Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MLYCD | O95822 | 1/20 | 0.41 |
| ▸ | PLA2G1B | P04054 | 2/20 | 0.41 |
| ▸ | ATG4B | Q9Y4P1 | 2/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.40 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.39 |
| ▸ | ALKBH5 | Q6P6C2 | 1/20 | 0.39 |
| ▸ | FTO | Q9C0B1 | 1/20 | 0.39 |
| ▸ | TEAD1 | P28347 | 2/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18197800 | 0.87 | MTOR (0.38) | HRH3TRPV1TEAD1 | |
| SCHEMBL14703426 | 0.83 | MEN1 (0.52) | MLYCDPLA2G1BATG4BNPC1PKM | |
| SCHEMBL17356937 | 0.82 | MLYCD (0.45) | MLYCDPLA2G1BATG4BNPC1PKM | |
| SCHEMBL14703352 | 0.81 | ALDH1A1 (0.45) | MLYCDPLA2G1BATG4BNPC1PKM | |
| SCHEMBL17777580 | 0.81 | HRH4 (0.51) | MLYCDPLA2G1BATG4BNPC1PKM | |
| SCHEMBL21832066 | 0.81 | CYP3A4 (0.39) | MLYCDPLA2G1BATG4BNPC1PKM | |
| SCHEMBL17356978 | 0.80 | MLYCD (0.41) | MLYCDPLA2G1BATG4BNPC1PKM | |
| SCHEMBL17777597 | 0.80 | TEAD1 (0.46) | MLYCDPLA2G1BATG4BNPC1PKM | |
| SCHEMBL18197821 | 0.79 | HRH3 (0.43) | KMT2AMEN1HRH3TRPV1TSHR | |
| SCHEMBL23935877 | 0.78 | METAP2 (0.42) | PKMKMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10590081-B2 | Guanidine compounds and use thereof | IMMUNOMET THERAPEUTICS INC. (US) | 2020-03-17 | — | — | US | claimed |
| EP-3288918-B1 | GUANIDINE COMPOUNDS AND USE THEREOF | IMMUNOMET THERAPEUTICS INC (US) | 2021-10-20 | — | — | EP | disclosed |
| US-20180093953-A1 | GUANIDINE COMPOUNDS AND USE THEREOF | IMMUNOMET THERAPEUTICS INC. | 2018-04-05 | — | — | US | disclosed |
| US-20180093953-A1 | GUANIDINE COMPOUNDS AND USE THEREOF | IMMUNOMET THERAPEUTICS INC. | 2018-04-05 | — | — | US | disclosed |
| WO-2016175357-A1 | GUANIDINE COMPOUNDS AND USE THEREOF | IMMUNOMET THERAPEUTICS INC. (US) | 2016-11-03 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180093953-A1 | GUANIDINE COMPOUNDS AND USE THEREOF | PC, TFAM, PCK2 | MLYCD 120/4885PLA2G1B 3679/4885ATG4B 3344/4885 |
| US-10590081-B2 | Guanidine compounds and use thereof | PC, TFAM, PCK2 | MLYCD 120/4885PLA2G1B 3679/4885ATG4B 3344/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.