Sugi Predict

Sugi Predict / Compounds / SCHEMBL1836068

SCHEMBL1836068

SCHEMBL1836068

CCn1c(C)cc(C)[n+](CC)c1=O

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ POLB P06746 1/20 0.43
▸ KDM4E B2RXH2 7/20 0.40
▸ LMNA P02545 1/20 0.40
▸ ALDH1A1 P00352 4/20 0.33
▸ MEN1 O00255 3/20 0.33
▸ MAPT P10636 3/20 0.33
▸ KMT2A Q03164 3/20 0.33
▸ NPC1 O15118 2/20 0.33
▸ RAB9A P51151 2/20 0.33
▸ SMN1; SMN2 Q16637 2/20 0.33
▸ APOBEC3A P31941 1/20 0.33
▸ APOBEC3G Q9HC16 1/20 0.33
▸ SRC P12931 1/20 0.33
▸ HTT P42858 2/20 0.32
▸ CTDSP1 Q9GZU7 1/20 0.32
▸ NSD2 O96028 1/20 0.32
▸ NPSR1 Q6W5P4 1/20 0.32
▸ HSD17B10 Q99714 1/20 0.32
▸ RXFP1 Q9HBX9 1/20 0.32
▸ TDP1 Q9NUW8 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2519291 0.73 KDM4E (0.41) POLBKDM4ELMNAALDH1A1MEN1
Hydrochloric Acid SCHEMBL3396465 0.72 KDM4E (0.41) POLBKDM4ELMNAALDH1A1MEN1
SCHEMBL30352664 0.68 POLB (0.54) POLBKDM4ELMNAALDH1A1MEN1
Hydrochloric Acid SCHEMBL5711289 0.67 HSD17B10 (0.44) POLBKDM4ELMNAALDH1A1MEN1
SCHEMBL4768929 0.67 POLB (0.59) POLBKDM4ELMNAALDH1A1MEN1
Sulfuric Acid SCHEMBL3401378 0.65 KDM4E (0.35) POLBKDM4ELMNAALDH1A1MEN1
SCHEMBL11837808 0.63 POLB (0.64) POLBKDM4ELMNAALDH1A1MEN1
Bromide SCHEMBL29129739 0.60 MAPT (0.39) KDM4ELMNAALDH1A1MAPTRAB9A
Iodide SCHEMBL31265537 0.60 MAPT (0.44) POLBKDM4ELMNAALDH1A1MEN1
Hydrochloric Acid SCHEMBL31265533 0.60 MAPT (0.39) POLBKDM4ELMNAALDH1A1MEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 71 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2358343-B1 METHOD FOR DECOLOURING KERATINOUS FIBRES HENKEL AG & CO KGAA (DE) 2016-10-19 — — EP claimed
EP-1965753-B1 REVERSIBLY CHANGEABLE HAIR COLOR HENKEL AG & CO KGAA (DE) 2013-09-04 — — EP claimed
US-8268015-B2 Method for decolorizing keratin-containing fibers HENKEL AG & CO. KGAA (DE) 2012-09-18 — — US claimed
US-20110247644-A1 Method for Decolorizing Keratin-Containing Fibers HENKEL AG & CO. KGAA (DE) 2011-10-13 — — US claimed
US-7799096-B2 Agent for dyeing keratin-containing fibers HENKEL AG & CO. KGAA (DE) 2010-09-21 — — US claimed
US-20100064450-A1 AGENT FOR DYEING KERATIN-CONTAINING FIBERS HENKEL AG & CO. KGAA (DE) 2010-03-18 — — US claimed
US-20100037909-A1 SUBSTANCES FOR DYEING KERATINOUS FIBERS HENKEL AG & CO. KGAA (DE) 2010-02-18 — — US claimed
EP-2014275-A2 Kit for preparing storage-stable formulations Henkel AG & Co. KGaA (DE) 2009-01-14 — — EP claimed
US-20080301885-A1 REVERSIBLY CHANGEABLE HAIR COLOR HENKEL AG & CO. KGAA (DE) 2008-12-11 — — US claimed
US-7393367-B2 Agent for dyeing keratin-based fibers HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (DE) 2008-07-01 — — US claimed
US-20080104772-A1 AGENT FOR DYEING KERATIN-BASED FIBERS HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (DE) 2008-05-08 — — US claimed
EP-1534227-B1 AGENTS USED FOR DYEING KERATINOUS FIBERS HENKEL KGAA (DE) 2006-12-27 — — EP claimed
US-11918671-B2 Multi-tone hair dyeing method in three steps HENKEL AG & CO. KGAA (DE) 2024-03-05 — — US disclosed
US-20230031764-A1 MULTI-TONE HAIR DYEING METHOD IN THREE STEPS HENKEL AG & CO. KGAA (DE) 2023-02-02 — — US disclosed
CN-114746069-A Three-step multi-tone hair dyeing method 汉高股份有限及两合公司 2022-07-12 — — CN disclosed
EP-2044977-B1 Hair dye with oxidative pre-treatment HENKEL AG & CO KGAA (DE) 2018-02-14 — — EP disclosed
EP-1813260-A2 Bleaching and/or colouring agent with reduced potential for irritation Henkel Kommanditgesellschaft auf Aktien (DE) 2007-08-01 — — EP disclosed
EP-1813261-A2 Bleaching method for keratinic fibres Henkel Kommanditgesellschaft auf Aktien (DE) 2007-08-01 — — EP disclosed
EP-1813259-A2 Bleaching and/or colouring agent with reduced potential for irritation Henkel Kommanditgesellschaft auf Aktien (DE) 2007-08-01 — — EP disclosed
EP-1813258-A2 Bleaching and/or colouring agent with reduced potential for irritation Henkel Kommanditgesellschaft auf Aktien (DE) 2007-08-01 — — EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110247644-A1 Method for Decolorizing Keratin-Containing Fibers KRT18, PLOD3, DSG1 POLB 421/4885KDM4E 508/4885LMNA 1273/4885
US-20080104772-A1 AGENT FOR DYEING KERATIN-BASED FIBERS KRT18, KAT5, H1-5 POLB 2506/4885KDM4E 1661/4885LMNA 1743/4885
US-20100064450-A1 AGENT FOR DYEING KERATIN-CONTAINING FIBERS KRT18, CRYAA, CKAP4 POLB 1804/4885KDM4E 1842/4885LMNA 415/4885
US-20100037909-A1 SUBSTANCES FOR DYEING KERATINOUS FIBERS KRT18, H1-10, COL1A1 POLB 2891/4885KDM4E 1659/4885LMNA 1020/4885
US-11918671-B2 Multi-tone hair dyeing method in three steps TYR, HAO2, HAAO POLB 466/4885KDM4E 1526/4885LMNA 2896/4885
US-20230031764-A1 MULTI-TONE HAIR DYEING METHOD IN THREE STEPS TYR, HAO2, HAAO POLB 466/4885KDM4E 1526/4885LMNA 2896/4885
US-20080301885-A1 REVERSIBLY CHANGEABLE HAIR COLOR TYR, CBR3, COXFA4L2 POLB 1507/4885KDM4E 707/4885LMNA 913/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.