Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLA2G7 | Q13093 | 1/20 | 0.37 |
| ▸ | PARP1 | P09874 | 1/20 | 0.37 |
| ▸ | SKP2 | Q13309 | 1/20 | 0.36 |
| ▸ | LPL | P06858 | 1/20 | 0.36 |
| ▸ | LIPG | Q9Y5X9 | 1/20 | 0.36 |
| ▸ | PPARG | P37231 | 2/20 | 0.35 |
| ▸ | PPARA | Q07869 | 2/20 | 0.35 |
| ▸ | DHFR | P00374 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30947424 | 1.00 | PLA2G7 (0.37) | PLA2G7PARP1SKP2LPLLIPG | |
| SCHEMBL18347219 | 0.88 | PLA2G7 (0.40) | PLA2G7LPLLIPGPPARGPPARA | |
| SCHEMBL18347244 | 0.85 | ADORA2A (0.37) | — | |
| SCHEMBL18347218 | 0.83 | POLB (0.45) | PLA2G7 | |
| SCHEMBL18347229 | 0.82 | PLK1 (0.38) | PLA2G7 | |
| SCHEMBL2175874 | 0.81 | TSHR (0.44) | DHFR | |
| SCHEMBL18347213 | 0.80 | THRB (0.45) | PLA2G7 | |
| SCHEMBL18347221 | 0.80 | KCNA3 (0.47) | PLA2G7 | |
| SCHEMBL2176981 | 0.80 | SMN1; SMN2 (0.34) | PLA2G7PARP1 | |
| SCHEMBL2177161 | 0.78 | XDH (0.34) | PLA2G7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20160376235-A1 | Pyridone FabI Inhibitors and Uses Thereof | THE RESEARCH FOUNDATION FOR THE STATE UNIVERSITY OF NEW YORK | 2016-12-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160376235-A1 | Pyridone FabI Inhibitors and Uses Thereof | PLPBP, PDXK, FBP1 | PLA2G7 672/4885PARP1 1850/4885SKP2 2838/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.