Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDR | P35968 | 1/20 | 0.35 |
| ▸ | GABRA1 | P14867 | 3/20 | 0.35 |
| ▸ | GABRB2 | P47870 | 3/20 | 0.35 |
| ▸ | CCNE1 | P24864 | 3/20 | 0.32 |
| ▸ | CDK2 | P24941 | 3/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | LTA4H | P09960 | 1/20 | 0.32 |
| ▸ | DRD2 | P14416 | 1/20 | 0.31 |
| ▸ | DRD4 | P21917 | 1/20 | 0.31 |
| ▸ | DRD3 | P35462 | 1/20 | 0.31 |
| ▸ | SLC6A7 | Q99884 | 1/20 | 0.30 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20976710 | 1.00 | KDR (0.35) | KDRGABRA1GABRB2CCNE1CDK2 | |
| SCHEMBL20976745 | 1.00 | KDR (0.35) | KDRGABRA1GABRB2CCNE1CDK2 | |
| SCHEMBL18608669 | 0.82 | TSHR (0.36) | CCNE1CDK2ALDH1A1MEN1TSHR | |
| SCHEMBL18608670 | 0.81 | GABRA1 (0.42) | GABRA1GABRB2CCNE1CDK2ALDH1A1 | |
| SCHEMBL17019402 | 0.78 | PABPC1 (0.37) | GABRA1LTA4HDRD2DRD4DRD3 | |
| SCHEMBL5749127 | 0.61 | CNR1 (0.40) | GABRA1GABRB2 | |
| SCHEMBL15549773 | 0.61 | ALDH1A1 (0.46) | ALDH1A1LTA4HDRD2DRD3MEN1 | |
| SCHEMBL14873437 | 0.59 | ALDH1A1 (0.43) | ALDH1A1LTA4HDRD2DRD3MEN1 | |
| SCHEMBL24768084 | 0.59 | L3MBTL1 (0.51) | ALDH1A1TSHR | |
| SCHEMBL9357255 | 0.57 | TAAR1 (0.56) | ALDH1A1LTA4HDRD2DRD3MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170065586-A1 | SGC STIMULATORS | IRONWOOD PHARMACEUTICALS, INC. (US) | 2017-03-09 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170065586-A1 | SGC STIMULATORS | GUCY1B1, GUCY1A1, PRKG1 | KDR 438/4885GABRA1 2011/4885GABRB2 1126/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.