SCHEMBL18566652

SCHEMBL18566652

Fc1ccc2c(c1)C1(c3ccccc3-2)c2cc(Br)ccc2-c2c1cc(Br)c1c2oc2ccccc21

nearest known ligand 0.34

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PDK2 Q15119 2/20 0.34
NMUR2 Q9GZQ4 2/20 0.34
AKR1A1 P14550 1/20 0.34
AKR1B1 P15121 1/20 0.34
PIM1 P11309 1/20 0.32
CSNK2A2 P19784 1/20 0.32
CSNK2B P67870 1/20 0.32
PIM3 Q86V86 1/20 0.32
PIM2 Q9P1W9 1/20 0.32
GABRP O00591 1/20 0.31
GABRD O14764 1/20 0.31
GABRA1 P14867 1/20 0.31
GABRB1 P18505 1/20 0.31
GABRG2 P18507 1/20 0.31
GABRB3 P28472 1/20 0.31
GABRA5 P31644 1/20 0.31
GABRA3 P34903 1/20 0.31
GABRA2 P47869 1/20 0.31
GABRB2 P47870 1/20 0.31
GABRA4 P48169 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25577342 1.00 PDK2 (0.34) PDK2NMUR2AKR1A1AKR1B1PIM1
SCHEMBL29776674 1.00 PDK2 (0.34) PDK2NMUR2AKR1A1AKR1B1PIM1
SCHEMBL18926653 0.96 PDK2 (0.35) PDK2NMUR2ALOX5CDC14BCDC14A
SCHEMBL18927383 0.96 PDK2 (0.35) PDK2NMUR2ALOX5CDC14BCDC14A
SCHEMBL18165293 0.94 PDK2 (0.36) PDK2NMUR2GABRPGABRDGABRA1
SCHEMBL29776716 0.94 PDK2 (0.36) PDK2NMUR2GABRPGABRDGABRA1
SCHEMBL18926675 0.89 CDC14B (0.34) PDK2NMUR2GABRPGABRDGABRA1
SCHEMBL22004942 0.89 PDK2 (0.33) PDK2ALOX5CDC14BCDC14A
SCHEMBL21031045 0.88 AHR (0.33) PDK2NMUR2AKR1A1AKR1B1PIM1
SCHEMBL18854839 0.87 ALOX5 (0.36) ALOX5CDC14BCDC14A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 26 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3255692-B1 ORGANIC ELECTROLUMINESCENT ELEMENT HODOGAYA CHEMICAL CO LTD (JP) 2023-07-05 EP disclosed
US-11683980-B2 Condensed fluorene derivative comprising heterocyclic ring SFC CO., LTD. (KR) 2023-06-20 US disclosed
US-11683980-B2 Condensed fluorene derivative comprising heterocyclic ring SFC CO., LTD. (KR) 2023-06-20 US disclosed
US-11672172-B2 Heterocyclic compound comprising aromatic amine group and organic light-emitting diode including the same SFC CO., LTD. (KR) 2023-06-06 US disclosed
US-11672172-B2 Heterocyclic compound comprising aromatic amine group and organic light-emitting diode including the same SFC CO., LTD. (KR) 2023-06-06 US disclosed
EP-4116297-A1 CONDENSED FLUORENE DERIVATIVE COMPRISING HETEROCYCLIC RING SFC Co., Ltd. (KR) 2023-01-11 EP disclosed
EP-3223330-B1 ORGANIC ELECTROLUMINESCENT DEVICE HODOGAYA CHEMICAL CO LTD (JP) 2022-02-23 EP disclosed
US-11158811-B2 Organic electroluminescent device HODOGAYA CHEMICAL CO., LTD. (JP) 2021-10-26 US disclosed
EP-3144302-B1 HETEROCYCLIC COMPOUND CONTAINING AROMATIC AMINE GROUP, AND ORGANIC LIGHT-EMITTING DEVICE COMPRISING SAME SFC CO LTD (KR) 2021-10-06 EP disclosed
EP-3240057-B1 ORGANIC ELECTROLUMINESCENT ELEMENT HODOGAYA CHEMICAL CO LTD (JP) 2021-04-07 EP disclosed
US-20170346009-A1 ORGANIC ELECTROLUMINESCENT DEVICE SFC CO., LTD. (KR) 2017-11-30 US disclosed
EP-3240057-A1 ORGANIC ELECTROLUMINESCENT ELEMENT Hodogaya Chemical Co., Ltd. (JP) 2017-11-01 EP disclosed
EP-3223330-A1 ORGANIC ELECTROLUMINESCENT ELEMENT Hodogaya Chemical Co., Ltd. (JP) 2017-09-27 EP disclosed
US-20170222155-A1 CONDENSED FLUORENE DERIVATIVE COMPRISING HETEROCYCLIC RING SFC CO., LTD. (KR) 2017-08-03 US disclosed
US-20170222155-A1 CONDENSED FLUORENE DERIVATIVE COMPRISING HETEROCYCLIC RING SFC CO., LTD. (KR) 2017-08-03 US disclosed
US-20170207395-A1 ORGANIC ELECTROLUMINESCENT DEVICE HODOGAYA CHEMICAL CO., LTD. (JP) 2017-07-20 US disclosed
EP-3176158-A2 CONDENSED FLUORENE DERIVATIVE COMPRISING HETERO RING SFC Co., Ltd. (KR) 2017-06-07 EP disclosed
EP-3144302-A1 HETEROCYCLIC COMPOUND CONTAINING AROMATIC AMINE GROUP, AND ORGANIC LIGHT-EMITTING DEVICE COMPRISING SAME SFC Co., Ltd. (KR) 2017-03-22 EP disclosed
US-20170062729-A1 HETEROCYCLIC COMPOUND COMPRISING AROMATIC AMINE GROUP AND ORGANIC LIGHT-EMITTING DIODE INCLUDING THE SAME SFC CO., LTD. (KR) 2017-03-02 US disclosed
US-20170062729-A1 HETEROCYCLIC COMPOUND COMPRISING AROMATIC AMINE GROUP AND ORGANIC LIGHT-EMITTING DIODE INCLUDING THE SAME SFC CO., LTD. (KR) 2017-03-02 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20170222155-A1 CONDENSED FLUORENE DERIVATIVE COMPRISING HETEROCYCLIC RING CCNE2, INF2, AFF4 PDK2 2097/4885NMUR2 2456/4885AKR1A1 4184/4885
US-11683980-B2 Condensed fluorene derivative comprising heterocyclic ring CCNE2, INF2, AFF4 PDK2 2097/4885NMUR2 2456/4885AKR1A1 4184/4885
US-20170346009-A1 ORGANIC ELECTROLUMINESCENT DEVICE AHR, SLC18A1, ARNT PDK2 1466/4885NMUR2 2420/4885AKR1A1 1494/4885
US-20170062729-A1 HETEROCYCLIC COMPOUND COMPRISING AROMATIC AMINE GROUP AND ORGANIC LIGHT-EMITTING DIODE INCLUDING THE SAME DDC, TYR, AOC2 PDK2 2099/4885NMUR2 1093/4885AKR1A1 3100/4885
US-20170207395-A1 ORGANIC ELECTROLUMINESCENT DEVICE KCNN2, SLC7A5, KCNH3 PDK2 1512/4885NMUR2 3222/4885AKR1A1 2923/4885
US-11672172-B2 Heterocyclic compound comprising aromatic amine group and organic light-emitting diode including the same DDC, TYR, AOC2 PDK2 2099/4885NMUR2 1093/4885AKR1A1 3100/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.