Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 4/20 | 0.62 |
| ▸ | PTBP1 | P26599 | 1/20 | 0.62 |
| ▸ | HTT | P42858 | 1/20 | 0.62 |
| ▸ | KLF5 | Q13887 | 1/20 | 0.62 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.62 |
| ▸ | NAMPT | P43490 | 8/20 | 0.62 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.58 |
| ▸ | GRM4 | Q14833 | 1/20 | 0.54 |
| ▸ | MEN1 | O00255 | 2/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.54 |
| ▸ | PRKCI | P41743 | 1/20 | 0.54 |
| ▸ | KDM1A | O60341 | 1/20 | 0.53 |
| ▸ | RCOR1 | Q9UKL0 | 1/20 | 0.53 |
| ▸ | CYP11B1 | P15538 | 3/20 | 0.52 |
| ▸ | CYP11B2 | P19099 | 3/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.52 |
| ▸ | HPGD | P15428 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL168594 | 0.84 | GRM4 (0.63) | LMNAHTTSMN1; SMN2GRM4MEN1 | |
| SCHEMBL12412142 | 0.82 | GRM5 (0.58) | SMN1; SMN2KMT2A | |
| SCHEMBL21595564 | 0.82 | ATG4B (0.56) | LMNAPTBP1HTTKLF5SMN1; SMN2 | |
| SCHEMBL30763180 | 0.82 | ATG4B (0.56) | LMNAPTBP1HTTKLF5SMN1; SMN2 | |
| SCHEMBL12181073 | 0.81 | ALDH1A1 (0.58) | HTTSMN1; SMN2GRM4MEN1KMT2A | |
| SCHEMBL5164235 | 0.80 | GRM4 (0.59) | LMNAHTTSMN1; SMN2GRM4MEN1 | |
| SCHEMBL11883609 | 0.78 | LMNA (0.56) | LMNAPTBP1HTTKLF5SMN1; SMN2 | |
| SCHEMBL31261631 | 0.78 | NAMPT (0.72) | LMNAPTBP1HTTKLF5SMN1; SMN2 | |
| SCHEMBL6669304 | 0.77 | HTT (1.00) | LMNAPTBP1HTTKLF5SMN1; SMN2 | |
| SCHEMBL13164049 | 0.77 | NAMPT (1.00) | LMNAPTBP1HTTKLF5SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3810597-B1 | 1,2,4-TRIAZOLE DERIVATIVES AS TANKYRASE INHIBITORS | UNIV OSLO HF (NO) | 2025-11-26 | — | — | EP | disclosed |
| US-11926614-B2 | 1,2,4-triazole derivatives as tankyrase inhibitors | OSLO UNIVERSITETSSYKEHUS HF (NO) | 2024-03-12 | — | — | US | disclosed |
| CN-112469714-B | 1,2, 4-triazole derivatives as tankyrase inhibitors | 奥斯陆大学国家医院 | 2024-03-01 | — | — | CN | disclosed |
| EP-3810597-A1 | 1,2,4-TRIAZOLE DERIVATIVES AS TANKYRASE INHIBITORS | Oslo Universitetssykehus HF (NO) | 2021-04-28 | — | — | EP | disclosed |
| WO-2019243822-A1 | 1,2,4-TRIAZOLE DERIVATIVES AS TANKYRASE INHIBITORS | OSLO UNIVERSITETSSYKEHUS HF (NO) | 2019-12-26 | — | — | WO | disclosed |
| US-20150368236-A1 | 2-(PYRIDIN-3-YL)-5-HETARYL-THIAZOLE COMPOUNDS CARRYING AN IMINE OR IMINE-DERIVED SUBSTITUENT FOR COMBATING INVERTEBRATE PESTS | BASF SE (DE) | 2015-12-24 | — | — | US | disclosed |
| EP-2938611-A1 | 2-(PYRIDIN-3-YL)-5-HETARYL-THIAZOLE COMPOUNDS CARRYING AN IMINE OR IMINE-DERIVED SUBSTITUENT FOR COMBATING INVERTEBRATE PESTS | BASF SE (DE) | 2015-11-04 | — | — | EP | disclosed |
| US-20150166528-A1 | Pesticidal methods using substituted 3-pyridyl thiazole compounds and derivatives for combating animal pests | BASF SE (DE) | 2015-06-18 | — | — | US | disclosed |
| EP-2863738-A2 | PESTICIDAL METHODS USING SUBSTITUTED 3-PYRIDYL THIAZOLE COMPOUNDS AND DERIVATIVES FOR COMBATING ANIMAL PESTS | BASF SE (DE) | 2015-04-29 | — | — | EP | disclosed |
