SCHEMBL18249869

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL20239299	0.81	LOXL2 (0.57)	LOXL2LOX
	SCHEMBL18249748	0.81	P2RX3 (0.47)	LOXL2SMN1; SMN2LMNAACACBFFAR1
	SCHEMBL20239198	0.74	DGAT2 (0.37)	ALDH1A1LOXL2SMN1; SMN2LMNAHPGD
	SCHEMBL20239324	0.74	VNN1 (0.41)	LOXL2LOX
	SCHEMBL18249856	0.74	LOXL2 (0.39)	LOXL2LOXACACBMETFFAR1
	SCHEMBL2892270	0.72	LOXL2 (0.53)	KDM4EALDH1A1L3MBTL1LOXL2SMN1; SMN2
	SCHEMBL20239285	0.72	VNN1 (0.38)	ALDH1A1LOXL2LMNAMET
	SCHEMBL20239161	0.72	DGAT2 (0.36)	LOXL2LOXACACBMET
	SCHEMBL20239160	0.72	PGR (0.37)	KDM4EALDH1A1LOXL2SMN1; SMN2LMNA
	SCHEMBL18249754	0.72	KDR (0.41)	KDM4EALDH1A1SMN1; SMN2LMNAHPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.