Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BTK | Q06187 | 1/20 | 0.44 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.33 |
| ▸ | ASGR1 | P07306 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.32 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.32 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.32 |
| ▸ | KDM4D | Q6B0I6 | 1/20 | 0.31 |
| ▸ | BUB1 | O43683 | 1/20 | 0.31 |
| ▸ | USP30 | Q70CQ3 | 2/20 | 0.31 |
| ▸ | ACE | P12821 | 1/20 | 0.31 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.30 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.30 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.30 |
| ▸ | JAK2 | O60674 | 1/20 | 0.30 |
| ▸ | JAK1 | P23458 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2847124 | 1.00 | BTK (0.44) | BTKHSD11B1KMT2AHSD17B10PTPN1 | |
| SCHEMBL16513085 | 1.00 | BTK (0.44) | BTKHSD11B1KMT2AHSD17B10PTPN1 | |
| SCHEMBL1663087 | 1.00 | BTK (0.44) | BTKHSD11B1KMT2AHSD17B10PTPN1 | |
| SCHEMBL23716710 | 0.92 | BTK (0.54) | BTKHSD11B1KMT2AHSD17B10ASGR1 | |
| SCHEMBL27033054 | 0.92 | BTK (0.54) | BTKHSD11B1KMT2AHSD17B10ASGR1 | |
| SCHEMBL1299115 | 0.90 | HSD11B1 (0.41) | BTKHSD11B1KMT2AHSD17B10PTPN1 | |
| SCHEMBL1344888 | 0.90 | HSD11B1 (0.41) | BTKHSD11B1KMT2AHSD17B10PTPN1 | |
| SCHEMBL1299111 | 0.90 | HSD11B1 (0.41) | BTKHSD11B1KMT2AHSD17B10PTPN1 | |
| SCHEMBL25250119 | 0.88 | HSD11B1 (0.42) | BTKHSD11B1KMT2AHSD17B10ASGR1 | |
| SCHEMBL25294971 | 0.88 | HSD11B1 (0.42) | BTKHSD11B1KMT2AHSD17B10ASGR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 40 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220281863-A1 | COMPOUNDS, COMPOSITIONS AND METHODS OF TREATING DISORDERS | REVERIE LABS INC (US) | 2022-09-08 | — | — | US | disclosed |
| WO-2021102410-A1 | NAPHTHO[2,1 -D]THIAZOLE DERIVATIVES, COMPOSITIONS THEREOF AND METHODS OF TREATING DISORDERS | REVERIE LABS, INC. (US) | 2021-05-27 | — | — | WO | disclosed |
| US-10118919-B2 | 3-substituted cyclopentylamine derivatives | MERCK PATENT GMBH (DE) | 2018-11-06 | — | — | US | disclosed |
| EP-3033339-B1 | 3-SUBSTITUTED CYCLOPENTYLAMINE DERIVATIVES | MERCK PATENT GMBH (DE) | 2018-02-28 | — | — | EP | disclosed |
| EP-3033339-B1 | 3-SUBSTITUTED CYCLOPENTYLAMINE DERIVATIVES | MERCK PATENT GMBH (DE) | 2018-02-28 | — | — | EP | disclosed |
| US-20180022738-A1 | 3-SUBSTITUTED CYCLOPENTYLAMINE DERIVATIVES | MERCK PATENT GMBH (DE) | 2018-01-25 | — | — | US | disclosed |
| US-20180022738-A1 | 3-SUBSTITUTED CYCLOPENTYLAMINE DERIVATIVES | MERCK PATENT GMBH (DE) | 2018-01-25 | — | — | US | disclosed |
| US-20180022738-A1 | 3-SUBSTITUTED CYCLOPENTYLAMINE DERIVATIVES | MERCK PATENT GMBH (DE) | 2018-01-25 | — | — | US | disclosed |
| US-9790216-B2 | 3-substituted cyclopentylamine derivatives | MERCK PATENT GMBH (DE) | 2017-10-17 | — | — | US | disclosed |
| US-9790216-B2 | 3-substituted cyclopentylamine derivatives | MERCK PATENT GMBH (DE) | 2017-10-17 | — | — | US | disclosed |
| EP-2920146-A1 | 3-AMINOCYCLOPENTANE CARBOXAMIDE DERIVATIVES | Merck Patent GmbH (DE) | 2015-09-23 | — | — | EP | disclosed |
| EP-2401268-B1 | OXYINDOLE DERIVATIVES WITH MOTILIN RECEPTOR AGONISTIC ACTIVITY | RAQUALIA PHARMA INC (JP) | 2015-07-29 | — | — | EP | disclosed |
| WO-2015022038-A1 | 3-SUBSTITUTED CYCLOPENTYLAMINE DERIVATIVES | MERCK PATENT GMBH (DE) | 2015-02-19 | — | — | WO | disclosed |
| WO-2015022038-A1 | 3-SUBSTITUTED CYCLOPENTYLAMINE DERIVATIVES | MERCK PATENT GMBH (DE) | 2015-02-19 | — | — | WO | disclosed |
| WO-2014202168-A1 | 1,3-DIAMINOCYCLOPENTANE CARBOXAMIDE DERIVATIVES | MERCK PATENT GMBH (DE) | 2014-12-24 | — | — | WO | disclosed |
| WO-2014075754-A1 | 3-AMINOCYCLOPENTANE CARBOXAMIDE DERIVATIVES | MERCK PATENT GMBH (DE) | 2014-05-22 | — | — | WO | disclosed |
| US-8697877-B2 | Oxyindole derivatives with motilin receptor agonistic activity | RAQUALIA PHARMA INC. (JP) | 2014-04-15 | — | — | US | disclosed |
| EP-2401268-A1 | OXYINDOLE DERIVATIVES WITH MOTILIN RECEPTOR AGONISTIC ACTIVITY | RaQualia Pharma Inc (JP) | 2012-01-04 | — | — | EP | disclosed |
| US-20110312933-A1 | OXYINDOLE DERIVATIVES WITH MOTILIN RECEPTOR AGONISTIC ACTIVITY | RAQUALIA PHARMA INC. (JP) | 2011-12-22 | — | — | US | disclosed |
| WO-2010098145-A1 | OXYINDOLE DERIVATIVES WITH MOTILIN RECEPTOR AGONISTIC ACTIVITY | RAQUALIA PHARMA INC. (JP) | 2010-09-02 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180022738-A1 | 3-SUBSTITUTED CYCLOPENTYLAMINE DERIVATIVES | FASN, FADS1, ACOX3 | BTK 2210/4885HSD11B1 676/4885KMT2A 2907/4885 |
| US-20110312933-A1 | OXYINDOLE DERIVATIVES WITH MOTILIN RECEPTOR AGONISTIC ACTIVITY | GPR68, GPR88, GPR52 | BTK 4361/4885HSD11B1 745/4885KMT2A 3436/4885 |
| US-10118919-B2 | 3-substituted cyclopentylamine derivatives | FASN, FADS1, ACOX3 | BTK 2210/4885HSD11B1 676/4885KMT2A 2907/4885 |
| US-20220281863-A1 | COMPOUNDS, COMPOSITIONS AND METHODS OF TREATING DISORDERS | CDK9, CDK19, CDK6 | BTK 2796/4885HSD11B1 697/4885KMT2A 1047/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.