SCHEMBL6947156

SCHEMBL6947156

O=C1CCCN1OCc1ccccc1

nearest known ligand 0.53

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
CASP1 P29466 1/20 0.53
ALDH1A1 P00352 2/20 0.47
L3MBTL1 Q9Y468 1/20 0.46
TSHR P16473 2/20 0.42
PREP P48147 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9506098 0.95 L3MBTL1 (0.53) CASP1ALDH1A1L3MBTL1TSHRPREP
SCHEMBL28516086 0.93 L3MBTL1 (0.55) CASP1ALDH1A1L3MBTL1PREP
Trifluoroacetic Acid SCHEMBL6601200 0.90 CASP1 (0.57) CASP1ALDH1A1L3MBTL1PREP
SCHEMBL1934716 0.89 ALDH1A1 (0.50) CASP1ALDH1A1L3MBTL1TSHR
SCHEMBL6628631 0.83 CASP1 (0.41) CASP1L3MBTL1
Hydrochloric Acid SCHEMBL6602304 0.81 CASP1 (0.39) CASP1ALDH1A1
SCHEMBL13386604 0.80 ALDH1A1 (0.55) ALDH1A1TSHR
SCHEMBL15592597 0.79 ALDH1A1 (0.40) ALDH1A1TSHR
SCHEMBL5871698 0.79 ALDH1A1 (0.41) CASP1ALDH1A1
SCHEMBL21281736 0.79 CASP1 (0.53) CASP1ALDH1A1L3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117865867-A Synthesis method of 3-methyl-3-carbamic acid tert-butyl ester pyrrolidine-5-ketone 南通敏言生物医药科技有限公司 2024-04-12 CN claimed
CN-117865867-A Synthesis method of 3-methyl-3-carbamic acid tert-butyl ester pyrrolidine-5-ketone 南通敏言生物医药科技有限公司 2024-04-12 CN disclosed
WO-2003105827-A1 NEUROPROTECTION AND CARDIOPROTECTION AFFORDED BY CHELATORS WITH HIGH AFFINITY AND SPECIFICITY FOR CATIONS OF FIRST TRANSITION SERIES ELEMENTS CONCAT, LTD. (US) 2003-12-24 WO disclosed
EP-0944587-B1 METALLOPROTEINASE INHIBITORS BRITISH BIOTECH PHARM (GB) 2002-03-20 EP disclosed
EP-0944587-A1 METALLOPROTEINASE INHIBITORS BRITISH BIOTECH PHARMACEUTICALS LIMITED (GB) 1999-09-29 EP disclosed
US-5840974-A Metalloproteinase inhibitors BRITISCH BIOTECH PHARMACEUTICALS, LTD. (GB) 1998-11-24 US disclosed
WO-1998024759-A1 METALLOPROTEINASE INHIBITORS BRITISH BIOTECH PHARMACEUTICALS LIMITED (GB) 1998-06-11 WO disclosed