SCHEMBL1817334

SCHEMBL1817334

OB(O)Oc1cccc2cccnc12

nearest known ligand 0.53

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 5/20 0.53
LMNA P02545 5/20 0.51
METAP2 P50579 3/20 0.51
METAP1 P53582 3/20 0.51
HDAC6 Q9UBN7 1/20 0.51
RAB9A P51151 5/20 0.50
MAPT P10636 4/20 0.50
MMP2 P08253 2/20 0.50
TSHR P16473 2/20 0.50
CHRM1 P11229 1/20 0.50
COMT P21964 1/20 0.50
ADRA1A P35348 1/20 0.50
HDAC8 Q9BY41 1/20 0.50
GAA P10253 1/20 0.50
POLB P06746 1/20 0.49
NPC1 O15118 4/20 0.49
SMN1; SMN2 Q16637 3/20 0.49
MEN1 O00255 2/20 0.49
KMT2A Q03164 2/20 0.49
HSP90AA1 P07900 2/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28755527 0.98 KDM4E (0.51) KDM4ELMNAMETAP2METAP1HDAC6
SCHEMBL7062366 0.79 RAB9A (0.55) KDM4ELMNAMETAP2METAP1HDAC6
SCHEMBL3860121 0.79 KDM4E (0.58) KDM4ELMNAMETAP2METAP1HDAC6
SCHEMBL21809385 0.78 CCR1 (0.53) KDM4ELMNAMETAP2METAP1HDAC6
SCHEMBL7066740 0.78 LMNA (0.55) KDM4ELMNAMETAP2METAP1HDAC6
SCHEMBL4386263 0.78 KDM4E (0.72) KDM4ELMNAMETAP2METAP1HDAC6
SCHEMBL4169797 0.77 METAP2 (0.55) KDM4ELMNAMETAP2METAP1HDAC6
SCHEMBL4832811 0.77 KDM4E (0.49) KDM4ELMNAMETAP2METAP1HDAC6
SCHEMBL1187034 0.77 KDM4E (0.49) KDM4ELMNAMETAP2METAP1HDAC6
Hydrochloric Acid SCHEMBL27496748 0.76 KDM4E (0.59) KDM4ELMNAMETAP2METAP1HDAC6

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20150376085-A1 ANTHRACENE COMPOUND, METHOD FOR PREPARING THE SAME, USE THEREOF AND ORGANIC LIGHT EMITTING DEVICE BOE TECHNOLOGY GROUP CO., LTD. (CN) 2015-12-31 US claimed
US-10392395-B2 Nitrogen-containing aromatic compounds and metal complexes SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2019-08-27 US disclosed
CN-109507165-A A kind of detection method of Fructose in Honey content 南京师范大学 2019-03-22 CN disclosed
EP-2493890-B1 NITROGEN-CONTAINING AROMATIC COMPOUNDS AND METAL COMPLEXES SUMITOMO CHEMICAL CO (JP) 2018-03-21 EP disclosed
CN-106458899-A Fluoranthene derivative, electronic device containing same, light-emitting element, and photoelectric conversion element 东丽株式会社 2017-02-22 CN disclosed
US-20150376085-A1 ANTHRACENE COMPOUND, METHOD FOR PREPARING THE SAME, USE THEREOF AND ORGANIC LIGHT EMITTING DEVICE BOE TECHNOLOGY GROUP CO., LTD. (CN) 2015-12-31 US disclosed
US-20120270141-A1 NITROGEN-CONTAINING AROMATIC COMPOUNDS AND METAL COMPLEXES MAX PLANCK GESELLSCHAFT ZUR FOERDERUNG DER WISSENSCHAFTEN E.V. (DE) 2012-10-25 US disclosed
CN-102666547-A Nitrogen-containing aromatic compound and metal complex SUMITOMO CHEMICAL CO 2012-09-12 CN disclosed
EP-2493890-A1 NITROGEN-CONTAINING AROMATIC COMPOUNDS AND METAL COMPLEXES Sumitomo Chemical Company, Limited (JP) 2012-09-05 EP disclosed
WO-2011052805-A1 NITROGEN-CONTAINING AROMATIC COMPOUNDS AND METAL COMPLEXES SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2011-05-05 WO disclosed
CN-1052851-C Composite rare-earth fresh cut flower preserving agent XU XINYU (CN) 2000-05-31 CN disclosed
CN-1138943-A Composite rare-earth fresh cut flower preserving agent XU XINYU (CN) 1997-01-01 CN disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20120270141-A1 NITROGEN-CONTAINING AROMATIC COMPOUNDS AND METAL COMPLEXES TYR, MT-CO2, SOD1 KDM4E 563/4885LMNA 3383/4885METAP2 2107/4885
US-10392395-B2 Nitrogen-containing aromatic compounds and metal complexes TYR, MT-CO2, SOD1 KDM4E 563/4885LMNA 3383/4885METAP2 2107/4885
US-20150376085-A1 ANTHRACENE COMPOUND, METHOD FOR PREPARING THE SAME, USE THEREOF AND ORGANIC LIGHT EMITTING DEVICE CYP2C9, AHR, AOC2 KDM4E 2434/4885LMNA 440/4885METAP2 3875/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.