Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | USP7 | Q93009 | 1/20 | 0.34 |
| ▸ | RPS6KA3 | P51812 | 1/20 | 0.34 |
| ▸ | KDM1A | O60341 | 2/20 | 0.34 |
| ▸ | ALOX5AP | P20292 | 4/20 | 0.33 |
| ▸ | FEN1 | P39748 | 4/20 | 0.33 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.33 |
| ▸ | PTGS2 | P35354 | 3/20 | 0.33 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.33 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.31 |
| ▸ | TGFBR1 | P36897 | 1/20 | 0.31 |
| ▸ | KIT | P10721 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
| ▸ | USP2 | O75604 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.30 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.30 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.30 |
| ▸ | KLK7 | P49862 | 1/20 | 0.30 |
| ▸ | PIM1 | P11309 | 1/20 | 0.30 |
| ▸ | SRC | P12931 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18306348 | 0.92 | RPS6KA3 (0.37) | RPS6KA3ALOX5APFEN1CYP2A6PTGS2 | |
| SCHEMBL18306366 | 0.86 | FYN (0.36) | PTGS2PTGS1 | |
| SCHEMBL18306342 | 0.85 | KMT2A (0.40) | ALOX5APFEN1KMT2A | |
| SCHEMBL18306341 | 0.84 | ADORA1 (0.42) | KDM1ACYP2A6PTGS2PTGS1TGFBR1 | |
| SCHEMBL18306449 | 0.83 | KDM1A (0.43) | USP7KDM1AKMT2AALDH1A1HSD17B10 | |
| SCHEMBL18306344 | 0.82 | MAP4K4 (0.37) | RPS6KA3ALOX5APFEN1PTGS2PTGS1 | |
| SCHEMBL18306367 | 0.82 | AURKA (0.37) | RPS6KA3ALOX5APFEN1PTGS2PTGS1 | |
| SCHEMBL18306345 | 0.81 | PTGS2 (0.39) | RPS6KA3ALOX5APFEN1PTGS2PTGS1 | |
| SCHEMBL18306343 | 0.81 | ABL1 (0.36) | ALOX5APFEN1CYP2A6KMT2ASRC | |
| SCHEMBL18306440 | 0.79 | AURKA (0.34) | RPS6KA3KDM1AALOX5APFEN1PTGS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170342048-A1 | GDF-8 Inhibitors | MIDCAP FINANCIAL TRUST | 2017-11-30 | — | — | US | disclosed |
| US-9518040-B2 | GDF-8 inhibitors | RIGEL PHARMACEUTICALS, INC. (US) | 2016-12-13 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170342048-A1 | GDF-8 Inhibitors | MSTN, MYOF, CXCL8 | USP7 3465/4885RPS6KA3 1056/4885KDM1A 3237/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.