Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MLYCD | O95822 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | PPARG | P37231 | 3/20 | 0.44 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.44 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.43 |
| ▸ | GCGR | P47871 | 6/20 | 0.43 |
| ▸ | PLG | P00747 | 1/20 | 0.43 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.43 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.43 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | TP53BP1 | Q12888 | 1/20 | 0.41 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.41 |
| ▸ | FAAH | O00519 | 1/20 | 0.41 |
| ▸ | NAAA | Q02083 | 1/20 | 0.41 |
| ▸ | GIPR | P48546 | 1/20 | 0.41 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.41 |
| ▸ | PPARD | Q03181 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1853396 | 0.90 | MLYCD (0.47) | MLYCDALDH1A1POLBPPARGEPHX2 | |
| SCHEMBL1852984 | 0.80 | MLYCD (0.51) | MLYCDALDH1A1PPARGEPHX2GCGR | |
| SCHEMBL6022126 | 0.79 | ALDH1A1 (0.46) | MLYCDALDH1A1POLBMRGPRX4GCGR | |
| SCHEMBL5039508 | 0.78 | ROCK2 (0.44) | MLYCDPPARGEPHX2GCGRNAAA | |
| SCHEMBL1853034 | 0.77 | TMEM97 (0.47) | MLYCDALDH1A1POLBMRGPRX4L3MBTL1 | |
| SCHEMBL5039660 | 0.76 | HDAC1 (0.44) | MLYCDALDH1A1POLBPPARGEPHX2 | |
| SCHEMBL5047162 | 0.76 | HDAC1 (0.44) | MLYCDALDH1A1POLBPPARGEPHX2 | |
| SCHEMBL1852697 | 0.74 | MLYCD (0.58) | MLYCDALDH1A1POLBMRGPRX4L3MBTL1 | |
| SCHEMBL5048862 | 0.73 | ALDH1A1 (0.56) | MLYCDALDH1A1POLBMRGPRX4LMNA | |
| SCHEMBL2358408 | 0.73 | POLB (0.80) | MLYCDALDH1A1POLBMRGPRX4L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1470102-B1 | SUBSTITUTED METHYLENE AMIDE DERIVATIVES AS MODULATORS OF PROTEIN TYROSINE PHOSPHATASES (PTPS) | MERCK SERONO SA (CH) | 2011-05-25 | — | — | EP | disclosed |