Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTOR | P42345 | 1/20 | 0.38 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.37 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.37 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.37 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.37 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.37 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.37 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.37 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.36 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | TEAD1 | P28347 | 1/20 | 0.35 |
| ▸ | NAMPT | P43490 | 2/20 | 0.35 |
| ▸ | AKT2 | P31751 | 1/20 | 0.35 |
| ▸ | MGLL | Q99685 | 1/20 | 0.35 |
| ▸ | LSS | P48449 | 1/20 | 0.34 |
| ▸ | P2RX7 | Q99572 | 2/20 | 0.34 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.34 |
| ▸ | CA1 | P00915 | 1/20 | 0.34 |
| ▸ | CA2 | P00918 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18197810 | 0.87 | MLYCD (0.41) | HRH3TEAD1TRPV1 | |
| SCHEMBL14703466 | 0.83 | KCNH2 (0.45) | MTORHDAC3HDAC1HDAC2HDAC10 | |
| SCHEMBL14703438 | 0.83 | KCNH2 (0.42) | MTORHDAC3HDAC1HDAC2HDAC10 | |
| SCHEMBL18197806 | 0.82 | EPHX2 (0.41) | NAMPTTRPV1 | |
| SCHEMBL14703143 | 0.82 | KDM4E (0.46) | MTORHDAC3HDAC1HDAC2HDAC10 | |
| SCHEMBL18197821 | 0.81 | HRH3 (0.43) | HRH3ALDH1A1AKT2P2RX7TRPV1 | |
| SCHEMBL17356938 | 0.80 | MTOR (0.39) | MTORHDAC3HDAC1HDAC2HDAC10 | |
| SCHEMBL17777459 | 0.80 | CHKA (0.44) | HDAC3HDAC1HDAC2HDAC10HDAC11 | |
| SCHEMBL21832068 | 0.80 | CA1 (0.37) | MTORHDAC3HDAC1HDAC2HDAC10 | |
| SCHEMBL18197822 | 0.78 | SCN5A (0.43) | KCNH2HRH3NAMPTAKT2TRPV1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10590081-B2 | Guanidine compounds and use thereof | IMMUNOMET THERAPEUTICS INC. (US) | 2020-03-17 | — | — | US | claimed |
| EP-3288918-B1 | GUANIDINE COMPOUNDS AND USE THEREOF | IMMUNOMET THERAPEUTICS INC (US) | 2021-10-20 | — | — | EP | disclosed |
| US-20180093953-A1 | GUANIDINE COMPOUNDS AND USE THEREOF | IMMUNOMET THERAPEUTICS INC. | 2018-04-05 | — | — | US | disclosed |
| US-20180093953-A1 | GUANIDINE COMPOUNDS AND USE THEREOF | IMMUNOMET THERAPEUTICS INC. | 2018-04-05 | — | — | US | disclosed |
| WO-2016175357-A1 | GUANIDINE COMPOUNDS AND USE THEREOF | IMMUNOMET THERAPEUTICS INC. (US) | 2016-11-03 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180093953-A1 | GUANIDINE COMPOUNDS AND USE THEREOF | PC, TFAM, PCK2 | MTOR 256/4885HDAC3 889/4885HDAC1 1134/4885 |
| US-10590081-B2 | Guanidine compounds and use thereof | PC, TFAM, PCK2 | MTOR 256/4885HDAC3 889/4885HDAC1 1134/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.