Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | CA2 | P00918 | 3/20 | 0.35 |
| ▸ | NPY1R | P25929 | 3/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | EPHX2 | P34913 | 3/20 | 0.35 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.35 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.35 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.34 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.34 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.34 |
| ▸ | AURKA | O14965 | 1/20 | 0.34 |
| ▸ | CHUK | O15111 | 1/20 | 0.34 |
| ▸ | DAPK3 | O43293 | 1/20 | 0.34 |
| ▸ | JAK2 | O60674 | 1/20 | 0.34 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.34 |
| ▸ | PAK4 | O96013 | 1/20 | 0.34 |
| ▸ | CHEK2 | O96017 | 1/20 | 0.34 |
| ▸ | PRKCG | P05129 | 1/20 | 0.34 |
| ▸ | CDK1 | P06493 | 1/20 | 0.34 |
| ▸ | MET | P08581 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Trifluoroacetic Acid SCHEMBL18863732 | 0.83 | ACHE (0.43) | SMN1; SMN2CA2NPY1R | |
| SCHEMBL18334634 | 0.79 | SMN1; SMN2 (0.42) | SMN1; SMN2CA2EPHX2MEN1KMT2A | |
| SCHEMBL17039661 | 0.77 | SMN1; SMN2 (0.58) | SMN1; SMN2LMNA | |
| Trifluoroacetic Acid SCHEMBL5903474 | 0.76 | SMN1; SMN2 (0.44) | SMN1; SMN2RAB9ALMNAMAPT | |
| SCHEMBL22844929 | 0.74 | SMN1; SMN2 (0.46) | SMN1; SMN2CA2HDAC3HDAC1MEN1 | |
| SCHEMBL22844978 | 0.73 | SMN1; SMN2 (0.44) | SMN1; SMN2CA2RAB9AHDAC3HDAC1 | |
| SCHEMBL22844962 | 0.73 | SMN1; SMN2 (0.44) | SMN1; SMN2CA2RAB9AHDAC3HDAC1 | |
| SCHEMBL17039696 | 0.73 | SMN1; SMN2 (0.48) | SMN1; SMN2CA2HDAC3HDAC1KMT2A | |
| SCHEMBL19173002 | 0.73 | RAB9A (0.50) | SMN1; SMN2CA2RAB9AMEN1LMNA | |
| SCHEMBL16619189 | 0.72 | SMN1; SMN2 (0.57) | SMN1; SMN2RAB9AEPHX2HDAC3HDAC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11161884-B2 | Modified biotin, streptavidin mutant, and usage of them | SAVID THERAPEUTICS INC. (JP) | 2021-11-02 | — | — | US | disclosed |
| US-11124549-B2 | — | — | 2021-09-21 | — | — | US | disclosed |
| EP-3842440-A2 | MODIFIED BIOTIN, STREPTAVIDIN MUTANT, AND USAGE OF THEM | Savid Therapeutics Inc. (JP) | 2021-06-30 | — | — | EP | disclosed |
| EP-3109252-B1 | MODIFIED BIOTIN, STREPTAVIDIN MUTANT, AND USAGE OF THEM | SAVID THERAPEUTICS INC (JP) | 2020-12-30 | — | — | EP | disclosed |
| EP-3109252-A1 | BIOTIN VARIANT, STREPTAVIDIN MUTANT, AND USES THEREOF | Savid Therapeutics Inc. (JP) | 2016-12-28 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11124549-B2 | — | BTD, HLCS, BROX | SMN1; SMN2 4219/4885CA2 4845/4885NPY1R 1255/4885 |
| US-11161884-B2 | Modified biotin, streptavidin mutant, and usage of them | BTD, HLCS, BROX | SMN1; SMN2 4362/4885CA2 4860/4885NPY1R 2314/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.