Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | STAT3 | P40763 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | TRPV1 | Q8NER1 | 3/20 | 0.45 |
| ▸ | ADORA3 | P0DMS8 | 5/20 | 0.43 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.43 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.43 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.41 |
| ▸ | DEGS1 | O15121 | 1/20 | 0.41 |
| ▸ | KCNQ3 | O43525 | 1/20 | 0.40 |
| ▸ | KCNQ2 | O43526 | 1/20 | 0.40 |
| ▸ | KCNE1 | P15382 | 1/20 | 0.40 |
| ▸ | KCNQ1 | P51787 | 1/20 | 0.40 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.40 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18230296 | 0.87 | TRPV1 (0.54) | ALDH1A1LMNAMAPTHTTSMN1; SMN2 | |
| SCHEMBL18230475 | 0.85 | MAPT (0.45) | STAT3ALDH1A1LMNAMAPTHTT | |
| SCHEMBL18113950 | 0.83 | ADORA3 (0.39) | ALDH1A1TRPV1ADORA3ADORA2A | |
| SCHEMBL18230441 | 0.83 | LMNA (0.43) | STAT3ALDH1A1LMNAMAPTHTT | |
| SCHEMBL18230504 | 0.80 | SCD (0.47) | ALDH1A1LMNAMAPTHTTSMN1; SMN2 | |
| SCHEMBL18230321 | 0.79 | ADORA2A (0.48) | ALDH1A1LMNAMAPTHTTSMN1; SMN2 | |
| SCHEMBL18230513 | 0.79 | TLR7 (0.49) | LMNAMAPTTRPV1ADORA2AKCNQ3 | |
| SCHEMBL18230430 | 0.78 | LMNA (0.40) | STAT3ALDH1A1LMNAMAPTHTT | |
| SCHEMBL18230362 | 0.77 | LRRK2 (0.45) | ALDH1A1LMNAMAPTHTTSMN1; SMN2 | |
| SCHEMBL18230481 | 0.77 | STAT3 (0.47) | STAT3LMNAMAPTHTTSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2016183173-A1 | ANTIPARASITIC COMPOUNDS | Avista Pharma Solutions (US) | 2016-11-17 | — | — | WO | disclosed |
| WO-2016183173-A1 | ANTIPARASITIC COMPOUNDS | Avista Pharma Solutions (US) | 2016-11-17 | — | — | WO | disclosed |