Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DNM2 | P50570 | 8/20 | 0.46 |
| ▸ | LMNA | P02545 | 4/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.44 |
| ▸ | HTT | P42858 | 3/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.40 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 4/20 | 0.38 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.38 |
| ▸ | ESR1 | P03372 | 1/20 | 0.37 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.37 |
| ▸ | USP2 | O75604 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16608746 | 0.82 | LMNA (0.50) | DNM2LMNASMN1; SMN2HTTMAPK1 | |
| SCHEMBL16608745 | 0.75 | DNM2 (0.61) | DNM2LMNASMN1; SMN2HTTMAPK1 | |
| SCHEMBL16608857 | 0.72 | ALDH1A1 (0.73) | DNM2LMNASMN1; SMN2HTTMAPK1 | |
| SCHEMBL25166554 | 0.72 | NOS3 (0.48) | DNM2LMNASMN1; SMN2HTTMAPK1 | |
| SCHEMBL1194281 | 0.71 | DNM2 (0.78) | DNM2LMNASMN1; SMN2HTTMAPK1 | |
| SCHEMBL8349354 | 0.70 | KMT2A (0.58) | LMNAMAPK1KMT2AMEN1GAA | |
| SCHEMBL13329946 | 0.70 | DNM2 (0.81) | DNM2LMNASMN1; SMN2HTTMAPK1 | |
| SCHEMBL13329945 | 0.70 | DNM2 (0.81) | DNM2LMNASMN1; SMN2HTTMAPK1 | |
| SCHEMBL12230238 | 0.69 | MAPT (0.45) | DNM2LMNASMN1; SMN2HTTMAPK1 | |
| SCHEMBL15786324 | 0.68 | DNM2 (0.50) | DNM2LMNASMN1; SMN2HTTMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20160357945-A1 | METHODS AND SYSTEMS FOR ORGANIC SOLUTE SAMPLING OF AQUEOUS AND HETEROGENEOUS ENVIRONMENTS | UNIVERSITY OF MARYLAND, BALTIMORE (US) | 2016-12-08 | — | — | US | disclosed |