SCHEMBL18394672

SCHEMBL18394672

COC(=O)c1cc(C2CC2)sc1N1CCOCC1

nearest known ligand 0.45

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ ALDH1A1 P00352 3/20 0.43
▸ PRKDC P78527 2/20 0.41
▸ KDM4E B2RXH2 1/20 0.41
▸ GLA P06280 1/20 0.41
▸ KMT2A Q03164 4/20 0.41
▸ MEN1 O00255 3/20 0.41
▸ GAA P10253 2/20 0.41
▸ ALOX15 P16050 2/20 0.41
▸ MAPT P10636 1/20 0.41
▸ OPRK1 P41145 1/20 0.40
▸ APAF1 O14727 1/20 0.40
▸ NPC1 O15118 1/20 0.40
▸ TDP2 O95551 1/20 0.40
▸ NSD2 O96028 1/20 0.40
▸ PLA2G1B P04054 1/20 0.40
▸ HSP90AA1 P07900 1/20 0.40
▸ PLCG1 P19174 1/20 0.40
▸ RAB9A P51151 1/20 0.40
▸ GALK1 P51570 1/20 0.40
▸ BLM P54132 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18412859 0.85 PRKDC (0.46) ALDH1A1PRKDCKDM4EKMT2AMEN1
SCHEMBL20098347 0.81 ALDH1A1 (0.45) ALDH1A1PRKDCKDM4EGLAKMT2A
SCHEMBL18412862 0.80 PRKDC (0.44) ALDH1A1PRKDCKMT2AMEN1GAA
SCHEMBL18395227 0.79 KDM4E (0.45) ALDH1A1PRKDCKDM4EGLAKMT2A
SCHEMBL10288078 0.74 ALDH1A1 (0.51) ALDH1A1KDM4EKMT2AMEN1ALOX15
SCHEMBL18395143 0.73 ALDH1A1 (0.47) ALDH1A1KDM4EKMT2AMEN1GAA
SCHEMBL18395504 0.72 ALDH1A1 (0.49) ALDH1A1PRKDCKDM4EGLAKMT2A
SCHEMBL16056185 0.72 MAPT (0.44) ALDH1A1PRKDCKDM4EKMT2AMEN1
SCHEMBL2775462 0.71 ALDH1A1 (0.51) ALDH1A1KDM4EGLAKMT2AMEN1
SCHEMBL20098548 0.70 OPRK1 (0.52) ALDH1A1KDM4EKMT2AMEN1OPRK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 31 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12297209-B2 Benzodiazepine derivatives as RSV inhibitors ENANTA PHARMACEUTICALS, INC. (US) 2025-05-13 — — US disclosed
US-12268694-B2 Combination pharmaceutical agents as RSV inhibitors ENANTA PHARMACEUTICALS, INC. (US) 2025-04-08 — — US disclosed
US-20240360155-A1 Benzodiazepine Derivatives as RSV Inhibitors ENANTA PHARM INC (US) 2024-10-31 — — US disclosed
US-11952389-B2 Benzodiazepine derivatives as RSV inhibitors ENANTA PHARMACEUTICALS, INC. (US) 2024-04-09 — — US disclosed
EP-3687543-B1 COMBINATIONS OF PHARMACEUTICAL AGENTS AS RSV INHIBITORS ENANTA PHARM INC (US) 2024-03-20 — — EP disclosed
US-20230087410-A1 BENZODIAZEPINE DERIVATIVES AS RSV INHIBITORS ENANTA PHARM INC (US) 2023-03-23 — — US disclosed
US-20220323460-A1 COMBINATION PHARMACEUTICAL AGENTS AS RSV INHIBITORS ENANTA PHARM INC (US) 2022-10-13 — — US disclosed
US-11390631-B1 Benzodiazepine derivatives as RSV inhibitors ENANTA PHARMACEUTICALS, INC. (US) 2022-07-19 — — US disclosed
EP-3324977-B1 BENZODIAZEPINE DERIVATIVES AS RSV INHIBITORS ENANTA PHARM INC (US) 2022-07-13 — — EP disclosed
EP-3324977-B1 BENZODIAZEPINE DERIVATIVES AS RSV INHIBITORS ENANTA PHARM INC (US) 2022-07-13 — — EP disclosed
US-20190192535-A1 COMBINATION PHARMACEUTICAL AGENTS AS RSV INHIBITORS ENANTA PHARMACEUTICALS, INC. 2019-06-27 — — US disclosed
