47 |
| ▸ | HDAC3 | O15379 | 7/20 | 0.47 |
| ▸ | HDAC4 | P56524 | 7/20 | 0.47 |
| ▸ | HDAC1 | Q13547 | 7/20 | 0.47 |
| ▸ | HDAC7 | Q8WUI4 | 7/20 | 0.47 |
| ▸ | HDAC2 | Q92769 | 7/20 | 0.47 |
| ▸ | HDAC10 | Q969S8 | 7/20 | 0.47 |
| ▸ | HDAC11 | Q96DB2 | 7/20 | 0.47 |
| ▸ | HDAC8 | Q9BY41 | 7/20 | 0.47 |
| ▸ | HDAC9 | Q9UKV0 | 7/20 | 0.47 |
| ▸ | HDAC5 | Q9UQL6 | 7/20 | 0.47 |
| ▸ | MAP2K1 | Q02750 | 5/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.41 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9703918 | 0.83 | HDAC3 (0.47) | HDAC6HDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL6295923 | 0.77 | MAP2K1 (0.55) | HDAC6HDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL7255678 | 0.77 | HTT (0.62) | MAPTKDM4EALDH1A1HPGDTSHR | |
| SCHEMBL28893760 | 0.75 | NPC1 (0.65) | HDAC6HDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL27388239 | 0.75 | KDM4E (0.50) | MAPTSIRT1BCAT2KDM4EALDH1A1 | |
| SCHEMBL7114649 | 0.75 | LMNA (0.69) | HDAC6MAPTMEN1NR1I2LMNA | |
| SCHEMBL15057855 | 0.74 | HTT (0.56) | HDAC3HDAC1KDM4EALDH1A1HPGD | |
| SCHEMBL143432 | 0.73 | ALDH1A1 (0.49) | HDAC6HDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL8759237 | 0.73 | TSHR (0.50) | HDAC6HDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL4138337 | 0.73 | CTSD (0.55) | MAPTMEN1KMT2ABCAT2KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10718028-B2 | Fluorescent probes for abasic site detection | CASE WESTERN RESERVE UNIVERSITY (US) | 2020-07-21 | — | — | US | disclosed |
| US-20180127830-A1 | FLUORESCENT PROBES FOR ABASIC SITE DETECTION | CASE WESTERN RESERVE UNIVERSITY | 2018-05-10 | — | — | US | disclosed |
| WO-2016168467-A2 | FLUORESCENT PROBES FOR ABASIC SITE DETECTION | CASE WESTERN RESERVE UNIVERSITY (US) | 2016-10-20 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10718028-B2 | Fluorescent probes for abasic site detection | OGG1, UNG, AP2B1 | HDAC6 2433/4885HDAC3 2654/4885HDAC4 2387/4885 |
| US-20180127830-A1 | FLUORESCENT PROBES FOR ABASIC SITE DETECTION | OGG1, UNG, AP2B1 | HDAC6 2433/4885HDAC3 2654/4885HDAC4 2387/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.