SCHEMBL14040238

SCHEMBL14040238

CCCc1ccc(-c2nc(C(Cl)(Cl)Cl)nc(C(Cl)(Cl)Cl)n2)cc1

nearest known ligand 0.39

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
S1PR1 P21453 2/20 0.39
S1PR4 O95977 1/20 0.39
S1PR3 Q99500 1/20 0.39
S1PR5 Q9H228 1/20 0.39
NISCH Q9Y2I1 1/20 0.38
RAB9A P51151 5/20 0.37
NPC1 O15118 4/20 0.37
MAPT P10636 3/20 0.37
GFER P55789 1/20 0.37
SMN1; SMN2 Q16637 4/20 0.36
ALDH1A1 P00352 3/20 0.36
KDM4E B2RXH2 2/20 0.36
GAA P10253 2/20 0.36
MEN1 O00255 1/20 0.36
USP2 O75604 1/20 0.36
HPGD P15428 1/20 0.36
KMT2A Q03164 1/20 0.36
HSD17B10 Q99714 1/20 0.36
NFKB1 P19838 1/20 0.36
NFKB2 Q00653 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2833718 0.90 RAB9A (0.47) S1PR1S1PR4S1PR5NISCHRAB9A
SCHEMBL1817406 0.86 S1PR1 (0.36) S1PR1S1PR4S1PR3S1PR5NISCH
SCHEMBL2832962 0.86 TP53 (0.43) S1PR1S1PR5NISCHRAB9ANPC1
SCHEMBL3343534 0.84 TP53 (0.42) S1PR1S1PR5NISCHRAB9ANPC1
SCHEMBL3311317 0.83 L3MBTL1 (0.42) RAB9ANPC1MAPTALDH1A1KDM4E
SCHEMBL21887379 0.81 NISCH (0.47) S1PR1S1PR4S1PR3S1PR5NISCH
SCHEMBL8412982 0.81 NPC1 (0.38) RAB9ANPC1MAPTALDH1A1KDM4E
SCHEMBL765590 0.79 ADORA3 (0.38) S1PR1S1PR3ADORA3
SCHEMBL2760438 0.79 IDO1 (0.39)
SCHEMBL3310276 0.78 TP53 (0.37) NISCHRAB9ANPC1MAPTSMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1449651-B1 Polymerizable composition and lithographic printing plate precursor FUJIFILM CORP (JP) 2008-10-29 EP disclosed
EP-1832633-A1 Ink-jet recording ink set and ink-jet recording method FUJIFILM Corporation (JP) 2007-09-12 EP disclosed