Piperidine

Piperidine

SCHEMBL18526795

C1CCNCC1.N.O

nearest known ligand 0.00

Full drug profile on Sugi Atlas →

Known targets — ChEMBL curated mechanism

ABCC9ABL1ACEACHEACVR1ADORA1ADORA2AADORA2BADORA3ADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB1ADRB2ADRB3AGTR1ALOX5ATP4AATP4BBCRBTKCACNA1ACACNA1BCACNA1CCACNA1DCACNA1ECACNA1FCACNA1GCACNA1HCACNA1ICACNA1SCACNA2D1CACNA2D2CACNA2D3CACNA2D4CACNB1CACNB2CACNB3CACNB4CACNG1CACNG2CACNG3CACNG4CACNG5CACNG6CACNG7CACNG8CALCRLCFBCHRM1CHRM2CHRM3CHRM4CHRM5CHRNA1CHRNB1CHRNDCHRNECHRNGCRBNCUL4ACXCR1CXCR2DDB1DDCDHFRDPP4DRD2DRD3DRD4EGFRERBB2ERBB4ESR1ESR2FDPSFKBP1AFLT1FLT3FLT4GARTGHSRGRIA1GRIA2GRIA3GRIA4GRIK1GRIK2GRIK3GRIK4GRIK5GRIN2AGSK3AGSK3BHDAC1HDAC10HDAC11HDAC2HDAC3HDAC4HDAC5HDAC6HDAC7HDAC8HDAC9HRH1HTR1AHTR1BHTR1DHTR1EHTR1FHTR2AHTR2BHTR2CHTR3AHTR3BHTR3CHTR3DHTR3EHTR4HTR5AHTR6HTR7IDH1IDH2IMPA1ITGA2BITGB3JAK1JAK2JAK3KCNJ11KCNK3KCNK9KDRKITMEN1METMMP1MMP13MMP7MMP8NANOD2NS5bODC1OPG057OPRD1OPRK1OPRM1PPARP1PARP2PDE3APDE3BPDE4APDE4BPDE4CPDE4DPDGFRBPIK3CAPIK3CBPIK3CDPIK3CGPIK3R1PIK3R2PIK3R3PIK3R5PKLRPPARDPPATPTGS1PTGS2RBX1ROCK1ROCK2RRM1RRM2RRM2BSCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASCNN1ASCNN1BSCNN1GSIGMAR1SLC10A2SLC5A2SLC6A2SLC6A3SLC6A4SLC9A3SYKTACR1THRATHRBTOP1TUBA1ATUBA1BTUBA1CTUBA3CTUBA3ETUBA4ATUBBTUBB1TUBB2ATUBB2BTUBB3TUBB4ATUBB4BTUBB6TUBB8TYK2TYMSVDRampCblablaT-3blaT-4blaT-5blaT-6blaUOE-1dacAdacBdacCfolAfolPftsIgyrAgyrBileSmecAmrcAmrcBmrdAparCparEpbp2pbp4pbpApbpFrplArplBrplCrplDrplErplFrplIrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmE2rpmFrpmGrpmG1rpmG2rpmG3rpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUthyAykgMykgO

The experimentally established mechanism targets of Piperidine. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Azepane SCHEMBL29258022 1.00
Azepane SCHEMBL2485654 1.00 ALDH1A1 (0.82)
Piperidine SCHEMBL28700802 0.95 ALDH1A1 (0.90)
Azepane SCHEMBL20563677 0.95
Piperidine SCHEMBL8944121 0.95
Pyrrolidine SCHEMBL28458206 0.95
Piperidine SCHEMBL7575332 0.95
Piperidine SCHEMBL4616564 0.95
Piperidine SCHEMBL7575329 0.95 ALDH1A1 (0.90)
Azepane SCHEMBL3654409 0.95

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 45 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-113527543-B Aqueous neutral piperidine nitrogen-oxygen free radical organic flow battery electrolyte, battery and preparation method 西安交通大学 2022-12-09 CN claimed
CN-113527543-A Aqueous neutral piperidine nitrogen-oxygen free radical organic flow battery electrolyte, battery and preparation method 西安交通大学 2021-10-22 CN claimed
CN-110183899-A UV snowflake printing ink 湖南省浩彩新材料科技有限公司 2019-08-30 CN claimed
CN-105622712-B A kind of steroidal 3- ketone -4- alkene object synthesis technology 天津金耀集团有限公司 2019-08-27 CN claimed
CN-107955033-A Solar cell EVA encapsulating films are used to prepare with silane coupled agent and process for producing same 湖北华欣有机硅新材料有限公司 2018-04-24 CN claimed
CN-104725414-B The preparation method of trialkyl silicon substrate acrylate or trialkyl silicon substrate methacrylate 常熟市常吉化工有限公司 2018-03-16 CN claimed
CN-105543886-B The electrochemical catalysis synthetic method of aromatic nitriles 浙江工业大学 2017-08-01 CN claimed
CN-106554244-A For the high temperature modification compound polymerization inhibitor in aromatic olefin monomers distillation process and its application 中国石油化工股份有限公司 2017-04-05 CN claimed
US-9598429-B2 Method for synthesizing Milbemycin oxime HUBEI HONCH PHARMACEUTICAL CO., LTD (CN) 2017-03-21 US claimed
US-20170050977-A1 METHOD FOR SYNTHESIZING MILBEMYCIN OXIME HUBEI HONCH PHARMACEUTICAL CO.,LTD (CN) 2017-02-23 US claimed
CN-104418342-B A kind of TS-1 HTS and its preparation method and application 中触媒新材料股份有限公司 2016-06-15 CN claimed
CN-104418342-A TS-1 titanium silicalite molecular sieve, and preparation method and application thereof DALIAN HETEROGENEOUS CATALYST CO LTD 2015-03-18 CN claimed
CN-116895813-B Symmetrical water system neutral flow battery taking piperidine nitroxide free radical as difunctional redox pair 哈尔滨工业大学 2024-06-21 CN disclosed
CN-116895813-A Symmetrical water system neutral flow battery taking piperidine nitroxide free radical as difunctional redox pair 哈尔滨工业大学 2023-10-17 CN disclosed
CN-115974770-A Method and reaction system for preparing 2,2,6,6-tetramethyl piperidine nitroxide free radical compound and obtained product 中国石油化工股份有限公司 2023-04-18 CN disclosed
CN-113527543-B Aqueous neutral piperidine nitrogen-oxygen free radical organic flow battery electrolyte, battery and preparation method 西安交通大学 2022-12-09 CN disclosed
CN-105153421-A Method for preparing tetramethyl-1-piperidine-N-oxyl free radical polymer UNIV LIAONING SHIHUA 2015-12-16 CN disclosed
CN-104418342-A TS-1 titanium silicalite molecular sieve, and preparation method and application thereof DALIAN HETEROGENEOUS CATALYST CO LTD 2015-03-18 CN disclosed
CN-1709874-A Piperidine nitroxide free-radical derivative and its use UNIV HUADONG TECHNOLOGY (CN) 2005-12-21 CN disclosed
CN-1041598-A The phosphorous acid that stopper is used (2,2,6, the 6-tetramethyl piperidine nitrogen oxygen free radical) mixed ester and industrial process thereof BEIJING ASISTANT INST (CN) 1990-04-25 CN disclosed