Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.53 |
| ▸ | MEN1 | O00255 | 2/20 | 0.53 |
| ▸ | LMNA | P02545 | 1/20 | 0.53 |
| ▸ | MAPT | P10636 | 1/20 | 0.53 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.53 |
| ▸ | RAB9A | P51151 | 1/20 | 0.53 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.53 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.44 |
| ▸ | TUBB1 | Q9H4B7 | 2/20 | 0.43 |
| ▸ | GAA | P10253 | 2/20 | 0.43 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.43 |
| ▸ | TUBB | P07437 | 1/20 | 0.43 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.43 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.43 |
| ▸ | TUBA4A | P68366 | 1/20 | 0.43 |
| ▸ | TUBB4B | P68371 | 1/20 | 0.43 |
| ▸ | TUBB3 | Q13509 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1817008 | 0.87 | ALDH1A1 (0.58) | KMT2AMEN1LMNAMAPTMAPK1 | |
| SCHEMBL30655523 | 0.84 | RAB9A (0.54) | KMT2AMEN1LMNAMAPTMAPK1 | |
| SCHEMBL18529825 | 0.84 | CES2 (0.51) | KMT2AMEN1LMNAMAPTMAPK1 | |
| SCHEMBL18529835 | 0.84 | CES2 (0.61) | KMT2AMEN1LMNAMAPTMAPK1 | |
| SCHEMBL18540680 | 0.80 | ALDH1A1 (0.44) | KMT2AMEN1LMNAMAPTMAPK1 | |
| SCHEMBL1189073 | 0.80 | LMNA (0.47) | KMT2AMEN1LMNAMAPTMAPK1 | |
| SCHEMBL585918 | 0.80 | CA1 (0.50) | KMT2AMEN1LMNAMAPTMAPK1 | |
| SCHEMBL1168105 | 0.80 | HTT (0.43) | KMT2AMEN1LMNAMAPTMAPK1 | |
| SCHEMBL31032776 | 0.80 | CA1 (0.50) | KMT2AMEN1LMNAMAPTMAPK1 | |
| SCHEMBL25432683 | 0.78 | PARP1 (0.55) | KMT2AMEN1LMNAMAPTMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20190010173-A1 | COMPOSITIONS AND METHODS FOR INHIBITION OF CATHEPSINS | MATEON THERAPEUTICS, INC. (US) | 2019-01-10 | — | — | US | disclosed |
| WO-2017030983-A1 | COMPOSITIONS AND METHODS FOR INHIBITION OF CATHEPSINS | MATEON THERAPEUTICS, INC. (US) | 2017-02-23 | — | — | WO | disclosed |
| WO-2017030983-A1 | COMPOSITIONS AND METHODS FOR INHIBITION OF CATHEPSINS | MATEON THERAPEUTICS, INC. (US) | 2017-02-23 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20190010173-A1 | COMPOSITIONS AND METHODS FOR INHIBITION OF CATHEPSINS | CTSS, CTSB, CTSK | KMT2A 4800/4885MEN1 4721/4885LMNA 2264/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.