Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDO1 | P14902 | 1/20 | 0.49 |
| ▸ | TDO2 | P48775 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.46 |
| ▸ | MGLL | Q99685 | 1/20 | 0.44 |
| ▸ | NOTUM | Q6P988 | 2/20 | 0.44 |
| ▸ | FLT3 | P36888 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | MPO | P05164 | 1/20 | 0.42 |
| ▸ | PKM | P14618 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16490944 | 0.85 | IDO1 (0.37) | IDO1TDO2ALDH1A1KDM4EMGLL | |
| SCHEMBL18504503 | 0.83 | CYP1A2 (0.56) | IDO1TDO2ALDH1A1MGLLMAPT | |
| SCHEMBL2611119 | 0.82 | SMN1; SMN2 (0.43) | ALDH1A1NOTUMPOLBHTT | |
| SCHEMBL1942309 | 0.81 | ADRA2C (0.45) | ALDH1A1KDM4EKMT2AMAPTPOLB | |
| SCHEMBL18504528 | 0.81 | FAAH (0.46) | IDO1TDO2ALDH1A1MGLLKMT2A | |
| SCHEMBL22563846 | 0.81 | GSK3A (0.49) | ALDH1A1MGLLKMT2APOLBL3MBTL1 | |
| SCHEMBL18503912 | 0.81 | IDO1 (0.50) | IDO1TDO2ALDH1A1MGLLNOTUM | |
| SCHEMBL2611112 | 0.80 | PTGS2 (0.46) | IDO1TDO2ALDH1A1MGLLNOTUM | |
| SCHEMBL15790778 | 0.80 | RAB9A (0.55) | ALDH1A1KDM4EMGLLNOTUMKMT2A | |
| SCHEMBL8301872 | 0.80 | ALDH1A1 (0.51) | IDO1TDO2ALDH1A1MAPTGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2841429-B1 | TETRAZOLINONE COMPOUNDS AND ITS USE AS PESTICIDES | SUMITOMO CHEMICAL CO (JP) | 2020-10-21 | — | — | EP | disclosed |
| US-9565856-B2 | Tetrazolinone compounds and its use as pesticides | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2017-02-14 | — | — | US | disclosed |