Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.58 |
| ▸ | TUBB1 | Q9H4B7 | 2/20 | 0.52 |
| ▸ | GAA | P10253 | 2/20 | 0.52 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.52 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.52 |
| ▸ | TUBB | P07437 | 1/20 | 0.52 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.52 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.52 |
| ▸ | TUBA4A | P68366 | 1/20 | 0.52 |
| ▸ | TUBB4B | P68371 | 1/20 | 0.52 |
| ▸ | TUBB3 | Q13509 | 1/20 | 0.52 |
| ▸ | TUBB2A | Q13885 | 1/20 | 0.52 |
| ▸ | TUBB8 | Q3ZCM7 | 1/20 | 0.52 |
| ▸ | TUBA3E | Q6PEY2 | 1/20 | 0.52 |
| ▸ | TUBA1A | Q71U36 | 1/20 | 0.52 |
| ▸ | TUBA1C | Q9BQE3 | 1/20 | 0.52 |
| ▸ | TUBB6 | Q9BUF5 | 1/20 | 0.52 |
| ▸ | TUBB2B | Q9BVA1 | 1/20 | 0.52 |
| ▸ | CES2 | O00748 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11914196 | 0.89 | ALDH1A1 (0.46) | ALDH1A1TUBB1GAAABCG2KDM4E | |
| SCHEMBL3545138 | 0.89 | TUBB4A (0.68) | ALDH1A1TUBB1GAATUBB4ATUBB | |
| SCHEMBL18529809 | 0.87 | KMT2A (0.53) | ALDH1A1TUBB1GAAABCG2KDM4E | |
| SCHEMBL2464374 | 0.87 | HTT (0.59) | ALDH1A1GAACES2CES1MEN1 | |
| SCHEMBL25508540 | 0.86 | CES2 (0.64) | ALDH1A1GAAABCG2KDM4ECES2 | |
| SCHEMBL4818395 | 0.85 | TUBB4A (0.74) | ALDH1A1TUBB1GAATUBB4ATUBB | |
| SCHEMBL4820908 | 0.85 | CES2 (0.69) | ABCG2CES2CES1MEN1KMT2A | |
| SCHEMBL10013267 | 0.83 | ATM (0.59) | ALDH1A1TUBB1TUBB4ATUBBTUBA3C | |
| SCHEMBL4824025 | 0.82 | CYP1A2 (0.79) | ALDH1A1TUBB1GAATUBB4ATUBB | |
| 3,5-Dimethoxybenzoic Acid SCHEMBL503889 | 0.82 | RXRA (0.64) | ALDH1A1GAAABCG2KDM4ERXRA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 35 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110381941-A | SUMO-associated modified small molecule antagonists of CRMP2 and uses thereof | 代表亚利桑那大学的亚利桑那校董会 | 2019-10-25 | — | — | CN | claimed |
| CN-110381941-A | SUMO-associated modified small molecule antagonists of CRMP2 and uses thereof | 代表亚利桑那大学的亚利桑那校董会 | 2019-10-25 | — | — | CN | disclosed |
| CN-108752236-A | SHIP1 conditioning agents and relative method | 阿奎诺克斯药物（加拿大）公司 | 2018-11-06 | — | — | CN | disclosed |
| CN-105026375-B | SHIP1 modulators and methods related thereto | 阿奎诺克斯药物（加拿大）公司 | 2018-06-05 | — | — | CN | disclosed |
| CN-105026375-A | SHIP1 modulators and methods related thereto | AQUINOX PHARMACEUTICALS INC | 2015-11-04 | — | — | CN | disclosed |
| CN-102781583-B | Metathesis catalyst and process for use thereof | EXXONMOBIL CHEM PATENTS INC | 2015-07-22 | — | — | CN | disclosed |
| CN-104610230-A | Compounds for the treatment of cancer | UNIV TENNESSEE RES FOUNDATION | 2015-05-13 | — | — | CN | disclosed |
| EP-2866936-A1 | METATHESIS CATALYST AND PROCESS FOR USE THEREOF | ExxonMobil Chemical Patents Inc. (US) | 2015-05-06 | — | — | EP | disclosed |
| CN-104394987-A | Metathesis catalyst and process for use thereof | EXXONMOBIL CHEM PATENTS INC | 2015-03-04 | — | — | CN | disclosed |
| CN-102137592-B | Compounds for the treatment of cancer | UNIV TENNESSEE RES FOUNDATION (US) | 2015-01-28 | — | — | CN | disclosed |
| CN-101056846-A | Diphenylethylene compounds and uses thereof | CELGENE CORP (US) | 2007-10-17 | — | — | CN | disclosed |
| EP-1799634-A2 | DIPHENYLETHYLENE COMPOUNDS AND USES THEREOF | CELGENE CORPORATION (US) | 2007-06-27 | — | — | EP | disclosed |
| EP-1603864-A4 | DIPHENYLETHYLENE COMPOUNDS AND USES THEREOF | CELGENE CORP (US) | 2007-04-11 | — | — | EP | disclosed |
| CN-1780811-A | Diphenylethylene compounds and uses thereof | CELGENE CORP (US) | 2006-05-31 | — | — | CN | disclosed |
| WO-2006026747-A2 | DIPHENYLETHYLENE COMPOUNDS AND USES THEREOF | CELGENE CORPORATION (US) | 2006-03-09 | — | — | WO | disclosed |
| EP-1603864-A2 | DIPHENYLETHYLENE COMPOUNDS AND USES THEREOF | CELGENE CORPORATION (US) | 2005-12-14 | — | — | EP | disclosed |
| US-20050107339-A1 | Diphenylethylene compounds and uses thereof | CELGENE CORPORATION | 2005-05-19 | — | — | US | disclosed |
| US-20050014727-A1 | Diphenylethylene compounds and uses thereof | CELGENE CORPORATION | 2005-01-20 | — | — | US | disclosed |
| WO-2004078144-A2 | DIPHENYLETHYLENE COMPOUNDS AND USES THEREOF | CELGENE CORPORATION (US) | 2004-09-16 | — | — | WO | disclosed |
| US-4042587-A | PESTICIDES | BASF AKTIENGESELLSCHAFT (DT) | 1977-08-16 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050107339-A1 | Diphenylethylene compounds and uses thereof | VHL, TNF, PTGES | ALDH1A1 124/4885TUBB1 3121/4885GAA 1186/4885 |
| US-20050014727-A1 | Diphenylethylene compounds and uses thereof | VHL, TNF, PTGES | ALDH1A1 124/4885TUBB1 3121/4885GAA 1186/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.