Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ICMT | O60725 | 10/20 | 0.60 |
| ▸ | CACNB4 | O00305 | 2/20 | 0.58 |
| ▸ | CACNA1A | O00555 | 2/20 | 0.58 |
| ▸ | CACNA1G | O43497 | 2/20 | 0.58 |
| ▸ | CACNG3 | O60359 | 2/20 | 0.58 |
| ▸ | CACNA1F | O60840 | 2/20 | 0.58 |
| ▸ | CACNA1H | O95180 | 2/20 | 0.58 |
| ▸ | CACNB3 | P54284 | 2/20 | 0.58 |
| ▸ | CACNA2D1 | P54289 | 2/20 | 0.58 |
| ▸ | CACNG7 | P62955 | 2/20 | 0.58 |
| ▸ | CACNA1B | Q00975 | 2/20 | 0.58 |
| ▸ | CACNA1D | Q01668 | 2/20 | 0.58 |
| ▸ | CACNB1 | Q02641 | 2/20 | 0.58 |
| ▸ | CACNG1 | Q06432 | 2/20 | 0.58 |
| ▸ | CACNB2 | Q08289 | 2/20 | 0.58 |
| ▸ | CACNA1S | Q13698 | 2/20 | 0.58 |
| ▸ | CACNA1C | Q13936 | 2/20 | 0.58 |
| ▸ | CACNA1E | Q15878 | 2/20 | 0.58 |
| ▸ | CACNA2D4 | Q7Z3S7 | 2/20 | 0.58 |
| ▸ | CACNA2D3 | Q8IZS8 | 2/20 | 0.58 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1751127 | 0.87 | PLA2G2A (0.55) | ICMTPLA2G2AFNTAFNTBALDH1A1 | |
| SCHEMBL1750410 | 0.87 | PLA2G2A (0.55) | ICMTPLA2G2AFNTAFNTBALDH1A1 | |
| SCHEMBL7053553 | 0.78 | CACNB4 (0.62) | ICMTCACNB4CACNA1ACACNA1GCACNG3 | |
| SCHEMBL2004159 | 0.74 | PLA2G2A (0.81) | ICMTPLA2G2AALDH1A1LMNAPLA2G4A | |
| SCHEMBL20769700 | 0.74 | LMNA (0.75) | ICMTPLA2G2AALDH1A1LMNAPLA2G4A | |
| SCHEMBL13930959 | 0.73 | LMNA (0.74) | ICMTPLA2G2AALDH1A1LMNA | |
| SCHEMBL7962690 | 0.73 | PLA2G2A (0.74) | ICMTPLA2G2AALDH1A1LMNA | |
| SCHEMBL7679351 | 0.73 | ALDH1A1 (0.62) | ICMTPLA2G2AALDH1A1LMNAPLA2G4A | |
| SCHEMBL7683025 | 0.73 | ICMT (0.68) | ICMTPLA2G2AALDH1A1LMNAPLA2G4A | |
| SCHEMBL1073379 | 0.72 | TP53 (0.76) | ALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2666772-B1 | Synthesis of amines and intermediates for the synthesis thereof | BASF SE (DE) | 2017-03-01 | — | — | EP | disclosed |