Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | WDR5 | P61964 | 1/20 | 0.44 |
| ▸ | CNR1 | P21554 | 6/20 | 0.38 |
| ▸ | CNR2 | P34972 | 3/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.37 |
| ▸ | MEN1 | O00255 | 3/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.36 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 2/20 | 0.35 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.35 |
| ▸ | MARS1 | P56192 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.34 |
| ▸ | ATM | Q13315 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | PKM | P14618 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18166443 | 0.92 | MARS1 (0.43) | WDR5CNR1CNR2KMT2AMEN1 | |
| SCHEMBL18166449 | 0.92 | ACKR3 (0.38) | WDR5MAPK1 | |
| SCHEMBL10243066 | 0.88 | WDR5 (0.49) | WDR5CNR1CNR2MAPK1ADORA2A | |
| SCHEMBL18166359 | 0.86 | P2RX3 (0.40) | KMT2AMAPK1POLBMAPTKDM4E | |
| SCHEMBL18166354 | 0.86 | KMT2A (0.38) | WDR5KMT2AMEN1MAPK1ATM | |
| SCHEMBL18166307 | 0.86 | MARS1 (0.37) | WDR5KMT2AMEN1POLBMARS1 | |
| SCHEMBL18036449 | 0.83 | DGAT2 (0.39) | KMT2AMEN1MAPTATMNPSR1 | |
| SCHEMBL18166377 | 0.82 | KMT2A (0.44) | KMT2APOLBMAPTKDM4ENCOA1 | |
| SCHEMBL18166298 | 0.81 | P2RX3 (0.42) | — | |
| SCHEMBL10243041 | 0.79 | P2RX3 (0.44) | WDR5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2038264-B1 | TETRAZOLE-SUBSTITUTED ARYLAMIDES | HOFFMANN LA ROCHE (CH) | 2016-10-26 | — | — | EP | claimed |