Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 3/20 | 0.38 |
| ▸ | ESR1 | P03372 | 5/20 | 0.37 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.37 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.37 |
| ▸ | PGR | P06401 | 1/20 | 0.36 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.36 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.36 |
| ▸ | HTR2A | P28223 | 1/20 | 0.36 |
| ▸ | HRH1 | P35367 | 1/20 | 0.36 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.36 |
| ▸ | ATM | Q13315 | 1/20 | 0.34 |
| ▸ | ESRRB | O95718 | 1/20 | 0.34 |
| ▸ | SNCA | P37840 | 2/20 | 0.33 |
| ▸ | CES2 | O00748 | 2/20 | 0.33 |
| ▸ | CES1 | P23141 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15364809 | 0.76 | PTGS2 (0.42) | PTGS2ESR1CYP19A1ESR2ATM | |
| SCHEMBL12294540 | 0.76 | ESR1 (0.41) | PTGS2ESR1CYP19A1ESR2ATM | |
| SCHEMBL377450 | 0.70 | ESR1 (0.42) | PTGS2ESR1CYP19A1ESR2CES2 | |
| SCHEMBL15364428 | 0.69 | PTGS2 (0.44) | PTGS2ESR1CYP19A1ESR2ATM | |
| SCHEMBL15364413 | 0.69 | ESR1 (0.45) | PTGS2ESR1CYP19A1ESR2CES2 | |
| SCHEMBL6935690 | 0.66 | ESR1 (0.42) | PTGS2ESR1CYP19A1ESR2CES2 | |
| SCHEMBL10601630 | 0.65 | ESR1 (0.50) | PTGS2ESR1CYP19A1ESR2PGR | |
| SCHEMBL15364487 | 0.64 | PTGS2 (0.47) | PTGS2ESR1CES2CES1 | |
| SCHEMBL15364433 | 0.64 | PTGS2 (0.47) | PTGS2ESR1CES2CES1 | |
| SCHEMBL19007619 | 0.64 | LMNA (0.40) | PGRADRA2AADRA2BHTR2AHRH1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9663447-B2 | Asymmetric butadiene-based charge transport compound, electrophotographic photoreceptor containing same, and image forming apparatus | S-PRINTING SOLUTION CO., LTD. (KR) | 2017-05-30 | — | — | US | disclosed |
| US-20160304437-A1 | ASYMMETRIC BUTADIENE-BASED CHARGE TRANSPORT COMPOUND, ELECTROPHOTOGRAPHIC PHOTORECEPTOR CONTAINING SAME, AND IMAGE FORMING APPARATUS | SAMSUNG ELECTRONICS CO., LTD. (KR) | 2016-10-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160304437-A1 | ASYMMETRIC BUTADIENE-BASED CHARGE TRANSPORT COMPOUND, ELECTROPHOTOGRAPHIC PHOTORECEPTOR CONTAINING SAME, AND IMAGE FORMING APPARATUS | ALDH1A2, USE1, SLC9A1 | PTGS2 2881/4885ESR1 2879/4885CYP19A1 1463/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.