Piperidine

Piperidine

SCHEMBL7575332

C1CCNCC1.O.O

nearest known ligand 0.00

Full drug profile on Sugi Atlas →

Known targets — ChEMBL curated mechanism

ABCC9ABL1ACEACHEACVR1ADORA1ADORA2AADORA2BADORA3ADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB1ADRB2ADRB3AGTR1ALOX5ATP4AATP4BBCRBTKCACNA1ACACNA1BCACNA1CCACNA1DCACNA1ECACNA1FCACNA1GCACNA1HCACNA1ICACNA1SCACNA2D1CACNA2D2CACNA2D3CACNA2D4CACNB1CACNB2CACNB3CACNB4CACNG1CACNG2CACNG3CACNG4CACNG5CACNG6CACNG7CACNG8CALCRLCFBCHRM1CHRM2CHRM3CHRM4CHRM5CHRNA1CHRNB1CHRNDCHRNECHRNGCRBNCUL4ACXCR1CXCR2DDB1DDCDHFRDPP4DRD2DRD3DRD4EGFRERBB2ERBB4ESR1ESR2FDPSFKBP1AFLT1FLT3FLT4GARTGHSRGRIA1GRIA2GRIA3GRIA4GRIK1GRIK2GRIK3GRIK4GRIK5GRIN2AGSK3AGSK3BHDAC1HDAC10HDAC11HDAC2HDAC3HDAC4HDAC5HDAC6HDAC7HDAC8HDAC9HRH1HTR1AHTR1BHTR1DHTR1EHTR1FHTR2AHTR2BHTR2CHTR3AHTR3BHTR3CHTR3DHTR3EHTR4HTR5AHTR6HTR7IDH1IDH2IMPA1ITGA2BITGB3JAK1JAK2JAK3KCNJ11KCNK3KCNK9KDRKITMEN1METMMP1MMP13MMP7MMP8NANOD2NS5bODC1OPG057OPRD1OPRK1OPRM1PPARP1PARP2PDE3APDE3BPDE4APDE4BPDE4CPDE4DPDGFRBPIK3CAPIK3CBPIK3CDPIK3CGPIK3R1PIK3R2PIK3R3PIK3R5PKLRPPARDPPATPTGS1PTGS2RBX1ROCK1ROCK2RRM1RRM2RRM2BSCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASCNN1ASCNN1BSCNN1GSIGMAR1SLC10A2SLC5A2SLC6A2SLC6A3SLC6A4SLC9A3SYKTACR1THRATHRBTOP1TUBA1ATUBA1BTUBA1CTUBA3CTUBA3ETUBA4ATUBBTUBB1TUBB2ATUBB2BTUBB3TUBB4ATUBB4BTUBB6TUBB8TYK2TYMSVDRampCblablaT-3blaT-4blaT-5blaT-6blaUOE-1dacAdacBdacCfolAfolPftsIgyrAgyrBileSmecAmrcAmrcBmrdAparCparEpbp2pbp4pbpApbpFrplArplBrplCrplDrplErplFrplIrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmE2rpmFrpmGrpmG1rpmG2rpmG3rpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUthyAykgMykgO

The experimentally established mechanism targets of Piperidine. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Water SCHEMBL27684596 1.00 ALDH1A1 (0.90)
Azepane SCHEMBL20563677 1.00
Water SCHEMBL27684593 1.00 ALDH1A1 (0.90)
Piperidine SCHEMBL4616564 1.00
Piperidine SCHEMBL7575329 1.00 ALDH1A1 (0.90)
Piperidine SCHEMBL781392 1.00 ALDH1A1 (0.90)
Piperidine SCHEMBL28700802 1.00 ALDH1A1 (0.90)
Azepane SCHEMBL29258022 0.95
Piperidine SCHEMBL9028300 0.95
Piperidine SCHEMBL30996101 0.95 ALDH1A1 (0.82)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-104245585-A Process for preparing aluminosilicate zeolite SSZ-33 CHEVRON USA INC 2014-12-24 CN disclosed
EP-0659685-B1 Epoxidation process and catalyst therefor ARCO CHEM TECH (US) 2002-03-27 EP disclosed
EP-1151999-A2 Epoxidation process and catalyst therefore ARCO Chemical Technology, L.P. (US) 2001-11-07 EP disclosed
US-5681789-A Activation of as-synthesized titanium-containing zeolites ARCO CHEMICAL TECHNOLOGY, L.P. (US) 1997-10-28 US disclosed
US-5621122-A REACTING OLEFIN WITH A HYDROPEROXIDE USING ALUMINUM-FREE, SILICA-TITANIA MOLECULAR SIEVE OXIDATION CATALYST WHICH IS ISOMORPHOUS TO ZEOLITE TYPE BETA ARCO CHEMICAL TECHNOLOGY, L.P. (US) 1997-04-15 US disclosed
US-5527520-A Method of making a titanium-containing molecular sieve ARCO CHEMICAL TECHNOLOGY, L. P. (US) 1996-06-18 US disclosed
CN-1113454-A Epoxidation process and catalyst therefore ARCO CHEM TECH (US) 1995-12-20 CN disclosed
US-5453511-A Template for preparation of silica-titania molecular sieves, epoxidation catalysts ARCO CHEMICAL TECHNOLOGY, L.P. (US) 1995-09-26 US disclosed
EP-0659685-A1 Epoxidation process and catalyst therefor ARCO Chemical Technology, L.P. (US) 1995-06-28 EP disclosed