Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPA1 | O75762 | 1/20 | 0.58 |
| ▸ | GLA | P06280 | 2/20 | 0.52 |
| ▸ | MEN1 | O00255 | 5/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.47 |
| ▸ | MAPT | P10636 | 5/20 | 0.47 |
| ▸ | RAB9A | P51151 | 4/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.47 |
| ▸ | PADI4 | Q9UM07 | 2/20 | 0.46 |
| ▸ | ASAH1 | Q13510 | 1/20 | 0.46 |
| ▸ | ALK | Q9UM73 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 3/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | PTK2B | Q14289 | 1/20 | 0.46 |
| ▸ | RELA | Q04206 | 2/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18160214 | 0.97 | GLA (0.54) | TRPA1GLAMEN1KMT2AMAPT | |
| SCHEMBL18157754 | 0.92 | RELA (0.55) | TRPA1GLAMEN1KMT2AMAPT | |
| SCHEMBL18180641 | 0.89 | MAPT (0.47) | TRPA1GLAMEN1KMT2AMAPT | |
| SCHEMBL18157755 | 0.87 | NPC1 (0.50) | GLAMEN1KMT2AMAPTRAB9A | |
| SCHEMBL28555372 | 0.87 | NPC1 (0.50) | GLAMEN1KMT2AMAPTRAB9A | |
| SCHEMBL18160186 | 0.84 | NPC1 (0.50) | GLAMEN1KMT2AMAPTRAB9A | |
| SCHEMBL18157735 | 0.84 | NPC1 (0.50) | GLAMEN1KMT2AMAPTRAB9A | |
| SCHEMBL18157739 | 0.81 | MAPT (0.49) | GLAMEN1KMT2AMAPTRAB9A | |
| SCHEMBL18160289 | 0.81 | NFE2L2 (0.55) | GLAMEN1KMT2AMAPTRAB9A | |
| SCHEMBL18157733 | 0.81 | NFE2L2 (0.55) | GLAMEN1KMT2AMAPTRAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10239834-B2 | Antibiotic sensitivity-restoring and photosensitive agents | NEW MEXICO TECH UNIVERSITY RESEARCH PARK CORPORATION (US) | 2019-03-26 | — | — | US | disclosed |
| US-20180155286-A1 | ANTIBIOTIC SENSITIVITY-RESTORING AND PHOTOSENSITIVE AGENTS | NEW MEXICO TECH UNIVERSITY RESEARCH PARK CORPORATION | 2018-06-07 | — | — | US | disclosed |
| US-20180155286-A1 | ANTIBIOTIC SENSITIVITY-RESTORING AND PHOTOSENSITIVE AGENTS | NEW MEXICO TECH UNIVERSITY RESEARCH PARK CORPORATION | 2018-06-07 | — | — | US | disclosed |
| US-9834514-B2 | Antibiotic sensitivity-restoring and photosensitive agents | NEW MEXICO TECH RESEARCH FOUNDATION (US) | 2017-12-05 | — | — | US | disclosed |
| US-9834514-B2 | Antibiotic sensitivity-restoring and photosensitive agents | NEW MEXICO TECH RESEARCH FOUNDATION (US) | 2017-12-05 | — | — | US | disclosed |
| WO-2016172193-A1 | ANTIBIOTIC SENSITIVITY-RESTORING AND PHOTOSENSITIVE AGENTS | NEW MEXICO TECH RESEARCH FOUNDATION (US) | 2016-10-27 | — | — | WO | disclosed |
| US-20160304453-A1 | ANTIBIOTIC SENSITIVITY-RESTORING AND PHOTOSENSITIVE AGENTS | NEW MEXICO TECH UNIVERSITY RESEARCH PARK CORPORATION | 2016-10-20 | — | — | US | disclosed |
| US-20160304453-A1 | ANTIBIOTIC SENSITIVITY-RESTORING AND PHOTOSENSITIVE AGENTS | NEW MEXICO TECH UNIVERSITY RESEARCH PARK CORPORATION | 2016-10-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10239834-B2 | Antibiotic sensitivity-restoring and photosensitive agents | XPA, PPOX, ALAD | TRPA1 1847/4885GLA 1020/4885MEN1 1398/4885 |
| US-20180155286-A1 | ANTIBIOTIC SENSITIVITY-RESTORING AND PHOTOSENSITIVE AGENTS | XPA, PPOX, ALAD | TRPA1 1847/4885GLA 1020/4885MEN1 1398/4885 |
| US-20160304453-A1 | ANTIBIOTIC SENSITIVITY-RESTORING AND PHOTOSENSITIVE AGENTS | XPA, PPOX, ALAD | TRPA1 1847/4885GLA 1020/4885MEN1 1398/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.