Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.39 |
| ▸ | LMNA | P02545 | 3/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | DRD2 | P14416 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.37 |
| ▸ | MEN1 | O00255 | 3/20 | 0.37 |
| ▸ | PKM | P14618 | 1/20 | 0.37 |
| ▸ | KDM5C | P41229 | 1/20 | 0.37 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27238068 | 0.83 | KDM5C (0.45) | ALDH1A1LMNAMAPTKDM4EDRD2 | |
| SCHEMBL17155190 | 0.82 | KDM5C (0.40) | ALDH1A1KDM4EKMT2AMEN1KDM5C | |
| SCHEMBL17152939 | 0.80 | ALDH1A1 (0.59) | ALDH1A1LMNAMAPTKDM4EKMT2A | |
| SCHEMBL12195291 | 0.79 | KDM4E (0.56) | ALDH1A1LMNAMAPTKDM4EL3MBTL1 | |
| SCHEMBL16656263 | 0.79 | KDM4E (0.56) | ALDH1A1LMNAMAPTKDM4EL3MBTL1 | |
| SCHEMBL7469985 | 0.79 | ALDH1A1 (0.43) | ALDH1A1LMNAMAPTKMT2AMEN1 | |
| SCHEMBL17152949 | 0.78 | CTSB (0.44) | ALDH1A1LMNAMAPTKDM4EDRD2 | |
| SCHEMBL17986173 | 0.78 | KDM4E (0.55) | ALDH1A1LMNAMAPTKDM4EKMT2A | |
| SCHEMBL5783473 | 0.78 | ENPP2 (0.51) | ALDH1A1LMNAMAPTDRD2POLB | |
| SCHEMBL9883952 | 0.77 | ALDH1A1 (0.48) | ALDH1A1LMNAMAPTKDM4EL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170022201-A1 | MACROCYLIC PYRIDINE DERIVATIVES | JANSSEN PHARMACEUTICA NV (BE) | 2017-01-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170022201-A1 | MACROCYLIC PYRIDINE DERIVATIVES | VPS26B, VPS4B, VPS28 | ALDH1A1 4381/4885LMNA 4810/4885MAPT 3312/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.