Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CES2 | O00748 | 3/20 | 0.48 |
| ▸ | CES1 | P23141 | 3/20 | 0.48 |
| ▸ | CA1 | P00915 | 3/20 | 0.38 |
| ▸ | CA2 | P00918 | 3/20 | 0.38 |
| ▸ | CA4 | P22748 | 2/20 | 0.38 |
| ▸ | CA12 | O43570 | 1/20 | 0.38 |
| ▸ | CA7 | P43166 | 1/20 | 0.38 |
| ▸ | CA13 | Q8N1Q1 | 1/20 | 0.38 |
| ▸ | KAT2B | Q92831 | 1/20 | 0.33 |
| ▸ | RAPGEF4 | Q8WZA2 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL788954 | 0.80 | CES2 (0.33) | CES2CES1CA1CA2CA4 | |
| SCHEMBL15671520 | 0.73 | HDAC1 (0.44) | — | |
| SCHEMBL28156146 | 0.72 | ANPEP (0.40) | CES2CES1 | |
| SCHEMBL78210 | 0.71 | CA1 (0.43) | CES2CES1CA1CA2CA4 | |
| SCHEMBL531337 | 0.69 | CES2 (0.52) | CES2CES1CA1CA2CA4 | |
| SCHEMBL1525706 | 0.69 | CES2 (0.45) | CES2CES1CA1CA2CA4 | |
| SCHEMBL12825674 | 0.69 | CES2 (0.39) | CES2CES1CA1CA2CA4 | |
| SCHEMBL78177 | 0.67 | CES2 (0.38) | CES2CES1CA1CA2CA4 | |
| SCHEMBL91852 | 0.67 | CES2 (0.43) | CES2CES1CA1CA2CA4 | |
| SCHEMBL12817090 | 0.67 | CA1 (0.40) | CES2CES1CA1CA2CA4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 190 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230142714-A1 | KETONE INHIBITORS OF LYSINE GINGIPAIN | Cortexyme, Inc. (US) | 2023-05-11 | — | — | US | claimed |
| US-10730826-B2 | Ketone inhibitors of lysine gingipain | Cortexyme, Inc. (US) | 2020-08-04 | — | — | US | claimed |
| EP-3512846-A1 | KETONE INHIBITORS OF LYSINE GINGIPAIN | Cortexyme, Inc. (US) | 2019-07-24 | — | — | EP | claimed |
| US-20190210960-A1 | KETONE INHIBITORS OF LYSINE GINGIPAIN | Cortexyme, Inc. (US) | 2019-07-11 | — | — | US | claimed |
| WO-2018053353-A1 | KETONE INHIBITORS OF LYSINE GINGIPAIN | Cortexyme, Inc. (US) | 2018-03-22 | — | — | WO | claimed |
| US-12029120-B2 | Organic electroluminescence element and electronic device | IDEMITSU KOSAN CO., LTD. (JP) | 2024-07-02 | — | — | US | disclosed |
| US-20240155942-A1 | ORGANIC ELECTROLUMINESCENCE ELEMENT AND ELECTRONIC DEVICE | IDEMITSU KOSAN CO.,LTD. (JP) | 2024-05-09 | — | — | US | disclosed |
| US-11944009-B2 | Compound, material for organic electroluminescent element, organic electroluminescent element, and electronic device | IDEMITSU KOSAN CO., LTD. (JP) | 2024-03-26 | — | — | US | disclosed |
| EP-3974433-B1 | ORGANIC ELECTROLUMINESCENT ELEMENT, COMPOUND, AND ELECTRONIC APPLIANCE | IDEMITSU KOSAN CO (JP) | 2024-02-21 | — | — | EP | disclosed |
| US-20230395857-A1 | NON-AQUEOUS ELECTROLYTE SOLUTION AND NON-AQUEOUS ELECTROLYTE SECONDARY BATTERY EMPLOYING THE SAME | MITSUBISHI CHEMICAL CORPORATION (JP) | 2023-12-07 | — | — | US | disclosed |
| US-11791499-B2 | Non-aqueous electrolyte solution and non-aqueous electrolyte secondary battery employing the same | MITSUBISHI CHEMICAL CORPORATION (JP) | 2023-10-17 | — | — | US | disclosed |
| CN-111372918-B | Compound, material for organic electroluminescent element, and electronic device | 出光兴产株式会社 | 2023-09-05 | — | — | CN | disclosed |
| US-20030060579-A1 | Catalyst component for addition polymerization, process for producing catalyst for addition polymerization and process for producing addition polymer | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2003-03-27 | — | — | US | disclosed |
| US-20020143124-A1 | Homogeneous type solid catalyst component or homogeneous type solid catalyst, process for production thereof and process for producing addition polymer with the same | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2002-10-03 | — | — | US | disclosed |
| US-20020058767-A1 | Method for producing an olefin type copolymer having a cyclic structure | MARUZEN PETROCHEMICAL CO., LTD. (JP) | 2002-05-16 | — | — | US | disclosed |
| EP-1205497-A2 | Method for producing an olefin type copolymer having a cyclic structure | MARUZEN PETROCHEMICAL CO., LTD. (JP) | 2002-05-15 | — | — | EP | disclosed |
| US-20010020075-A1 | Catalyst component for addition polymerization, catalyst for addition polymerization, and process for producing addition polymer | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2001-09-06 | — | — | US | disclosed |
| EP-1113026-A2 | Catalyst component for addition polymerization, catalyst for addition polymerization, and process for producing addition polymer | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2001-07-04 | — | — | EP | disclosed |
| US-5629406-A | AMINO ACID DERIVATIVES | SANKYO COMPANY, LIMITED (JP) | 1997-05-13 | — | — | US | disclosed |
| EP-0587311-A1 | Peptides capable of inhibiting the activity of HIV protease, their preparation and their therapeutic use | SANKYO COMPANY LIMITED (JP) | 1994-03-16 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11944009-B2 | Compound, material for organic electroluminescent element, organic electroluminescent element, and electronic device | LEF1, RER1, OR10J3 | CES2 1721/4885CES1 2710/4885CA1 2139/4885 |
| US-12029120-B2 | Organic electroluminescence element and electronic device | RPS10, H1-10, OR10J3 | CES2 1123/4885CES1 2923/4885CA1 834/4885 |
| US-20230142714-A1 | KETONE INHIBITORS OF LYSINE GINGIPAIN | PHYKPL, ENPEP, PREP | CES2 1035/4885CES1 124/4885CA1 262/4885 |
| US-20240155942-A1 | ORGANIC ELECTROLUMINESCENCE ELEMENT AND ELECTRONIC DEVICE | RPS10, H1-10, OR10J3 | CES2 1123/4885CES1 2923/4885CA1 834/4885 |
| US-10730826-B2 | Ketone inhibitors of lysine gingipain | PHYKPL, ENPEP, PREP | CES2 1035/4885CES1 124/4885CA1 262/4885 |
| US-20190210960-A1 | KETONE INHIBITORS OF LYSINE GINGIPAIN | PHYKPL, ENPEP, PREP | CES2 1035/4885CES1 124/4885CA1 262/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.