Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.53 |
| ▸ | CASP1 | P29466 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | ACHE | P22303 | 1/20 | 0.45 |
| ▸ | LTA4H | P09960 | 1/20 | 0.42 |
| ▸ | PREP | P48147 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28516086 | 0.98 | L3MBTL1 (0.55) | L3MBTL1CASP1ALDH1A1ACHELTA4H | |
| SCHEMBL6947156 | 0.95 | CASP1 (0.53) | L3MBTL1CASP1ALDH1A1PREPTSHR | |
| SCHEMBL1934716 | 0.88 | ALDH1A1 (0.50) | L3MBTL1CASP1ALDH1A1TSHR | |
| Trifluoroacetic Acid SCHEMBL6601200 | 0.85 | CASP1 (0.57) | L3MBTL1CASP1ALDH1A1PREPSMN1; SMN2 | |
| SCHEMBL31394302 | 0.80 | LTA4H (0.42) | L3MBTL1ALDH1A1LTA4HHRH3 | |
| SCHEMBL1749856 | 0.79 | LTA4H (0.41) | L3MBTL1ALDH1A1LTA4HHRH3 | |
| Hydrochloric Acid SCHEMBL1749447 | 0.79 | LTA4H (0.41) | ALDH1A1LTA4HHRH3 | |
| SCHEMBL6628631 | 0.78 | CASP1 (0.41) | L3MBTL1CASP1 | |
| SCHEMBL13386604 | 0.78 | ALDH1A1 (0.55) | ALDH1A1TSHR | |
| SCHEMBL18655950 | 0.78 | ALDH1A1 (0.47) | ALDH1A1LTA4HPREPHRH3TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9617256-B2 | Antibacterial agents | ACHAOGEN, INC. (US) | 2017-04-11 | — | — | US | disclosed |
| EP-1666551-B1 | Ink for ink jet-recording curable through irradiation and method for preparing lithographic printing plates using the same | FUJIFILM CORP (JP) | 2010-02-17 | — | — | EP | disclosed |
| US-7635181-B2 | Ink for ink jet-recording curable through irradiation with a radioactive ray and method for preparing lithographic printing plates using the same | FUJIFILM CORPORATION (JP) | 2009-12-22 | — | — | US | disclosed |
| US-7635181-B2 | Ink for ink jet-recording curable through irradiation with a radioactive ray and method for preparing lithographic printing plates using the same | FUJIFILM CORPORATION (JP) | 2009-12-22 | — | — | US | disclosed |
| EP-0161939-B1 | ARYLHYDROXAMATES | E.R. Squibb & Sons, Inc. (US) | 1993-07-21 | — | — | EP | disclosed |
| CN-85104470-A | The method for preparing arythydroxamtes | — | 1986-10-01 | — | — | CN | disclosed |
| US-4607053-A | L2POXYGENASE INHIBITORS | E. R. SQUIBB & SONS, INC. (US) | 1986-08-19 | — | — | US | disclosed |
| EP-0161939-A2 | Arylhydroxamates | E.R. Squibb & Sons, Inc. (US) | 1985-11-21 | — | — | EP | disclosed |