Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FAAH | O00519 | 1/20 | 0.46 |
| ▸ | MGLL | Q99685 | 1/20 | 0.46 |
| ▸ | MPO | P05164 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | MPI | P34949 | 1/20 | 0.38 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.37 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.36 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | TP53 | P04637 | 2/20 | 0.35 |
| ▸ | IDO1 | P14902 | 4/20 | 0.35 |
| ▸ | TDO2 | P48775 | 4/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | BCHE | P06276 | 1/20 | 0.33 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16490950 | 0.84 | FAAH (0.33) | FAAHMGLLCYP1A2POLBCYP3A4 | |
| SCHEMBL18504503 | 0.81 | CYP1A2 (0.56) | MGLLCYP1A2POLBCYP3A4ALDH1A1 | |
| SCHEMBL18504499 | 0.81 | IDO1 (0.49) | MGLLMPOPOLBALDH1A1LMNA | |
| SCHEMBL18503912 | 0.80 | IDO1 (0.50) | FAAHMGLLCYP1A2POLBCYP3A4 | |
| SCHEMBL1942309 | 0.80 | ADRA2C (0.45) | CYP1A2POLBCYP3A4ALDH1A1MAPT | |
| SCHEMBL22563846 | 0.80 | GSK3A (0.49) | MGLLCYP1A2POLBCYP3A4KEAP1 | |
| SCHEMBL15790778 | 0.79 | RAB9A (0.55) | MGLLCYP1A2POLBALDH1A1LMNA | |
| SCHEMBL8301872 | 0.78 | ALDH1A1 (0.51) | NFE2L2ALDH1A1MAPTTP53IDO1 | |
| SCHEMBL18500952 | 0.78 | MGLL (0.51) | MGLLCYP1A2POLBCYP3A4ALDH1A1 | |
| SCHEMBL18504308 | 0.78 | ALOX5 (0.43) | CYP1A2POLBCYP3A4HSD11B1KEAP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2841429-B1 | TETRAZOLINONE COMPOUNDS AND ITS USE AS PESTICIDES | SUMITOMO CHEMICAL CO (JP) | 2020-10-21 | — | — | EP | disclosed |
| US-9565856-B2 | Tetrazolinone compounds and its use as pesticides | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2017-02-14 | — | — | US | disclosed |