Trifluoroacetic Acid

Trifluoroacetic Acid

SCHEMBL18863732

NCCOCCNC(=O)c1cc(NC(=O)NCCOCCOCCN(Cc2ccccc2)C(=O)O)cc(C(=O)NCCOCCN)c1.O=C(O)C(F)(F)F.O=C(O)C(F)(F)F

nearest known ligand 0.43

Full drug profile on Sugi Atlas →

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
▸ ACHE P22303 11/20 0.43
▸ SMN1; SMN2 Q16637 1/20 0.40
▸ NPY1R P25929 2/20 0.37
▸ TACR2 P21452 1/20 0.36
▸ CA2 P00918 1/20 0.36
▸ TMEM97 Q5BJF2 1/20 0.36
▸ SIGMAR1 Q99720 1/20 0.36
▸ HTR5A P47898 2/20 0.35
▸ MLYCD O95822 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18863746 0.83 ACHE (0.45) ACHESMN1; SMN2TMEM97SIGMAR1
Trifluoroacetic Acid SCHEMBL18334635 0.83 SMN1; SMN2 (0.41) SMN1; SMN2NPY1RCA2
SCHEMBL17039661 0.78 SMN1; SMN2 (0.58) SMN1; SMN2
Trifluoroacetic Acid SCHEMBL18863735 0.76 FOLH1 (0.50) CA2
SCHEMBL2582068 0.74 ALDH1A1 (0.44) SMN1; SMN2
Trifluoroacetic Acid SCHEMBL30337983 0.70 SMN1; SMN2 (0.60) SMN1; SMN2CA2MLYCD
SCHEMBL17039700 0.69 SMN1; SMN2 (0.55) SMN1; SMN2
SCHEMBL10064731 0.68 SMN1; SMN2 (0.84) SMN1; SMN2CA2
SCHEMBL28984149 0.68 SMN1; SMN2 (0.84) SMN1; SMN2CA2
SCHEMBL28510822 0.68 CHEK1 (0.37) SMN1; SMN2CA2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11286285-B2 Modified biotin, streptavidin mutant, and usage of them SAVID THERAPEUTICS INC. (JP) 2022-03-29 — — US disclosed
US-20170145063-A1 MODIFIED BIOTIN, STREPTAVIDIN MUTANT, AND USAGE OF THEM SAVID THERAPEUTICS INC. (JP) 2017-05-25 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20170145063-A1 MODIFIED BIOTIN, STREPTAVIDIN MUTANT, AND USAGE OF THEM BTD, HLCS, BROX ACHE 4415/4885SMN1; SMN2 4476/4885NPY1R 3182/4885
US-11286285-B2 Modified biotin, streptavidin mutant, and usage of them BTD, HLCS, BROX ACHE 4415/4885SMN1; SMN2 4476/4885NPY1R 3182/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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