Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.35 |
| ▸ | CA2 | P00918 | 3/20 | 0.35 |
| ▸ | CCNE1 | P24864 | 1/20 | 0.34 |
| ▸ | CDK2 | P24941 | 1/20 | 0.34 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.34 |
| ▸ | CDK5R1 | Q15078 | 1/20 | 0.34 |
| ▸ | RORC | P51449 | 4/20 | 0.32 |
| ▸ | CA1 | P00915 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 4/20 | 0.31 |
| ▸ | MAPT | P10636 | 4/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.31 |
| ▸ | GLA | P06280 | 3/20 | 0.31 |
| ▸ | GAA | P10253 | 3/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.30 |
| ▸ | NPC1 | O15118 | 2/20 | 0.30 |
| ▸ | APP | P05067 | 2/20 | 0.30 |
| ▸ | RAB9A | P51151 | 2/20 | 0.30 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12652647 | 0.89 | GPR35 (0.37) | GPR35CA2CA1 | |
| SCHEMBL14000916 | 0.77 | RAB9A (0.38) | MAPTGLAGAAKMT2ANPC1 | |
| SCHEMBL14000717 | 0.76 | PTPN1 (0.41) | GPR35CA2CCNE1CDK2CDK5 | |
| SCHEMBL183510 | 0.76 | CA2 (0.41) | CA2CCNE1CDK2CDK5CDK5R1 | |
| SCHEMBL13953030 | 0.74 | GPR35 (0.46) | GPR35CA2HPGDMAPTALDH1A1 | |
| SCHEMBL15080286 | 0.73 | GPR35 (0.56) | GPR35CA2CCNE1CDK2CDK5 | |
| SCHEMBL17856924 | 0.72 | PTPN1 (0.38) | GPR35CA2CCNE1CDK2CDK5 | |
| SCHEMBL138997 | 0.72 | PTPN1 (0.38) | GPR35CA2CCNE1CDK2CDK5 | |
| SCHEMBL17856889 | 0.72 | GPR35 (0.43) | GPR35CA2RORCHPGDMAPT | |
| SCHEMBL140675 | 0.72 | GPR35 (0.52) | GPR35CA2CCNE1CDK2CDK5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120058501-A1 | OXIDIZED GLUTATHIONE ASSAY | JPMORGAN CHASE BANK, N.A., AS COLLATERAL AGENT | 2012-03-08 | — | — | US | disclosed |