| US-20140296064-A1 | PESTICIDAL METHODS USING SUBSTITUTED 3-PYRIDYL THIAZOLE COMPOUNDS AND DERIVATIVES FOR COMBATING ANIMAL PESTS I | BASF SE (DE) | 2014-10-02 | — | — | US | disclosed |
| US-20140249024-A1 | Pesticidal Methods Using Substituted 3-pyridyl Thiazole Compounds and Derivatives for Combating Animal Pests II | BASF SE (DE) | 2014-09-04 | — | — | US | disclosed |
| WO-2014102244-A1 | 2-(PYRIDIN-3-YL)-5-HETARYL-THIAZOLE COMPOUNDS CARRYING AN IMINE OR IMINE-DERIVED SUBSTITUENT FOR COMBATING INVERTEBRATE PESTS | BASF SE (DE) | 2014-07-03 | — | — | WO | disclosed |
| WO-2014102245-A1 | CYANO-SUBSTITUTED 2-(PYRIDIN-3-YL)-5-HETARYL-THIAZOLE COMPOUNDS FOR COMBATING INVERTEBRATE PESTS | BASF SE (DE) | 2014-07-03 | — | — | WO | disclosed |
| EP-2731427-A2 | PESTICIDAL METHODS USING SUBSTITUTED 3-PYRIDYL THIAZOLE COMPOUNDS AND DERIVATIVES FOR COMBATING ANIMAL PESTS I | BASF SE (DE) | 2014-05-21 | — | — | EP | disclosed |
| EP-2731426-A2 | PESTICIDAL METHODS USING SUBSTITUTED 3-PYRIDYL THIAZOLE COMPOUNDS AND DERIVATIVES FOR COMBATING ANIMAL PESTS II | BASF SE (DE) | 2014-05-21 | — | — | EP | disclosed |
| WO-2013186089-A2 | PESTICIDAL METHODS USING SUBSTITUTED 3-PYRIDYL THIAZOLE COMPOUNDS AND DERIVATIVES FOR COMBATING ANIMAL PESTS | BASF SE (DE) | 2013-12-19 | — | — | WO | disclosed |
| EP-2320737-B1 | PYRAZOLO-[1,5-A]-PYRIDINES AS MARK INHIBITORS | MERCK SHARP & DOHME (US) | 2013-07-17 | — | — | EP | disclosed |
| WO-2013010947-A2 | PESTICIDAL METHODS USING SUBSTITUTED 3-PYRIDYL THIAZOLE COMPOUNDS AND DERIVATIVES FOR COMBATING ANIMAL PESTS II | BASF SE (DE) | 2013-01-24 | — | — | WO | disclosed |
| WO-2013010946-A2 | PESTICIDAL METHODS USING SUBSTITUTED 3-PYRIDYL THIAZOLE COMPOUNDS AND DERIVATIVES FOR COMBATING ANIMAL PESTS I | BASF SE (DE) | 2013-01-24 | — | — | WO | disclosed |
| EP-2320737-A1 | PYRAZOLOÝ1,5-A¨PYRIDINES AS MARK INHIBITORS | Merck & Co., Inc. (US) | 2011-05-18 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150368236-A1 | 2-(PYRIDIN-3-YL)-5-HETARYL-THIAZOLE COMPOUNDS CARRYING AN IMINE OR IMINE-DERIVED SUBSTITUENT FOR COMBATING INVERTEBRATE PESTS | PIR, NT5C, NT5M | LMNA 769/4885PTBP1 1758/4885HTT 42/4885 |
| US-20140249024-A1 | Pesticidal Methods Using Substituted 3-pyridyl Thiazole Compounds and Derivatives for Combating Animal Pests II | PTMS, PNPO, THOP1 | LMNA 2176/4885PTBP1 2234/4885HTT 3035/4885 |
| US-20150166528-A1 | Pesticidal methods using substituted 3-pyridyl thiazole compounds and derivatives for combating animal pests | PTMS, PDXK, TH | LMNA 2163/4885PTBP1 2476/4885HTT 2557/4885 |
| US-11926614-B2 | 1,2,4-triazole derivatives as tankyrase inhibitors | GBA3, CBR3, TECR | LMNA 1564/4885PTBP1 1446/4885HTT 3315/4885 |
| US-20140296064-A1 | PESTICIDAL METHODS USING SUBSTITUTED 3-PYRIDYL THIAZOLE COMPOUNDS AND DERIVATIVES FOR COMBATING ANIMAL PESTS I | PTMS, THOP1, TH | LMNA 2147/4885PTBP1 2125/4885HTT 3035/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.