SCHEMBL18423971

SCHEMBL18423971

CC(C)=CCC(C)CC(C)C=O

nearest known ligand 0.36

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
GRIK1 P39086 1/20 0.36
GRIK2 Q13002 1/20 0.36
ALOX15 P16050 3/20 0.34
TSHR P16473 1/20 0.34
ALDH1A1 P00352 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23411636 0.83 GRIK1 (0.36) GRIK1GRIK2ALOX15TSHR
SCHEMBL6084721 0.81
SCHEMBL3411682 0.77
SCHEMBL25305021 0.77 ALOX15 (0.43) GRIK1GRIK2ALOX15TSHRALDH1A1
SCHEMBL8388179 0.75 ALOX15 (0.44) GRIK1GRIK2ALOX15TSHRALDH1A1
SCHEMBL5770302 0.75 ALOX15 (0.38) GRIK1GRIK2ALOX15TSHRALDH1A1
SCHEMBL11862844 0.75 ALOX15 (0.37) GRIK1GRIK2ALOX15TSHRALDH1A1
SCHEMBL18421396 0.73 ALDH1A1 (0.40) GRIK1GRIK2ALOX15TSHRALDH1A1
SCHEMBL18425429 0.73 ALDH1A1 (0.40) GRIK1GRIK2ALOX15TSHRALDH1A1
SCHEMBL20378434 0.73 ALDH1A1 (0.40) GRIK1GRIK2ALOX15TSHRALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4065566-B1 TRPM8 MODULATORS GIVAUDAN SA (CH) 2025-01-01 EP disclosed
CN-114761385-B TRPM8 modulators 奇华顿股份有限公司 2024-10-29 CN disclosed
US-20240294470-A1 FRAGRANCE COMPOUNDS GIVAUDAN SA (CH) 2024-09-05 US disclosed
EP-4355728-A1 FRAGRANCE COMPOUNDS Givaudan SA (CH) 2024-04-24 EP disclosed
CN-117500783-A Perfume compounds 奇华顿股份有限公司 2024-02-02 CN disclosed
US-20230002334-A1 TRPM8 MODULATORS GIVAUDAN SA (CH) 2023-01-05 US disclosed
WO-2022261956-A1 FRAGRANCE COMPOUNDS GIVAUDAN SA (CH) 2022-12-22 WO disclosed
WO-2022263605-A1 FRAGRANCE COMPOUNDS GIVAUDAN SA (CH) 2022-12-22 WO disclosed
EP-4065566-A1 TRPM8 MODULATORS Givaudan SA (CH) 2022-10-05 EP disclosed
CN-114761385-A TRPM8 modulators 奇华顿股份有限公司 2022-07-15 CN disclosed
WO-2021105261-A1 TRPM8 MODULATORS GIVAUDAN SA (CH) 2021-06-03 WO disclosed
CN-107848924-B 2,4, 7-Trimethyloct-6-en-1-ol as fragrance ingredient 奇华顿股份有限公司 2021-04-02 CN disclosed
US-10400193-B2 2,4,7-trimethyloct-6-en-1-ol as fragrance ingredient GIVAUDAN S.A. (CH) 2019-09-03 US disclosed
US-20180201872-A1 2,4,7-TRIMETHYLOCT-6-EN-1-OL AS FRAGANCE INGREDIENT GIVAUDAN S.A. (CH) 2018-07-19 US disclosed
EP-3328822-A1 2,4,7-TRIMETHYLOCT-6-EN-1-OL AS FRAGANCE INGREDIENT Givaudan SA (CH) 2018-06-06 EP disclosed
CN-107848924-A The pungent alcohol of 6 alkene 1 of 2,4,7 trimethyls as fragrance component 奇华顿股份有限公司 2018-03-27 CN disclosed
WO-2017017152-A1 2,4,7-TRIMETHYLOCT-6-EN-1-OL AS FRAGANCE INGREDIENT GIVAUDAN SA (CH) 2017-02-02 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240294470-A1 FRAGRANCE COMPOUNDS FASN, FAAH2, FADS2 GRIK1 2864/4885GRIK2 2949/4885ALOX15 78/4885
US-20180201872-A1 2,4,7-TRIMETHYLOCT-6-EN-1-OL AS FRAGANCE INGREDIENT TAS2R8, OR51E2, TAS2R50 GRIK1 1947/4885GRIK2 2143/4885ALOX15 25/4885
US-10400193-B2 2,4,7-trimethyloct-6-en-1-ol as fragrance ingredient ENO1, OR51E2, THOC2 GRIK1 2033/4885GRIK2 2475/4885ALOX15 8/4885
US-20230002334-A1 TRPM8 MODULATORS TRPM8, TRPM7, TRPM2 GRIK1 586/4885GRIK2 668/4885ALOX15 2537/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.