Known targets — ChEMBL curated mechanism
ABCC8ACEADORA1ADORA2AADORA2BADORA3ALDH5A1ALOX5ALOX5APATP4AATP4BBRAFCA1CA12CA2CA4CYSLTR1DHFRDPEP1EDNRAEDNRBESR2F10FDPSFGF1GABBR1GABBR2GABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGARTGNRHRGSC1HMGCRIMPDH1IMPDH2KCNJ11LY96NOD2NR3C1NS3NS4ANS5bP2RY1P2RY12P2RY2P2RY4P2RY6PBP2XPDE3APDE3BPDE4APDE4BPDE4CPDE4DPDK1PDK2PDK3PDK4PPARGPPATPTGIRPTGS1PTGS2RAF1RYR1RYR3SCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASERPINC1SLC12A1SLC12A3SYKTHRATHRBTLR3TLR4TLR9TUBA1ATUBA1BTUBA1CTUBA3CTUBA3ETUBA4ATUBBTUBB1TUBB2ATUBB2BTUBB3TUBB4ATUBB4BTUBB6TUBB8TYMSVKORC1XDHblablaIMP-1blaOXA-33blaOXA-58blaT-3blaT-4blaT-5blaT-6dacAdacBdacCfolAfolPfolP1ftsIfusAgaggyrAgyrBmecAmrcAmrcBmrdApbp1apbp1bpbp2pbp2apbp2bpbp3pbp4pbpApbpBpbpCpbpFpolponBrplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpoArpoBrpoCrpoZrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of None. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 known ✓ | P00915 | 3/20 | 0.46 |
| ▸ | CA2 known ✓ | P00918 | 3/20 | 0.46 |
| ▸ | CA12 known ✓ | O43570 | 2/20 | 0.46 |
| ▸ | XDH known ✓ | P47989 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 11/20 | 0.55 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.54 |
| ▸ | HPGD | P15428 | 5/20 | 0.54 |
| ▸ | MAPT | P10636 | 3/20 | 0.54 |
| ▸ | CASP1 | P29466 | 2/20 | 0.54 |
| ▸ | CASP7 | P55210 | 2/20 | 0.54 |
| ▸ | GAA | P10253 | 2/20 | 0.54 |
| ▸ | ATM | Q13315 | 2/20 | 0.54 |
| ▸ | GLA | P06280 | 1/20 | 0.54 |
| ▸ | VCAM1 | P19320 | 1/20 | 0.48 |
| ▸ | CA9 | Q16790 | 3/20 | 0.46 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.46 |
| ▸ | CA7 | P43166 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Potassium Ion SCHEMBL1863797 | 0.97 | KDM4E (0.55) | KDM4EHSD17B10SMN1; SMN2ALDH1A1HPGD | |
| SCHEMBL4606537 | 0.97 | KDM4E (0.55) | KDM4EHSD17B10SMN1; SMN2ALDH1A1HPGD | |
| SCHEMBL4605912 | 0.97 | KDM4E (0.55) | KDM4EHSD17B10SMN1; SMN2ALDH1A1HPGD | |
| SCHEMBL4604662 | 0.97 | KDM4E (0.55) | KDM4EHSD17B10SMN1; SMN2ALDH1A1HPGD | |
| SCHEMBL3341066 | 0.87 | KDM4E (0.51) | KDM4EHSD17B10SMN1; SMN2ALDH1A1HPGD | |
| SCHEMBL5994468 | 0.84 | KDM4E (0.46) | KDM4EHSD17B10SMN1; SMN2ALDH1A1HPGD | |
| SCHEMBL3339517 | 0.83 | KDM4E (0.58) | KDM4EHSD17B10SMN1; SMN2ALDH1A1HPGD | |
| SCHEMBL4602708 | 0.82 | KDM4E (0.56) | KDM4EHSD17B10SMN1; SMN2ALDH1A1HPGD | |
| SCHEMBL1863796 | 0.82 | KDM4E (0.56) | KDM4EHSD17B10SMN1; SMN2ALDH1A1HPGD | |
| Cesium SCHEMBL4605888 | 0.82 | KDM4E (0.56) | KDM4EHSD17B10SMN1; SMN2ALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2019166-B1 | OLIGOMER REMOVER FOR POLYESTER FIBER MATERIAL | NICCA CHEMICAL CO (JP) | 2016-03-02 | — | — | EP | disclosed |
| US-8324338-B2 | Oligomer removing agent for polyester-based fiber material | NICCA CHEMICAL CO., LTD. (JP) | 2012-12-04 | — | — | US | disclosed |
| US-20110107526-A1 | OLIGOMER REMOVING AGENT FOR POLYESTER-BASED FIBER MATERIAL | NICCA CHEMICAL CO., LTD. (JP) | 2011-05-12 | — | — | US | disclosed |
| EP-2218820-A1 | DYEABILITY IMPROVER FOR POLYESTER FIBER MATERIAL | NICCA CHEMICAL CO., LTD. (JP) | 2010-08-18 | — | — | EP | disclosed |
| US-20100152408-A1 | MANUFACTURING METHOD OF BIODEGRADABLE WATER-BASED POLYESTER RESIN | JAYEONSARANG CO., LTD. (KP) | 2010-06-17 | — | — | US | disclosed |
| US-20100064451-A1 | DYEING QUALITY IMPROVER FOR POLYESTER-BASED FIBER MATERIALS | NICCA CHEMICAL CO., LTD. (JP) | 2010-03-18 | — | — | US | disclosed |
| EP-2102266-A1 | MANUFACTURING METHOD OF BIODEGRADABLE WATER-BASED POLYESTER RESIN | Jayeonsarang CO. LTD (KR) | 2009-09-23 | — | — | EP | disclosed |
| US-20090036640-A1 | Oligomer Removing Agent for Polyester-Based Fiber Material | NICCA CHEMICAL CO., LTD. (JP) | 2009-02-05 | — | — | US | disclosed |
| EP-2019166-A1 | OLIGOMER REMOVER FOR POLYESTER FIBER MATERIAL | NICCA CHEMICAL CO., LTD. (JP) | 2009-01-28 | — | — | EP | disclosed |
| WO-2008075924-A1 | MANUFACTURING METHOD OF BIODEGRADABLE WATER-BASED POLYESTER RESIN | JAYEONSARANG CO. LTD (KR) | 2008-06-26 | — | — | WO | disclosed |