SCHEMBL18502290

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL18502273	0.96	ALDH1A1 (0.35)	G6PDPRF1LIMK1FLT3CA1
	SCHEMBL18502379	0.93	G6PD (0.36)	G6PDPRF1LIMK1APPCA1
	SCHEMBL18502372	0.91	G6PD (0.35)	G6PDPRF1LIMK1APPCA1
	SCHEMBL18502362	0.90	G6PD (0.36)	G6PDPRF1LIMK1APPCA1
	SCHEMBL18502321	0.90	G6PD (0.34)	G6PDPRF1LIMK1APPPTGER4
	SCHEMBL18502268	0.89	ALOX5 (0.34)	G6PDPRF1CA1CA2KDM4E
	SCHEMBL18507909	0.88	G6PD (0.35)	G6PDPRF1CA1CA2PTGER4
	SCHEMBL18502376	0.88	G6PD (0.36)	G6PDPRF1CA1CA2KDM4E
	SCHEMBL21992225	0.88	G6PD (0.31)	G6PD
	SCHEMBL18502314	0.87	G6PD (0.34)	G6PDPRF1APPPTGER4ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 21 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (8 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.