SCHEMBL18347221

SCHEMBL18347221

CCCCCCc1ccn(Cc2ccccc2Cl)c(=O)c1

nearest known ligand 0.72

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
▸ KCNA3 P22001 1/20 0.47
▸ CNR1 P21554 2/20 0.43
▸ CNR2 P34972 2/20 0.43
▸ GPR55 Q9Y2T6 1/20 0.41
▸ KDM4E B2RXH2 1/20 0.41
▸ ALDH1A1 P00352 1/20 0.41
▸ PLA2G7 Q13093 1/20 0.41
▸ SMN1; SMN2 Q16637 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27568558 0.92 KCNA3 (0.41) KCNA3CNR1CNR2GPR55KDM4E
SCHEMBL18347218 0.86 POLB (0.45) CNR1CNR2GPR55KDM4EALDH1A1
SCHEMBL18347228 0.85 MAPK14 (0.49) KCNA3PLA2G7
SCHEMBL18347213 0.85 THRB (0.45) KDM4EALDH1A1PLA2G7
SCHEMBL18347251 0.84 PTGER3 (0.51) KDM4EALDH1A1SMN1; SMN2
SCHEMBL18347209 0.82 TSHR (0.40) ALDH1A1PLA2G7SMN1; SMN2
SCHEMBL18347225 0.82 KCNA3 (0.47) KCNA3
SCHEMBL18347219 0.81 PLA2G7 (0.40) CNR1CNR2GPR55PLA2G7
SCHEMBL29565027 0.81 TSHR (0.41) ALDH1A1PLA2G7SMN1; SMN2
SCHEMBL18347226 0.80 PLA2G7 (0.37) PLA2G7

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 23 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240251654-A1 ORGANIC ELECTROLUMINESCENT DEVICE Beijing Summer Sprout Technology Co., Ltd. (CN) 2024-07-25 — — US claimed
US-20260029401-A1 METHODS AND SYSTEMS FOR CHARACTERIZING PROTEOFORMS OF SIGNIFICANT PROTEINS OF INTEREST NAUTILUS SUBSIDIARY INC (US) 2026-01-29 — — US disclosed
US-12370164-B2 Chlorogenic acid composition for promoting a healthy body weight Vidya Herbs, Inc. (US) 2025-07-29 — — US disclosed
US-20250206708-A1 AN OXAZIRIDINE PLATFORM FOR TARGETING FUNCTIONAL ALLOSTERIC METHIONINE SITES NOVARTIS AG (CH) 2025-06-26 — — US disclosed
EP-4499617-A1 AN OXAZIRIDINE PLATFORM FOR TARGETING FUNCTIONAL ALLOSTERIC METHIONINE SITES Novartis AG (CH) 2025-02-05 — — EP disclosed
US-20250011734-A1 DGAT1/2-INDEPENDENT ENZYME SYNTHESIZING STORAGE LIPIDS (DIESL) Stichting Het Nederlands Kanker Instituut-Antoni van Leeuwenhoek Ziekenhuis (NL) 2025-01-09 — — US disclosed
WO-2024262280-A1 ANTI-GAP 43 ANTIBODY, METHOD FOR PRODUCING SAME, AND TISSUE ANALYSIS METHOD AND KIT FOR TISSUE ANALYSIS METHOD USING SAME 国立大学法人新潟大学 2024-12-26 — — WO disclosed
US-20240426824-A1 METHODS RELATING TO TREATMENT OF ACUTE MYELOID LEUKEMIA BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM 2024-12-26 — — US disclosed
US-20240321457-A1 SYSTEMS FOR AND METHODS OF TREATMENT SELECTION THE REGENTS OF THE UNIVERSITY OF CALIFORNIA 2024-09-26 — — US disclosed
EP-4430173-A1 DGAT1/2-INDEPENDENT ENZYME SYNTHESIZING STORAGE LIPIDS (DIESL) Stichting Het Nederlands Kanker Instituut- Antoni van Leeuwenhoek Ziekenhuis (NL) 2024-09-18 — — EP disclosed
WO-2023192328-A1 AN OXAZIRIDINE PLATFORM FOR TARGETING FUNCTIONAL ALLOSTERIC METHIONINE SITES NOVARTIS AG (CH) 2023-10-05 — — WO disclosed
CN-116779604-A Integrated circuit 三星电子株式会社 2023-09-19 — — CN disclosed
US-11752124-B2 Chlorogenic acid composition for supporting healthy lipid levels Vidya Herbs, Inc. (US) 2023-09-12 — — US disclosed
CN-109087914-B Integrated circuit and computer-implemented method of generating a layout for an integrated circuit 三星电子株式会社 2023-06-23 — — CN disclosed
WO-2023085926-A1 DGAT1/2-INDEPENDENT ENZYME SYNTHESIZING STORAGE LIPIDS (DIESL) Stichting Het Nederlands Kanker Instituut-Antoni van Leeuwenhoek Ziekenhuis (NL) 2023-05-19 — — WO disclosed
US-11572341-B2 Biguanide compound and use thereof IMMUNOMET THERAPEUTICS INC. (US) 2023-02-07 — — US disclosed
WO-2022221553-A1 AMARANTHUS EXTRACTS FOR USE IN TREATING OBESITY BIONEXUS LLC (US) 2022-10-20 — — WO disclosed
US-20220195533-A1 ARYL HYDROCARBON RECEPTOR (AHR) ACTIVATION SIGNATURE AND METHODS FOR DETERMINING AHR SIGNALING STATUS DEUTSCHES KREBSFORSCHUNGSZENTRUM STIFTUNG DES OFFENTLICHEN RECHTS (DE) 2022-06-23 — — US disclosed
WO-2022081923-A2 SYSTEMS FOR AND METHODS OF TREATMENT SELECTION THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2022-04-21 — — WO disclosed
US-20160376235-A1 Pyridone FabI Inhibitors and Uses Thereof THE RESEARCH FOUNDATION FOR THE STATE UNIVERSITY OF NEW YORK 2016-12-29 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20160376235-A1 Pyridone FabI Inhibitors and Uses Thereof PLPBP, PDXK, FBP1 KCNA3 3748/4885CNR1 2546/4885CNR2 3040/4885
US-20260029401-A1 METHODS AND SYSTEMS FOR CHARACTERIZING PROTEOFORMS OF SIGNIFICANT PROTEINS OF INTEREST AKT1, LRRK2, AKT2 KCNA3 4571/4885CNR1 3382/4885CNR2 2838/4885
US-20250206708-A1 AN OXAZIRIDINE PLATFORM FOR TARGETING FUNCTIONAL ALLOSTERIC METHIONINE SITES MARCKS, PTMS, DMPK KCNA3 3631/4885CNR1 4298/4885CNR2 4441/4885
US-11572341-B2 Biguanide compound and use thereof MKI67, GCG, GCKR KCNA3 2570/4885CNR1 2826/4885CNR2 3041/4885
US-20240251654-A1 ORGANIC ELECTROLUMINESCENT DEVICE LEF1, EFNA1, EML4 KCNA3 563/4885CNR1 3626/4885CNR2 4346/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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