SCHEMBL18165293

SCHEMBL18165293

Brc1ccc2c(c1)C1(c3ccccc3-c3ccccc31)c1cc(Br)c3c(oc4ccccc43)c1-2

nearest known ligand 0.36

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PDK2 Q15119 1/20 0.36
ALOX5 P09917 1/20 0.34
NMUR2 Q9GZQ4 2/20 0.33
CDC14B O60729 1/20 0.31
CDC14A Q9UNH5 1/20 0.31
TNKS O95271 1/20 0.30
GABRP O00591 1/20 0.30
GABRD O14764 1/20 0.30
GABRA1 P14867 1/20 0.30
GABRB1 P18505 1/20 0.30
GABRG2 P18507 1/20 0.30
GABRB3 P28472 1/20 0.30
GABRA5 P31644 1/20 0.30
GABRA3 P34903 1/20 0.30
GABRA2 P47869 1/20 0.30
GABRB2 P47870 1/20 0.30
GABRA4 P48169 1/20 0.30
GABRE P78334 1/20 0.30
GABRA6 Q16445 1/20 0.30
GABRG1 Q8N1C3 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29776716 1.00 PDK2 (0.36) PDK2ALOX5NMUR2CDC14BCDC14A
SCHEMBL21031045 0.94 AHR (0.33) PDK2ALOX5NMUR2
SCHEMBL18566652 0.94 PDK2 (0.34) PDK2ALOX5NMUR2CDC14BCDC14A
SCHEMBL29776674 0.94 PDK2 (0.34) PDK2ALOX5NMUR2CDC14BCDC14A
SCHEMBL25577342 0.94 PDK2 (0.34) PDK2ALOX5NMUR2CDC14BCDC14A
SCHEMBL18854839 0.93 ALOX5 (0.36) ALOX5CDC14BCDC14A
SCHEMBL18566647 0.91 PDK2 (0.36) PDK2ALOX5NMUR2CDC14BCDC14A
SCHEMBL18926867 0.90 MAOA (0.32) PDK2ALOX5NMUR2
SCHEMBL22694903 0.90 AHR (0.35) ALOX5NMUR2GABRPGABRDGABRA1
SCHEMBL18566649 0.90 AHR (0.32) ALOX5NMUR2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 49 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3309235-B1 ORGANIC LIGHT EMITTING ELEMENT HAVING HIGH EFFICIENCY SFC CO LTD (KR) 2023-10-18 EP disclosed
EP-3255692-B1 ORGANIC ELECTROLUMINESCENT ELEMENT HODOGAYA CHEMICAL CO LTD (JP) 2023-07-05 EP disclosed
US-11683980-B2 Condensed fluorene derivative comprising heterocyclic ring SFC CO., LTD. (KR) 2023-06-20 US disclosed
US-11683980-B2 Condensed fluorene derivative comprising heterocyclic ring SFC CO., LTD. (KR) 2023-06-20 US disclosed
US-11672172-B2 Heterocyclic compound comprising aromatic amine group and organic light-emitting diode including the same SFC CO., LTD. (KR) 2023-06-06 US disclosed
US-11672172-B2 Heterocyclic compound comprising aromatic amine group and organic light-emitting diode including the same SFC CO., LTD. (KR) 2023-06-06 US disclosed
EP-4116297-A1 CONDENSED FLUORENE DERIVATIVE COMPRISING HETEROCYCLIC RING SFC Co., Ltd. (KR) 2023-01-11 EP disclosed
EP-3223330-B1 ORGANIC ELECTROLUMINESCENT DEVICE HODOGAYA CHEMICAL CO LTD (JP) 2022-02-23 EP disclosed
US-11158811-B2 Organic electroluminescent device HODOGAYA CHEMICAL CO., LTD. (JP) 2021-10-26 US disclosed
EP-3240057-B1 ORGANIC ELECTROLUMINESCENT ELEMENT HODOGAYA CHEMICAL CO LTD (JP) 2021-04-07 EP disclosed
US-20170133600-A1 ORGANIC LIGHT-EMITTING DIODE WITH HIGH EFFICIENCY AND LOW VOLTAGE SFC CO., LTD. (KR) 2017-05-11 US disclosed
US-20170133600-A1 ORGANIC LIGHT-EMITTING DIODE WITH HIGH EFFICIENCY AND LOW VOLTAGE SFC CO., LTD. (KR) 2017-05-11 US disclosed
US-20170062729-A1 HETEROCYCLIC COMPOUND COMPRISING AROMATIC AMINE GROUP AND ORGANIC LIGHT-EMITTING DIODE INCLUDING THE SAME SFC CO., LTD. (KR) 2017-03-02 US disclosed
US-20170062729-A1 HETEROCYCLIC COMPOUND COMPRISING AROMATIC AMINE GROUP AND ORGANIC LIGHT-EMITTING DIODE INCLUDING THE SAME SFC CO., LTD. (KR) 2017-03-02 US disclosed
US-20170018723-A1 ORGANIC LIGHT EMITTING DIODE FOR HIGH EFFICIENCY SFC CO., LTD. (KR) 2017-01-19 US disclosed
US-20170018723-A1 ORGANIC LIGHT EMITTING DIODE FOR HIGH EFFICIENCY SFC CO., LTD. (KR) 2017-01-19 US disclosed
US-20170012214-A1 ORGANIC LIGHT-EMITTING DIODE WITH HIGH EFFICIENCY AND LONG LIFETIME SFC CO., LTD. (KR) 2017-01-12 US disclosed
US-20170012214-A1 ORGANIC LIGHT-EMITTING DIODE WITH HIGH EFFICIENCY AND LONG LIFETIME SFC CO., LTD. (KR) 2017-01-12 US disclosed
US-20160308137-A1 ORGANIC LIGHT EMITTING DIODE SFC CO., LTD. (KR) 2016-10-20 US disclosed
US-20160308137-A1 ORGANIC LIGHT EMITTING DIODE SFC CO., LTD. (KR) 2016-10-20 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20170018723-A1 ORGANIC LIGHT EMITTING DIODE FOR HIGH EFFICIENCY ALDH1A2, ALDH1A1, CYBA PDK2 445/4885ALOX5 456/4885NMUR2 2398/4885
US-11683980-B2 Condensed fluorene derivative comprising heterocyclic ring CCNE2, INF2, AFF4 PDK2 2097/4885ALOX5 862/4885NMUR2 2456/4885
US-20170012214-A1 ORGANIC LIGHT-EMITTING DIODE WITH HIGH EFFICIENCY AND LONG LIFETIME CRY2, CYBA, CRY1 PDK2 1453/4885ALOX5 732/4885NMUR2 2303/4885
US-20170062729-A1 HETEROCYCLIC COMPOUND COMPRISING AROMATIC AMINE GROUP AND ORGANIC LIGHT-EMITTING DIODE INCLUDING THE SAME DDC, TYR, AOC2 PDK2 2099/4885ALOX5 763/4885NMUR2 1093/4885
US-20170133600-A1 ORGANIC LIGHT-EMITTING DIODE WITH HIGH EFFICIENCY AND LOW VOLTAGE CYBA, ALDH1A2, AOC2 PDK2 864/4885ALOX5 660/4885NMUR2 1878/4885
US-11672172-B2 Heterocyclic compound comprising aromatic amine group and organic light-emitting diode including the same DDC, TYR, AOC2 PDK2 2099/4885ALOX5 763/4885NMUR2 1093/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.