US-20190192535-A1 COMBINATION PHARMACEUTICAL AGENTS AS RSV INHIBITORS ENANTA PHARMACEUTICALS, INC. 2019-06-27 — — US disclosed
WO-2019067864-A1 COMBINATION PHARMACEUTICAL AGENTS AS RSV INHIBITORS ENANTA PHARMACEUTICALS, INC. (US) 2019-04-04 — — WO disclosed
WO-2019067864-A1 COMBINATION PHARMACEUTICAL AGENTS AS RSV INHIBITORS ENANTA PHARMACEUTICALS, INC. (US) 2019-04-04 — — WO disclosed
US-20180258102-A1 BENZODIAZEPINE DERIVATIVES AS RSV INHIBITORS ENANTA PHARM INC (US) 2018-09-13 — — US disclosed
EP-3324977-A1 BENZODIAZEPINE DERIVATIVES AS RSV INHIBITORS Enanta Pharmaceuticals, Inc. (US) 2018-05-30 — — EP disclosed
US-9957281-B2 Benzodiazepine derivatives as RSV inhibitors ENANTA PHARMACEUTICALS, INC. (US) 2018-05-01 — — US disclosed
US-9957281-B2 Benzodiazepine derivatives as RSV inhibitors ENANTA PHARMACEUTICALS, INC. (US) 2018-05-01 — — US disclosed
US-20170022221-A1 BENZODIAZEPINE DERIVATIVES AS RSV INHIBITORS ENANTA PHARMACEUTICALS, INC. 2017-01-26 — — US disclosed
WO-2017015449-A1 BENZODIAZEPINE DERIVATIVES AS RSV INHIBITORS ENANTA PHARMACEUTICALS, INC. (US) 2017-01-26 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (10 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240360155-A1 Benzodiazepine Derivatives as RSV Inhibitors GABRA5, GABRA1, GABBR2 ALDH1A1 621/4885PRKDC 4871/4885KDM4E 1198/4885
US-11952389-B2 Benzodiazepine derivatives as RSV inhibitors GABRA5, GABRA1, GABBR2 ALDH1A1 621/4885PRKDC 4871/4885KDM4E 1198/4885
US-11390631-B1 Benzodiazepine derivatives as RSV inhibitors GABRA5, GABRA1, GABBR2 ALDH1A1 621/4885PRKDC 4871/4885KDM4E 1198/4885
US-12297209-B2 Benzodiazepine derivatives as RSV inhibitors GABRA5, GABRA1, GABBR2 ALDH1A1 621/4885PRKDC 4871/4885KDM4E 1198/4885
US-20220323460-A1 COMBINATION PHARMACEUTICAL AGENTS AS RSV INHIBITORS SERPINB1, FURIN, HIF1AN ALDH1A1 3562/4885PRKDC 4881/4885KDM4E 3876/4885
US-20230087410-A1 BENZODIAZEPINE DERIVATIVES AS RSV INHIBITORS GABRA5, GABRA1, GABBR2 ALDH1A1 621/4885PRKDC 4871/4885KDM4E 1198/4885
US-12268694-B2 Combination pharmaceutical agents as RSV inhibitors ACE, ACE2, SPCS3 ALDH1A1 4172/4885PRKDC 4872/4885KDM4E 4059/4885
US-20170022221-A1 BENZODIAZEPINE DERIVATIVES AS RSV INHIBITORS GABRA5, GABRA1, GABBR2 ALDH1A1 621/4885PRKDC 4871/4885KDM4E 1198/4885
US-20180258102-A1 BENZODIAZEPINE DERIVATIVES AS RSV INHIBITORS GABRA5, GABRA1, GABBR2 ALDH1A1 621/4885PRKDC 4871/4885KDM4E 1198/4885
US-20190192535-A1 COMBINATION PHARMACEUTICAL AGENTS AS RSV INHIBITORS SERPINB1, FURIN, HIF1AN ALDH1A1 3562/4885PRKDC 4881/4885KDM4E 3876/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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