Sugi Predict

Sugi Predict / Compounds / SCHEMBL184071

SCHEMBL184071

SCHEMBL184071

CCOC(=O)C1CCN(Cc2ccccc2)CC1=O

nearest known ligand 0.58

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
▸ MEN1 O00255 1/20 0.56
▸ KMT2A Q03164 1/20 0.56
▸ ALDH1A1 P00352 4/20 0.56
▸ CCR8 P51685 1/20 0.53
▸ L3MBTL1 Q9Y468 2/20 0.51
▸ ATM Q13315 1/20 0.51
▸ KDM4E B2RXH2 4/20 0.49
▸ MAPT P10636 1/20 0.49
▸ SMN1; SMN2 Q16637 1/20 0.48
▸ SIGMAR1 Q99720 1/20 0.47
▸ BCHE P06276 1/20 0.47
▸ ACHE P22303 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL184070 0.99 MEN1 (0.55) MEN1KMT2AALDH1A1CCR8L3MBTL1
SCHEMBL5413556 0.93 L3MBTL1 (0.57) MEN1KMT2AALDH1A1CCR8L3MBTL1
SCHEMBL5752863 0.89 L3MBTL1 (0.48) MEN1KMT2AALDH1A1CCR8L3MBTL1
SCHEMBL1622710 0.89 ALDH1A1 (0.57) MEN1KMT2AALDH1A1CCR8L3MBTL1
SCHEMBL350213 0.89 FKBP1A (0.47) MEN1KMT2ASMN1; SMN2SIGMAR1BCHE
Hydrochloric Acid SCHEMBL5779638 0.89 SMN1; SMN2 (0.47) MEN1KMT2AALDH1A1CCR8L3MBTL1
Hydrochloric Acid SCHEMBL1621693 0.88 ALDH1A1 (0.56) MEN1KMT2AALDH1A1CCR8L3MBTL1
Hydrochloric Acid SCHEMBL17611756 0.88 FKBP1A (0.47) MEN1KMT2ASMN1; SMN2SIGMAR1BCHE
SCHEMBL183706 0.87 ALDH1A1 (0.52) MEN1KMT2AALDH1A1CCR8L3MBTL1
SCHEMBL350620 0.87 SIGMAR1 (0.48) SIGMAR1BCHEACHE

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 612 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114354942-A Microfluidic chip, kit and method for detecting beta-amyloid 1-42 江苏汇先医药技术有限公司 2022-04-15 — — CN claimed
US-12583871-B2 PRMT5 inhibitors MERCK SHARP & DOHME LLC (US) 2026-03-24 — — US disclosed
US-12552783-B2 Modulators of proteolysis and associated methods of use ARVINAS OPERATIONS, INC. (US) 2026-02-17 — — US disclosed
EP-4076460-B1 1,4-DIHYDRO-2H-SPIRO[ISOQUINOLINE-3,4'-PIPERIDINE DERIVATIVES AS PRMT5 INHIBITORS FOR THE TREATMENT OF CANCER MERCK SHARP & DOHME LLC (US) 2026-01-21 — — EP disclosed
US-12509438-B2 Pyrazole derivative APTABIO THERAPEUTICS INC. (KR) 2025-12-30 — — US disclosed
US-12441704-B2 Compounds active towards nuclear receptors NUEVOLUTION A/S (DK) 2025-10-14 — — US disclosed
US-12441730-B2 PRMT5 inhibitors MERCK SHARP & DOHME LLC (US) 2025-10-14 — — US disclosed
WO-2025094035-A1 TOLL-LIKE RECEPTOR AGONISTS AND CONJUGATES THEREOF PFIZER INC. (US) 2025-05-08 — — WO disclosed
WO-2025053850-A1 COVALENT KRAS-BINDING COMPOUNDS FOR MEDICAL TREATMENT HYKU BIOSCIENCES INC. (US) 2025-03-13 — — WO disclosed
US-20250051361-A1 5,6,7,8-TETRAHYDRO-2,6-NAPHTHYRIDINE DERIVATIVES AS CANCER THERAPEUTICS VRISE THERAPEUTICS, INC. 2025-02-13 — — US disclosed
EP-0000338-B1 ISOXAZOLO(5,4-C)PYRIDINE DERIVATIVES, THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM H.Lundbeck & Co., A/S (DK) 1981-11-25 — — EP disclosed
US-4301287-A FOR TREATMENT OF PSYCHOLOGICAL AND NERVOUS SYSTEM DISORDERS H. LUNDBECK & CO. A/S (DK) 1981-11-17 — — US disclosed
US-4278676-A NERVOUS SYSTEM DISORDERS, CYCLIZATION, HYDROLYSIS H. LUNDBECK & CO. A/S (DK) 1981-07-14 — — US disclosed
EP-0028017-A1 3-Piperidinone-4-carboxylic acid derivatives H.Lundbeck & Co., A/S (DK) 1981-05-06 — — EP disclosed
EP-0027279-A1 Isoxazolo(5,4-C)pyridines H.Lundbeck & Co., A/S (DK) 1981-04-22 — — EP disclosed
EP-0000338-A2 Isoxazolo(5,4-c)pyridine derivatives, their preparation and pharmaceutical compositions containing them H.Lundbeck & Co., A/S (DK) 1979-01-24 — — EP disclosed
US-4081449-A ANALGESICS, ANTICONVULSANTS ABBOTT LABORATORIES (US) 1978-03-28 — — US disclosed
US-RE29196-E ANALGESICS AND TRANQUILIZERS ABBOTT LABORATORIES (US) 1977-04-26 — — US disclosed
US-3962448-A CNS DEPRESSANTS, VETERINARY SMITHKLINE CORPORATION (US) 1976-06-08 — — US disclosed
US-3932432-A Alkylphenyl benzopyranopyridines ABBOTT LABORATORIES (US) 1976-01-13 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12509438-B2 Pyrazole derivative CBR3, NR3C2, NR3C1 MEN1 3044/4885KMT2A 4419/4885ALDH1A1 769/4885
US-12441704-B2 Compounds active towards nuclear receptors NCOA1, NR1H2, NCOA3 MEN1 4625/4885KMT2A 3180/4885ALDH1A1 1638/4885
US-12552783-B2 Modulators of proteolysis and associated methods of use CRBN, ADRM1, MDM2 MEN1 3384/4885KMT2A 1095/4885ALDH1A1 3965/4885
US-12441730-B2 PRMT5 inhibitors PRMT5, PRMT1, PRMT3 MEN1 993/4885KMT2A 103/4885ALDH1A1 1341/4885
US-12583871-B2 PRMT5 inhibitors PRMT5, PRMT1, PRMT3 MEN1 1361/4885KMT2A 110/4885ALDH1A1 1190/4885
US-20250051361-A1 5,6,7,8-TETRAHYDRO-2,6-NAPHTHYRIDINE DERIVATIVES AS CANCER THERAPEUTICS KRAS, NRAS, TP53 MEN1 1064/4885KMT2A 2720/4885ALDH1A1 2082/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.